메뉴 건너뛰기




Volumn 40, Issue 19, 2012, Pages 9543-9556

Diverse control of metabolism and other cellular processes in Streptomyces coelicolor by the PhoP transcription factor: Genome-wide identification of in vivo targets

Author keywords

[No Author keywords available]

Indexed keywords

PHOP PROTEIN; PHOSPHATE; TRANSCRIPTOME;

EID: 84868160004     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks766     Document Type: Article
Times cited : (82)

References (52)
  • 3
    • 40249107679 scopus 로고    scopus 로고
    • Target genes and structure of the direct repeats in the DNA-binding sequences of the response regulator PhoP in Streptomyces coelicolor
    • DOI 10.1093/nar/gkm1150
    • Sola-Landa, A., Rodriguez-Garcia, A., Apel, A.K. and Martin, J.F. (2008) Target genes and structure of the direct repeats in the DNA-binding sequences of the response regulator PhoP in Streptomyces coelicolor. Nucleic Acids Res., 36, 1358-1368. (Pubitemid 351330950)
    • (2008) Nucleic Acids Research , vol.36 , Issue.4 , pp. 1358-1368
    • Sola-Landa, A.1    Rodriguez-Garcia, A.2    Apel, A.K.3    Martin, J.F.4
  • 4
    • 35448940010 scopus 로고    scopus 로고
    • Phosphate control of phoA, phoC and phoD gene expression in Streptomyces coelicolor reveals significant differences in binding of PhoP to their promoter regions
    • DOI 10.1099/mic.0.2007/007070-0
    • Apel, A.K., Sola-Landa, A., Rodriguez-Garcia, A. and Martin, J.F. (2007) Phosphate control of phoA, phoC and phoD gene expression in Streptomyces coelicolor reveals significant differences in binding of PhoP to their promoter regions. Microbiology, 153, 3527-3537. (Pubitemid 47629556)
    • (2007) Microbiology , vol.153 , Issue.10 , pp. 3527-3537
    • Apel, A.K.1    Sola-Landa, A.2    Rodriguez-Garcia, A.3    Martin, J.F.4
  • 5
    • 67650741686 scopus 로고    scopus 로고
    • Phosphate and carbon source regulation of two PhoP-dependent glycerophosphodiester phosphodiesterase genes of Streptomyces coelicolor
    • Santos-Beneit, F., Rodriguez-Garcia, A., Apel, A.K. and Martin, J.F. (2009) Phosphate and carbon source regulation of two PhoP-dependent glycerophosphodiester phosphodiesterase genes of Streptomyces coelicolor. Microbiology, 155, 1800-1811.
    • (2009) Microbiology , vol.155 , pp. 1800-1811
    • Santos-Beneit, F.1    Rodriguez-Garcia, A.2    Apel, A.K.3    Martin, J.F.4
  • 6
    • 0032879027 scopus 로고    scopus 로고
    • Forty years of genetics with Streptomyces: From in vivo through in vitro to in silico
    • Hopwood, D.A. (1999) Forty years of genetics with Streptomyces: from in vivo through in vitro to in silico. Microbiology, 145, 2183-2202. (Pubitemid 29454337)
    • (1999) Microbiology , vol.145 , Issue.9 , pp. 2183-2202
    • Hopwood, D.A.1
  • 8
    • 0036380072 scopus 로고    scopus 로고
    • Principles of microbial alchemy: Insights from the Streptomyces coelicolor genome sequence
    • Thompson, C.J., Fink, D. and Nguyen, L.D. (2002) Principles of microbial alchemy: insights from the Streptomyces coelicolor genome sequence. Genome Biol., 3, 1020.
    • (2002) Genome Biol. , vol.3 , pp. 1020
    • Thompson, C.J.1    Fink, D.2    Nguyen, L.D.3
  • 10
    • 33847661977 scopus 로고    scopus 로고
    • The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis
    • DOI 10.1016/j.ymben.2006.10.003, PII S1096717606001066
    • Mendes, M.V., Tunca, S., Anton, N., Recio, E., Sola-Landa, A., Aparicio, J.F. and Martin, J.F. (2007) The two-component phoR-phoP system of Streptomyces natalensis: inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis. Metab. Eng., 9, 217-227. (Pubitemid 46350704)
    • (2007) Metabolic Engineering , vol.9 , Issue.2 , pp. 217-227
    • Mendes, M.V.1    Tunca, S.2    Anton, N.3    Recio, E.4    Sola-Landa, A.5    Aparicio, J.F.6    Martin, J.F.7
  • 11
    • 3843050181 scopus 로고    scopus 로고
    • Phosphate control of the biosynthesis of antibiotics and other secondary metabolites is mediated by the PhoR-PhoP system: An unfinished story
    • DOI 10.1128/JB.186.16.5197-5201.2004
    • Martin, J.F. (2004) Phosphate control of the biosynthesis of antibiotics and other secondary metabolites is mediated by the PhoR-PhoP system: an unfinished story. J.Bacteriol., 186, 5197-5201. (Pubitemid 39038122)
    • (2004) Journal of Bacteriology , vol.186 , Issue.16 , pp. 5197-5201
    • Martin, J.F.1
  • 12
    • 62949243440 scopus 로고    scopus 로고
    • Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription
    • Santos-Beneit, F., Rodriguez-Garcia, A., Sola-Landa, A. and Martin, J.F. (2009) Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription. Mol. Microbiol., 72, 53-68.
    • (2009) Mol. Microbiol. , vol.72 , pp. 53-68
    • Santos-Beneit, F.1    Rodriguez-Garcia, A.2    Sola-Landa, A.3    Martin, J.F.4
  • 13
    • 67249083329 scopus 로고    scopus 로고
    • Phosphate control over nitrogen metabolism in Streptomyces coelicolor: Direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP
    • Rodrguez-Garca, A., Sola-Landa, A., Apel, K., Santos-Beneit, F. and Martn, J.F. (2009) Phosphate control over nitrogen metabolism in Streptomyces coelicolor: direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP. Nucleic Acids Res., 37, 3230-3242.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 3230-3242
    • Rodrguez-Garca, A.1    Sola-Landa, A.2    Apel, K.3    Santos-Beneit, F.4    Martn, J.F.5
  • 14
    • 0036231769 scopus 로고    scopus 로고
    • The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans
    • DOI 10.1046/j.1365-2958.2002.02557.x
    • Chouayekh, H. and Virolle, M.J. (2002) The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans. Mol. Microbiol., 43, 919-930. (Pubitemid 34415716)
    • (2002) Molecular Microbiology , vol.43 , Issue.4 , pp. 919-930
    • Chouayekh, H.1    Virolle, M.-J.2
  • 15
    • 34547144162 scopus 로고    scopus 로고
    • Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a phoP mutant
    • DOI 10.1002/pmic.200600883
    • Rodriguez-Garcia, A., Barreiro, C., Santos-Beneit, F., Sola-Landa, A. and Martin, J.F. (2007) Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a Delta phoP mutant. Proteomics, 7, 2410-2429. (Pubitemid 47121533)
    • (2007) Proteomics , vol.7 , Issue.14 , pp. 2410-2429
    • Rodriguez-Garcia, A.1    Barreiro, C.2    Santos-Beneit, F.3    Sola-Landa, A.4    Martin, J.F.5
  • 16
    • 79955531028 scopus 로고    scopus 로고
    • Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators
    • Santos-Beneit, F., Rodriguez-Garcia, A. and Martin, J.F. (2011) Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators. J. Bacteriol., 193, 2242-2251.
    • (2011) J. Bacteriol. , vol.193 , pp. 2242-2251
    • Santos-Beneit, F.1    Rodriguez-Garcia, A.2    Martin, J.F.3
  • 18
    • 23844490045 scopus 로고    scopus 로고
    • The high-affinity phosphate-binding protein PstS is accumulated under high fructose concentrations and mutation of the corresponding gene affects differentiation in Streptomyces lividans
    • DOI 10.1099/mic.0.27983-0
    • Diaz, M., Esteban, A., Fernandez-Abalos, J.M. and Santamaria, R.I. (2005) The high-affinity phosphate-binding protein PstS is accumulated under high fructose concentrations and mutation of the corresponding gene affects differentiation in Streptomyces lividans. Microbiology, 151, 2583-2592. (Pubitemid 41149781)
    • (2005) Microbiology , vol.151 , Issue.8 , pp. 2583-2592
    • Diaz, M.1    Esteban, A.2    Fernandez-Abalos, J.M.3    Santamaria, R.I.4
  • 19
    • 69449094147 scopus 로고    scopus 로고
    • Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: Characterization of the HspR regulon
    • Bucca, G., Laing, E., Mersinias, V., Allenby, N., Hurd, D., Holdstock, J., Brenner, V., Harrison, M. and Smith, C.P. (2009) Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon. Genome Biol., 10, R5.
    • (2009) Genome Biol. , vol.10
    • Bucca, G.1    Laing, E.2    Mersinias, V.3    Allenby, N.4    Hurd, D.5    Holdstock, J.6    Brenner, V.7    Harrison, M.8    Smith, C.P.9
  • 20
    • 0028282570 scopus 로고
    • Substrate induction and catabolite repression of the Streptomyces coelicolor glycerol operon are mediated through the GylR protein
    • Hindle, Z. and Smith, C.P. (1994) Substrate induction and catabolite repression of the Streptomyces coelicolor glycerol operon are mediated through the GylR protein. Mol. Microbiol., 12, 737-745.
    • (1994) Mol. Microbiol. , vol.12 , pp. 737-745
    • Hindle, Z.1    Smith, C.P.2
  • 23
    • 0242333835 scopus 로고    scopus 로고
    • Normalization of cDNA microarray data
    • DOI 10.1016/S1046-2023(03)00155-5
    • Smyth, G.K. and Speed, T. (2003) Normalization of cDNA microarray data. Methods, 31, 265-273. (Pubitemid 37338763)
    • (2003) Methods , vol.31 , Issue.4 , pp. 265-273
    • Smyth, G.K.1    Speed, T.2
  • 24
    • 4344571581 scopus 로고    scopus 로고
    • Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments
    • DOI 10.1016/j.febslet.2004.07.055, PII S0014579304009354
    • Breitling, R., Armengaud, P., Amtmann, A. and Herzyk, P. (2004) Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett., 573, 83-92. (Pubitemid 39141040)
    • (2004) FEBS Letters , vol.573 , Issue.1-3 , pp. 83-92
    • Breitling, R.1    Armengaud, P.2    Amtmann, A.3    Herzyk, P.4
  • 26
    • 33751006151 scopus 로고    scopus 로고
    • RankProd: A bioconductor package for detecting differentially expressed genes in meta-analysis
    • DOI 10.1093/bioinformatics/btl476
    • Hong, F., Breitling, R., McEntee, C.W., Wittner, B.S., Nemhauser, J.L. and Chory, J. (2006) RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics, 22, 2825-2827. (Pubitemid 44742407)
    • (2006) Bioinformatics , vol.22 , Issue.22 , pp. 2825-2827
    • Hong, F.1    Breitling, R.2    McEntee, C.W.3    Wittner, B.S.4    Nemhauser, J.L.5    Chory, J.6
  • 27
    • 52749097035 scopus 로고    scopus 로고
    • Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules
    • Turatsinze, J.V., Thomas-Chollier, M., Defrance, M. and van Helden, J. (2008) Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules. Nat. Protoc., 3, 1578-1588.
    • (2008) Nat. Protoc. , vol.3 , pp. 1578-1588
    • Turatsinze, J.V.1    Thomas-Chollier, M.2    Defrance, M.3    Van Helden, J.4
  • 28
    • 19944370498 scopus 로고    scopus 로고
    • Binding of PhoP to promoters of phosphate-regulated genes in Streptomyces coelicolor: Identification of PHO boxes
    • DOI 10.1111/j.1365-2958.2005.04631.x
    • Sola-Landa, A., Rodriguez-Garcia, A., Franco-Dominguez, E. and Martin, J.F. (2005) Binding of PhoP to promoters of phosphate-regulated genes in Streptomyces coelicolor: identification of PHO boxes. Mol. Microbiol., 56, 1373-1385. (Pubitemid 40756017)
    • (2005) Molecular Microbiology , vol.56 , Issue.5 , pp. 1373-1385
    • Sola-Landa, A.1    Rodriguez-Garcia, A.2    Franco-Dominguez, E.3    Martin, J.F.4
  • 29
    • 38449097896 scopus 로고    scopus 로고
    • The Streptomyces coelicolor GlnR regulon: Identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes
    • DOI 10.1111/j.1365-2958.2007.06092.x
    • Tiffert, Y., Supra, P., Wurm, R., Wohlleben, W., Wagner, R. and Reuther, J. (2008) The Streptomyces coelicolor GlnR regulon: identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes. Mol. Microbiol., 67, 861-880. (Pubitemid 351143689)
    • (2008) Molecular Microbiology , vol.67 , Issue.4 , pp. 861-880
    • Tiffert, Y.1    Supra, P.2    Wurm, R.3    Wohlleben, W.4    Wagner, R.5    Reuther, J.6
  • 32
    • 46449120734 scopus 로고    scopus 로고
    • Feast or famine: The global regulator DasR links nutrient stress to antibiotic production by Streptomyces
    • DOI 10.1038/embor.2008.83, PII EMBOR200883
    • Rigali, S., Titgemeyer, F., Barends, S., Mulder, S., Thomae, A.W., Hopwood, D.A. and van Wezel, G.P. (2008) Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces. EMBO Rep., 9, 670-675. (Pubitemid 351927688)
    • (2008) EMBO Reports , vol.9 , Issue.7 , pp. 670-675
    • Rigali, S.1    Titgemeyer, F.2    Barends, S.3    Mulder, S.4    Thomae, A.W.5    Hopwood, D.A.6    Van Wezel, G.P.7
  • 33
    • 55549086417 scopus 로고    scopus 로고
    • Streptomyces morphogenetics: Dissecting differentiation in a filamentous bacterium
    • Flardh, K. and Buttner, M.J. (2009) Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium. Nat. Rev. Microbiol., 7, 36-49.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 36-49
    • Flardh, K.1    Buttner, M.J.2
  • 34
    • 78649368524 scopus 로고    scopus 로고
    • Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth
    • den Hengst, C.D., Tran, N.T., Bibb, M.J., Chandra, G., Leskiw, B.K. and Buttner, M.J. (2010) Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth. Mol. Microbiol., 78, 361-379.
    • (2010) Mol. Microbiol. , vol.78 , pp. 361-379
    • Den Hengst, C.D.1    Tran, N.T.2    Bibb, M.J.3    Chandra, G.4    Leskiw, B.K.5    Buttner, M.J.6
  • 35
    • 84860390298 scopus 로고    scopus 로고
    • Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus
    • Higo, A., Horinouchi, S. and Ohnishi, Y. (2011) Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus. Mol. Microbiol., 81, 1607-1622.
    • (2011) Mol. Microbiol. , vol.81 , pp. 1607-1622
    • Higo, A.1    Horinouchi, S.2    Ohnishi, Y.3
  • 36
    • 79958062471 scopus 로고    scopus 로고
    • Identification and characterization of CdgB, a diguanylate cyclase involved in developmental processes in Streptomyces coelicolor
    • Tran, N.T., Den Hengst, C.D., Gomez-Escribano, J.P. and Buttner, M.J. (2011) Identification and characterization of CdgB, a diguanylate cyclase involved in developmental processes in Streptomyces coelicolor. J. Bacteriol., 193, 3100-3108.
    • (2011) J. Bacteriol. , vol.193 , pp. 3100-3108
    • Tran, N.T.1    Den Hengst, C.D.2    Gomez-Escribano, J.P.3    Buttner, M.J.4
  • 37
    • 26244432061 scopus 로고    scopus 로고
    • Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor
    • DOI 10.1111/j.1365-2958.2005.04817.x
    • Uguru, G.C., Stephens, K.E., Stead, J.A., Towle, J.E., Baumberg, S. and McDowall, K.J. (2005) Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor. Mol. Microbiol., 58, 131-150. (Pubitemid 41415036)
    • (2005) Molecular Microbiology , vol.58 , Issue.1 , pp. 131-150
    • Uguru, G.C.1    Stephens, K.E.2    Stead, J.A.3    Towle, J.E.4    Baumberg, S.5    McDowall, K.J.6
  • 38
    • 80052077061 scopus 로고    scopus 로고
    • The regulation of the secondary metabolism of Streptomyces: New links and experimental advances
    • van Wezel, G.P. and McDowall, K.J. (2011) The regulation of the secondary metabolism of Streptomyces: new links and experimental advances. Nat. Prod. Rep., 28, 1311-1333.
    • (2011) Nat. Prod. Rep. , vol.28 , pp. 1311-1333
    • Van Wezel, G.P.1    McDowall, K.J.2
  • 40
    • 34548390720 scopus 로고    scopus 로고
    • Statistical reconstruction of transcription factor activity using Michaelis-Menten kinetics
    • DOI 10.1111/j.1541-0420.2007.00757.x
    • Khanin, R., Vinciotti, V., Mersinias, V., Smith, C.P. and Wit, E. (2007) Statistical reconstruction of transcription factor activity using Michaelis-Menten kinetics. Biometrics, 63, 816-823. (Pubitemid 47352836)
    • (2007) Biometrics , vol.63 , Issue.3 , pp. 816-823
    • Khanin, R.1    Vinciotti, V.2    Mersinias, V.3    Smith, C.P.4    Wit, E.5
  • 41
    • 0035788803 scopus 로고    scopus 로고
    • A complex role for the γ-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2)
    • DOI 10.1046/j.1365-2958.2001.02562.x
    • Takano, E., Chakraburtty, R., Nihira, T., Yamada, Y. and Bibb, M.J. (2001) A complex role for the gamma-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2). Mol. Microbiol., 41, 1015-1028. (Pubitemid 36124699)
    • (2001) Molecular Microbiology , vol.41 , Issue.5 , pp. 1015-1028
    • Takano, E.1    Chakraburtty, R.2    Nihira, T.3    Yamada, Y.4    Bibb, M.J.5
  • 42
    • 79951818856 scopus 로고    scopus 로고
    • Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2)
    • D'Alia, D., Eggle, D., Nieselt, K., Hu, W.S., Breitling, R. and Takano, E. (2011) Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2). Microb. Biotechnol., 4, 239-251.
    • (2011) Microb. Biotechnol. , vol.4 , pp. 239-251
    • D'Alia, D.1    Eggle, D.2    Nieselt, K.3    Hu, W.S.4    Breitling, R.5    Takano, E.6
  • 43
    • 33846678395 scopus 로고    scopus 로고
    • A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2)
    • DOI 10.1007/s00203-006-0176-7
    • Pawlik, K., Kotowska, M., Chater, K.F., Kuczek, K. and Takano, E. (2007) A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2). Arch. Microbiol., 187, 87-99. (Pubitemid 46197385)
    • (2007) Archives of Microbiology , vol.187 , Issue.2 , pp. 87-99
    • Pawlik, K.1    Kotowska, M.2    Chater, K.F.3    Kuczek, K.4    Takano, E.5
  • 44
    • 77955343496 scopus 로고    scopus 로고
    • Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)
    • Gottelt, M., Kol, S., Gomez-Escribano, J.P., Bibb, M. and Takano, E. (2010) Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2). Microbiology, 156, 2343-2353.
    • (2010) Microbiology , vol.156 , pp. 2343-2353
    • Gottelt, M.1    Kol, S.2    Gomez-Escribano, J.P.3    Bibb, M.4    Takano, E.5
  • 45
    • 67651208925 scopus 로고    scopus 로고
    • Adapting the machine: Adaptor proteins for Hsp100/Clp and AAA+proteases
    • Kirstein, J., Moliere, N., Dougan, D.A. and Turgay, K. (2009) Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+proteases. Nat. Rev. Microbiol., 7, 589-599.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 589-599
    • Kirstein, J.1    Moliere, N.2    Dougan, D.A.3    Turgay, K.4
  • 46
    • 79251606265 scopus 로고    scopus 로고
    • Phosphoprotein affinity purification identifies proteins involved in S-adenosyl-L-methionine-induced enhancement of antibiotic production in Streptomyces coelicolor
    • Meng, L., Yang, S., Palaniyandi, S., Lee, S., Lee, I., Kim, T. and Suh, J. (2011) Phosphoprotein affinity purification identifies proteins involved in S-adenosyl-L-methionine-induced enhancement of antibiotic production in Streptomyces coelicolor. J. Antibiot., 64, 97-101.
    • (2011) J. Antibiot. , vol.64 , pp. 97-101
    • Meng, L.1    Yang, S.2    Palaniyandi, S.3    Lee, S.4    Lee, I.5    Kim, T.6    Suh, J.7
  • 48
    • 0037224691 scopus 로고    scopus 로고
    • Accumulation of S-adenosyl-L-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23
    • Kim, D.J., Huh, J.H., Yang, Y.Y., Kang, C.M., Lee, I.H., Hyun, C.G., Hong, S.K. and Suh, J.W. (2003) Accumulation of S-adenosyl-L-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23. J. Bacteriol., 185, 592-600.
    • (2003) J. Bacteriol. , vol.185 , pp. 592-600
    • Kim, D.J.1    Huh, J.H.2    Yang, Y.Y.3    Kang, C.M.4    Lee, I.H.5    Hyun, C.G.6    Hong, S.K.7    Suh, J.W.8
  • 49
    • 80051732583 scopus 로고    scopus 로고
    • Bacterial transcriptomics: What is beyond the RNA horiz-ome?
    • Guell, M., Yus, E., Lluch-Senar, M. and Serrano, L. (2011) Bacterial transcriptomics: what is beyond the RNA horiz-ome? Nat. Rev. Microbiol., 9, 658-669.
    • (2011) Nat. Rev. Microbiol. , vol.9 , pp. 658-669
    • Guell, M.1    Yus, E.2    Lluch-Senar, M.3    Serrano, L.4
  • 51
    • 34250619055 scopus 로고    scopus 로고
    • Genomic analysis of protein-DNA interactions in bacteria: Insights into transcription and chromosome organization
    • DOI 10.1111/j.1365-2958.2007.05781.x
    • Wade, J.T., Struhl, K., Busby, S.J. and Grainger, D.C. (2007) Genomic analysis of protein-DNA interactions in bacteria: insights into transcription and chromosome organization. Mol. Microbiol., 65, 21-26. (Pubitemid 46934493)
    • (2007) Molecular Microbiology , vol.65 , Issue.1 , pp. 21-26
    • Wade, J.T.1    Struhl, K.2    Busby, S.J.W.3    Grainger, D.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.