Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment

Biomaterials

Volumn 33, Issue 4, 2012, Pages 1180-1189

  Kumar, Anil ^a   Ma, Huili ^a   Zhang, Xu ^a   Huang, Keyang ^a   Jin, Shubin ^a   Liu, Juan ^a   Wei, Tuo ^a   Cao, Weipeng ^a   Zou, Guozhang ^a   Liang, Xing Jie ^a  

^a NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

Author keywords

Cancer treatment; Gold nanoparticles (AuNPs); Neuropilin 1 (Nrp 1) receptor; P53 mechanism; Targeted peptide (CRGDK); Therapeutic peptide PMI (p12)

Indexed keywords

BINDING INTERACTION; BIOLOGICAL MOLECULE; BIOMEDICAL IMAGING; CANCER CELLS; CELL SURFACES; CLINICAL DIAGNOSIS; FUNCTIONALIZATIONS; FUNCTIONALIZED; GOLD NANOPARTICLE; GOLD NANOPARTICLES; HYBRID MODEL; INTRACELLULAR UPTAKE; MEDICINAL APPLICATIONS; NEUROPILIN-1 (NRP-1) RECEPTOR; SELECTIVE BINDING; SURFACE CONJUGATION; TARGET BINDING; TARGETED PEPTIDE (CRGDK); THERAPEUTIC EFFECTS; THERAPEUTIC PEPTIDES;

BINDING ENERGY; CELL MEMBRANES; DIAGNOSIS; DISEASES; GOLD; MEDICAL IMAGING; NANOPARTICLES; ONCOLOGY;

PEPTIDES;

ANTINEOPLASTIC AGENT; GOLD NANOPARTICLE; MEMBRANE RECEPTOR; NEUROPILIN 1; P12 PEPTIDE CONJUGATED CYSTEINYLARGINYLGLYCYLASPARTYLLYSINE; PROTEIN P53; TIOPRONIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SYNTHESIS; DRUG TARGETING; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLUBILITY;

ADENOCARCINOMA; AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FEMALE; GOLD; HUMANS; NANOPARTICLES; NEUROPILIN-1; OLIGOPEPTIDES; PEPTIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 81355122667     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.10.058     Document Type: Article

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