Principles of microbial alchemy: Insights from the Streptomyces coelicolor genome sequence

Genome Biology

Volumn 3, Issue 7, 2002, Pages

  Thompson, Charles J ^a   Fink, Doris ^a   Nguyen, Liem D ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; ACTINORHODINE; AMINO ACID; ANTIBIOTIC AGENT; ERYTHROMYCIN DERIVATIVE; MACROLIDE; PEPTIDE SYNTHASE; POLYKETIDE; POLYKETIDE SYNTHASE; POLYPEPTIDE ANTIBIOTIC AGENT; PRODIGIOSIN; RAPAMYCIN; SIDEROPHORE; TACROLIMUS;

BACTERIAL GENOME; BIOCHEMISTRY; CLASSIFICATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; GENE SEQUENCE; GENETIC LINKAGE; GENOME ANALYSIS; HISTORY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NONHUMAN; SEQUENCE ANALYSIS; SHORT SURVEY; SOIL; STREPTOMYCES; STREPTOMYCES COELICOLOR;

ANTI-BACTERIAL AGENTS; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; PIGMENTS, BIOLOGICAL; STREPTOMYCES;

BACTERIA (MICROORGANISMS); PROKARYOTA; STREPTOMYCES; STREPTOMYCES COELICOLOR;

EID: 0036380072     PISSN: 14656906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (30)

1. Miyadoh S, Hamada M, Hotta K, Kudo T, Seino A, Vobis G, Yokota A: Atlas of Actinomycetes: Tokyo: Asakura Publishing Co. Ltd.; 1997.
2. Süsstrunk U, Pidoux J, Taubert S, Ullmann A, Thompson CJ: Pleiotropic effects of cAMP on germination, antibiotic biosynthesis, and morphological development in Streptomyces coelicolor. Molec Microbiol 1998, 30:33-46.
3. Chater KF, Bibb MJ: Regulation of bacterial antibiotic production. In Products of Secondary Metabolism. Edited by Pühler A. Weinheim: VCH; 1997: 57-105.
4. Bérdy J: Are Actinomycetes exhausted as a source of secondary metabolites? Proceedings of the Ninth Symposium on the Actinomycetes 1995: 13-34.
5. Watve MG, Tickoo R, Jog MM, Bhole BD: How many antibiotics are produced by the genus Streptomyces? Arch Microbiol 2001, 176:386-390.
6. Vining LC: Functions of secondary metabolites. Annu Rev Microbiol 1990, 44:395-427.
7. Sanglier JJ, Haag H, Huck TA, Fehr T: Novel bioactive compounds from Actinomycetes: a short review (1988-1992). Res Microbiol 1993, 144:633-642.
8. Bentley SD, Chater KF, Cerdeno-Tarraga AM, Challis GL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, et al.: Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 2002, 417:141-147.
9. Zhang YX, Perry K, Vinci VA, Powell K, Stemmer WP, del Cardayre SB: Genome shuffling leads to rapid phenotypic improvement in bacteria. Nature 2002, 415:644-646.
10. Hopwood DA: Genetic contributions to understanding polyketide synthases. Chem Rev 1997, 97:2465-2498.
11. Hutchinson CR: Microbial polyketide synthases: more and more prolific. Proc Natl Acad Sci USA 1999, 96:3336-3338.
12. Cane DE, Walsh CT, Khosla C: Harnessing the biosynthetic code: combinations, permutations, and mutations. Science 1998, 282:63-68.
13. Staunton J, Wilkinson B: Combinatorial biosynthesis of polyketides and nonribosomal peptides. Curr Opin Chem Biol 2001, 5:159-164.
14. Stachelhaus T, Schneider A, Marahiel MA: Rational design of peptide antibiotics by targeted replacement of bacterial and fungal domains. Science 1995, 269:69-72.
15. Leadlay PF: Combinatorial approaches to polyketide biosynthesis. Curr Opin Chem Biol 1997, 1:162-168.
16. McDaniel R, Thamchaipenet A, Gustafsson C, Fu H, Betlach M, Ashley G: Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products. Proc Natl Acad Sci USA 1999, 96:1846-1851.
17. Omura S, Ikeda H, Ishikawa J, Hanamoto A, Takahashi C, Shinose M, Takahashi Y, Horikawa H, Nakazawa H, Osonoe T, et al.: Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites. Proc Natl Acad Sci USA 2001, 98:12215-12220.
18. Hara O, Murakami T, Imai S, Anzai H, Itoh R, Kumada Y, Takano E, Satoh E, Satoh A, Nagaoka K, Thompson C: The bialaphos biosynthetic genes of Streptomyces viridochromogenes: cloning, heterospecific expression, and comparison with the genes of Streptomyces hygroscopicus. J Gen Microbiol 1991, 137:351-359.
19. Friend EJ, Hopwood DA: The linkage map of Streptomyces rimosus. J Gen Microbiol 1971, 68:187-197.
20. Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE, 3rd, et al.: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998, 393:537-544.
21. Cole ST, Eiglmeier K, Parkhill J, James KD, Thomson NR, Wheeler PR, Honore N, Garnier T, Churcher C, Harris D, et al.: Massive gene decay in the leprosy bacillus. Nature 2001, 409:1007-1011.
22. George KM, Chatterjee D, Gunawardana G, Welty D, Hayman J, Lee R, Small PL: Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence. Science 1999, 283:854-857.
23. Quadri LE, Sello J, Keating TA, Weinreb PH, Walsh CT: Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin. Chem Biol 1998, 5:631-645.
24. Umezawa H: Low-molecular-weight immunomodifiers produced by microorganisms. Biotechnol Genet Eng Rev 1985, 3:255-273.
25. Goto T, Kino T, Hatanaka H, Nishiyama M, Okuhara M, Kohsaka M, Aoki H, Imanaka H: Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. Transplant Proc 1987, 19:4-8.
26. Vezina C, Kudelski A, Sehgal SN: Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot (Tokyo) 1975, 28:721-726.
27. Holt TG, Chang C, Laurent-Winter C, Murakami T, Garrels JI, Davies JE, Thompson CJ: Global changes in gene expression related to antibiotic synthesis in Streptomyces hygroscopicus. Mol Microbiol 1992, 6:969-980.
28. Vohradsky J, Li XM, Dale G, Folcher M, Nguyen L, Viollier PH, Thompson CJ: Developmental control of stress stimulons in Streptomyces coelicolor revealed by statistical analyses of global gene expression patterns. J Bacteriol 2000, 182:4979-4986.
29. SWICZ: Swiss - Czech Proteomics Server [http://proteom.biomed.cas.cz]
30. Huang J, Lih CJ, Pan KH, Cohen SN: Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays. Genes Dev 2001, 15:3183-3192.