Nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats

Synapse

Volumn 64, Issue 2, 2010, Pages 136-145

  Natividad, Luis A ^a   Tejeda, Hugo A ^a   Torres, Oscar V ^a   O'Dell, Laura E ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

Author keywords

5 HIAA; Abstinence; Adolescence; Bicuculline; Development; DOPAC; GABA; High performance liquid chromatography (HPLC) EC; HVA; In vivo microdialysis; Nicotinic; Ventral tegmental area

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 5 HYDROXYINDOLEACETIC ACID; BICUCULLINE; DOPAMINE; HOMOVANILLIC ACID; MECAMYLAMINE; NICOTINE;

ADOLESCENCE; ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIALYSATE LEVEL; DOPAMINE BRAIN LEVEL; DOPAMINERGIC TRANSMISSION; DRUG EXPOSURE; DRUG WITHDRAWAL; FOLLOW UP; GROUPS BY AGE; MALE; MICRODIALYSIS; MOLECULAR MECHANICS; NEUROCHEMISTRY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; VENTRAL TEGMENTUM;

3,4-DIHYDROXYPHENYLACETIC ACID; AGING; ANIMALS; BICUCULLINE; DOPAMINE; EXTRACELLULAR SPACE; GABA ANTAGONISTS; HYDROXYINDOLEACETIC ACID; MALE; MECAMYLAMINE; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; NUCLEUS ACCUMBENS; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SUBSTANCE WITHDRAWAL SYNDROME; VENTRAL TEGMENTAL AREA;

EID: 72449136736     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20713     Document Type: Article

References (50)

1. Azam L, Chen Y, Leslie FM. 2007. Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons. Neuroscience 144:1347-1360. (Pubitemid 46123818)
2. Buchhalter AR, Fant RV, Henningfield JE. 2008. Novel pharmacological approaches for treating tobacco dependence and withdrawal: Current status. Drugs 68:1067-1088.
3. Benowitz NL. 2008. Neurobiology of nicotine addiction: Implications for smoking cessation treatment. Am J Med 121:3-10.
4. Berrendero F, Kieffer BL, Maldonado R. 2002. Attenuation of nicotine- induced antinociception, rewarding effects, and dependence in mu-opioid receptor knock-out mice. J Neurosci 22:10935-10940. (Pubitemid 36005169)
5. Carboni E, Bortone L, Giua C, Di Chiara G. 2000. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug Alcohol Depend 58:93-102.
6. Carmody TP, Vieten C, Astin JA. 2007. Negative affect, emotional acceptance, and smoking cessation. J Psychoactive Drugs 39:499-508.
7. Chen H, Matta SG, Sharp BM. 2007. Acquisition of nicotine self-administration in adolescent rats given prolonged access to the drug. Neuropsychopharmacology 32:700-709. (Pubitemid 46271065)
8. Cherubini E, Gaiarsa JL, Ben-Ari Y. 1991. GABA: An excitatory transmitter in early postnatal life. Trends Neurosci 14:515-519.
9. Cohen AS, Lin DD, Coulter DA. 2000. Protracted postnatal development of inhibitory synaptic transmission in rat hippocampal area CA1 neurons. J Neurophysiol 84:2465-2476. (Pubitemid 30844440)
10. Corrigall WA. 1991. Understanding brain mechanisms in nicotine reinforcement. Br J Addict 86:507-510.
11. Gaddnas H, Piepponen TP, Ahtee L. 2002. Mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine. Neurosci Lett 330:219-222. (Pubitemid 35254039)
12. Hanson K, Allen S, Jensen S, Hatsukami D. 2003. Treatment of adolescent smokers with the nicotine patch. Nicotine Tobacco Res 5:515-526. (Pubitemid 37081132)
13. Hildebrand BE, Nomikos GG, Hertel P, Schilstrom B, Svensson TH. 1998. Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine- precipitated nicotine withdrawal syndrome. Brain Res 779:214-225. (Pubitemid 28039954)
14. Hildebrand BE, Panagis G, Svensson TH, Nomikos GG. 1999. Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: Role of nicotinic receptors in the ventral tegmental area. Neuropsychopharmacology 21:560-574. (Pubitemid 29414801)
15. Hildebrand BE, Svensson TH. 2000. Intraaccumbal mecamylamine infusion does not affect dopamine output in the nucleus accumbens of chronically nicotine-treated rats. J Neural Trans 107:861-872.
16. Hurt RD, Croghan GA, Beede SD, Wolter TD, Croghan IT, Patten CA. 2000. Nicotine patch therapy in 101 adolescent smokers: Efficacy, withdrawal symptom relief, and carbon monoxide and plasma cotinine levels. Arch Pediatrics Adolescent Med 154:31-37.
17. Ikemoto S, Kohl RR, McBride WJ. 1997. GABA-A receptor blockade in the anterior ventral tegmental area increases extracellular levels of dopamine in the nucleus accumbens of rats. J Neurochem 69:137-143. (Pubitemid 27274166)
18. Johnson SW, North RA. 1992. Two types of neurons in the rat ventral tegmental area and their synaptic inputs. J Physiol (Lond) 450:455-468.
19. Kalivas PW. 1993. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res Rev 18:75-113. (Pubitemid 23090012)
20. Killen JD, Ammerman S, Rojas N, Varady J, Haydel F, Robinson TN. 2001. Do adolescent smokers experience withdrawal effects when deprived of nicotine? Exp Clin Psychopharmacol 9:176-182.
21. Kota D, Martin BR, Robinson SE, Damaj MI. 2007. Nicotine dependence and reward differ between adolescent and adult male mice. J Pharmacol Exp Therapeutics 322:399-407. (Pubitemid 46956383)
22. Kota D, Martin BR, Damaj MI. 2008. Age-dependent differences in nicotine reward and withdrawal in female mice. Psychopharmacology 198:201-210.
23. Levin ED, Rezvani A, Montoya R, Rose J, Swartrzwelder H. 2003. Adolescent-onset nicotine self-administration modeled in female rats. Psychopharmacology 169:141-149. (Pubitemid 37129965)
24. Levin ED, Lawrence SS, Petro A, Horton K, Rezvani AH, Seidler FJ, Slotkin TA. 2007. Adolescent vs. adult-onset nicotine selfadministration in male rats: Duration of effect and differential nicotinic receptor correlates. Neurotoxicol Teratol 29:458-465. (Pubitemid 46818888)
25. Malin DH, Lake JR, Carter VA, Cunningham JS, Hebert KM, Conrad DL, Wilson OB. 1994. The nicotinic antagonist mecamylamine precipitates nicotine abstinence syndrome in the rat. Psychopharmacology (Berlin) 115:180-184.
26. Mansvelder HD, McGehee DS. 2002. Cellular and synaptic mechanisms of nicotine addiction. J Neurobiol 53:606-617.
27. Mansvelder HD, Keath JR, McGehee DS. 2002. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron 33:905-919.
28. Moolchan ET, Robinson ML, Ernst M, Cadet JL, Pickworth WB, Heishman SJ, Schroeder JR. 2005. Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addiction. Pediatrics 115:407-414.
29. O'Dell LE, Parsons LH. 2004. Serotonin-1B receptors in the ventral tegmental area modulate cocaine-induced increases in nucleus accumbens dopamine levels. J Pharmacol Exp Therapeutics 311:711-719.
30. O'Dell LE, Bruijnzeel AW, Ghozland S, Markou A, Koob GF. 2004. Nicotine withdrawal in adolescent and adult rats. Ann NY Acad Sci 1021:167-174. (Pubitemid 38879623)
31. O'Dell LE, Bruijnzeel AW, Smith RT, Parsons LH, Merves ML, Goldberger BA, Koob GF, Markou A. 2006. Diminished nicotine withdrawal in adolescent rats: Implications for vulnerability to addiction. Psychopharmacology 186:612-619. (Pubitemid 43855849)
32. O'Dell LE, Torres OV, Natividad LA, Tejeda HA. 2007. Adolescent nicotine exposure produces less affective measures of withdrawal relative to adult nicotine exposure in male rats. Neurotoxicol Teratol 29:17-22.
33. Paxinos G, Watson C. 1998. The rat brain in stereotaxic coordinates, 4th ed. New York: Academic Press.
34. Philpot RM, McQuown S, Kirstein CL. 2001. Stereotaxic localization of the developing nucleus accumbens septi. Develop Brain Res 130:149-153. (Pubitemid 32830984)
35. Pistis M, Perra S, Pillolla G, Melis M, Muntoni AL, Gessa GL. 2004. Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons. Biol Psychiatry 56:86-94. (Pubitemid 38849412)
36. Pothos E, Rada P, Mark GP, Hoebel BG. 1991. Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment. Brain Res 566:348-350
37. Rada P, Jensen K, Hoebel BG. 2001. Effects of nicotine and mecamylamine- induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens. Psychopharmacology 157:105-110. (Pubitemid 32758966)
38. Rada P, Johnson DF, Lewis MJ, Hoebel BG. 2004. In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: Evidence of opioid withdrawal. Pharmacol Biochem Behav 79:599-605.
39. Salas R, Pieri F, De Biasi M. 2004. Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit. J Neurosci 24:10035-10039. (Pubitemid 39492026)
40. Shearman E, Fallon S, Sershen H, Lajtha A. 2008. Nicotine-induced monoamine neurotransmitter changes in the brain of young rats. Brain Res Bull 76:626-639.
41. Shram MJ, Funk D, Li Z, Le AD. 2006. Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine. Psychopharmacology 186:201-208.
42. Shram MJ, Siu EC, Li Z, Tyndale RF, Le AD. 2008. Interactions between age and the aversive effects of nicotine withdrawal under mecamylamine-precipitated and spontaneous conditions in male Wistar rats. Psychopharmacology 198:181-190.
43. Smith AE, Cavallo DA, Dahl T, Wu R, George TP, Krishnan-Sarin S. 2008a. Effects of acute tobacco abstinence in adolescent smokers as compared with nonsmokers. J Adolescent Health 43:46-54.
44. Smith AE, Cavallo DA, McFetridge A, Liss T, Krishnan-Sarin S. 2008b. Preliminary examination of tobacco withdrawal in adolescent smokers during smoking cessation treatment. Nicotine Tobacco Res 10:1253-1259. (Pubitemid 352044712)
45. Torres OV, Tejeda HA, Natividad LA, O'Dell LE. 2008. Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development. Pharmacol Biochem Behav 90:658-663.
46. Trauth JA, Seidler FJ, Slotkin TA. 2000. An animal model of adolescent nicotine exposure: Effects on gene expression and macromolecular constituents in rat brain regions. Brain Res 867:29-39.
47. Vastola BJ, Douglas LA, Varlinskaya EI, Spear LP. 2002. Nicotine-induced conditioned place preference in adolescent and adult rats. Physiol Behav 77:107-114. (Pubitemid 35245726)
48. Watkins SS, Koob GF, Markou A. 2000. Neural mechanisms underlying nicotine addiction: Acute positive reinforcement and withdrawal. Nicotine Tobacco Res 2:19-37.
49. Weiss F, Markou A, Lorang MT, Koob GF. 1992. Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Res 593:314-318.
50. Westerink BH, Kwint HF, deVries JB. 1996. The pharmacology of mesolimbic dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain. J Neurosci 16:2605-2611.