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Volumn 26, Issue 3, 2012, Pages 313-318

Role of TH17 in the pathogenesis of cutaneous inflammatory diseases

Author keywords

Allergic contact dermatitis; Atopic dermatitis; IL 17; Psoriasis; Th17

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; AIN 648; BRODALUMAB; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR6; GAMMA INTERFERON; HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN E; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 19; INTERLEUKIN 22; INTERLEUKIN 23; IXEKIZUMAB; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; NICKEL; PLACEBO; RG 4934; SECUKINUMAB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84868157684     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (40)

References (40)
  • 1
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Romagnani S. The Th1/Th2 paradigm. Immunol Today 1997; 18(6):263-6. (Pubitemid 27261442)
    • (1997) Immunology Today , vol.18 , Issue.6 , pp. 263-266
    • Romagnani, S.1
  • 2
    • 27544490377 scopus 로고    scopus 로고
    • + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • DOI 10.1038/ni1254, PII N1254
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6(11):1123-32. (Pubitemid 41541790)
    • (2005) Nature Immunology , vol.6 , Issue.11 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 3
    • 0027215897 scopus 로고
    • CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus Saimiri gene
    • Rouvier E, Luciani MF, Mattei MG, Denizot F, Golstein P. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a Herpes virus Saimiri gene. J Immunol 1993; 150:5445-5456. (Pubitemid 23180658)
    • (1993) Journal of Immunology , vol.150 , Issue.12 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.-F.2    Mattei, M.-G.3    Denizot, F.4    Golstein, P.5
  • 5
    • 33745873727 scopus 로고    scopus 로고
    • A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
    • DOI 10.1084/jem.20060285
    • Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucialrole for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 2006; 203(7):1685-91. (Pubitemid 44036274)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.7 , pp. 1685-1691
    • Sutton, C.1    Brereton, C.2    Keogh, B.3    Mills, K.H.G.4    Lavelle, E.C.5
  • 6
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • DOI 10.1074/jbc.M207577200
    • Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003; 278:1910-14. (Pubitemid 36801431)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.3 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.-H.3    De Sauvage, F.J.4    Gurney, A.L.5
  • 7
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 proteinen gages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B, et al. Novel p19 proteinen gages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13(5):715-25.
    • (2000) Immunity , vol.13 , Issue.5 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 8
    • 0032939560 scopus 로고    scopus 로고
    • IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFN-gamma and TNF-alpha
    • Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J Immunol 1999; 162:494-502. (Pubitemid 29018959)
    • (1999) Journal of Immunology , vol.162 , Issue.1 , pp. 494-502
    • Albanesi, C.1    Cavani, A.2    Girolomoni, G.3
  • 9
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, Homma I, Sekikawa K, Asano M, Iwakura Y. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002; 17(3):375-87.
    • (2002) Immunity , vol.17 , Issue.3 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3    Sudo, K.4    Iwase, M.5    Homma, I.6    Sekikawa, K.7    Asano, M.8    Iwakura, Y.9
  • 10
    • 33750815930 scopus 로고    scopus 로고
    • + IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses
    • He D, Wu L, Kim HK, Li H, Elmets CA, Xu H.CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 2006; 177(10):6852-8. (Pubitemid 44715050)
    • (2006) Journal of Immunology , vol.177 , Issue.10 , pp. 6852-6858
    • He, D.1    Wu, L.2    Kim, H.K.3    Li, H.4    Elmets, C.A.5    Xu, H.6
  • 12
    • 69449095507 scopus 로고    scopus 로고
    • IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th 17-related cytokines
    • Ortega C, Fernández-A S, Carrillo JM, Romero P, Molina IJ, Moreno JC, Santamaria M. IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th 17-related cytokines. J Leukoc Biol 2009; 86(2):435-43.
    • (2009) J Leukoc Biol , vol.86 , Issue.2 , pp. 435-443
    • Ortega, C.1    Fernández-A, S.2    Carrillo, J.M.3    Romero, P.4    Molina, I.J.5    Moreno, J.C.6    Santamaria, M.7
  • 13
    • 69949142054 scopus 로고    scopus 로고
    • Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis
    • Caruso R, Botti E, Sarra M, et al. Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis. Nat Med 2009; 15(9):1013-5.
    • (2009) Nat Med , vol.15 , Issue.9 , pp. 1013-1015
    • Caruso, R.1    Botti, E.2    Sarra, M.3
  • 15
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
    • Wolk K, Witte E, Wallace E, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006; 36(5):1309-23.
    • (2006) Eur J Immunol , vol.36 , Issue.5 , pp. 1309-1323
    • Wolk, K.1    Witte, E.2    Wallace, E.3
  • 16
    • 27644565806 scopus 로고    scopus 로고
    • Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity
    • DOI 10.1155/MI.2005.273, PII S0962935105507075
    • Arican O, Aral M, Sasmaz S, Ciragil P. Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm 2005; 2005(5):273-9. (Pubitemid 41577417)
    • (2005) Mediators of Inflammation , vol.2005 , Issue.5 , pp. 273-279
    • Arican, O.1    Aral, M.2    Sasmaz, S.3    Ciragil, P.4
  • 19
    • 43449111187 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
    • DOI 10.1016/S0140-6736(08)60725-4, PII S0140673608607254
    • Leonardi CL, Kimball AB, Papp KA, et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double blind, placebo-controlled trial (PHOENIX 1). Lancet 2008; 371:1665-74. (Pubitemid 351671883)
    • (2008) The Lancet , vol.371 , Issue.9625 , pp. 1665-1674
    • Leonardi, C.L.1    Kimball, A.B.2    Papp, K.A.3    Yeilding, N.4    Guzzo, C.5    Wang, Y.6    Li, S.7    Dooley, L.T.8    Gordon, K.B.9
  • 20
    • 84859017988 scopus 로고    scopus 로고
    • Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
    • Papp KA, Leonardi C, Menter A, et al. Brodalumab, an anti-interleukin-17- receptor antibody for psoriasis. N Engl J Med 2012; 366(13):1181-9.
    • (2012) N Engl J Med , vol.366 , Issue.13 , pp. 1181-1189
    • Papp, K.A.1    Leonardi, C.2    Menter, A.3
  • 22
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • Hueber W, Patel DD, Dryja T, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2010; 2(52):52ra72.
    • (2010) Sci Transl Med , vol.2 , Issue.52
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3
  • 23
    • 84872594863 scopus 로고    scopus 로고
    • Secukinumab efficacy and safety preliminary results from a phase II subcutaneous dose-ranging study in the treatment of moderate-to-severe plaque psoriasis
    • Presented at: Oral presentation FC01.5
    • Papp KA, et al. 'Secukinumab efficacy and safety preliminary results from a phase II subcutaneous dose-ranging study in the treatment of moderate-to-severe plaque psoriasis.' Presented at: 20th Congress of the European Academy of Dermatology and Venereology; 20-24 October, 2011; Lisbon, Portugal. Oral presentation FC01.5.
    • 20th Congress of the European Academy of Dermatology and Venereology; 20-24 October, 2011; Lisbon, Portugal.
    • Papp, K.A.1
  • 24
    • 84872601512 scopus 로고    scopus 로고
    • Secukinumab, a novel fully human antibody to interleukin-17A, in the treatment of moderate-to-severe plaque psoriasis: Efficacy and safety interim results from a phase II intravenous induction dose-ranging study
    • Presented at: Oral presentation FC01.7
    • Papp KA, et al. 'Secukinumab, a novel fully human antibody to interleukin-17A, in the treatment of moderate-to-severe plaque psoriasis: Efficacy and safety interim results from a phase II intravenous induction dose-ranging study.' Presented at: 20th Congress of the European Academy of Dermatology and Venereology; 20-24 October, 2011; Lisbon, Portugal. Oral presentation FC01.7.
    • 20th Congress of the European Academy of Dermatology and Venereology; 20-24 October, 2011; Lisbon, Portugal
    • Papp, K.A.1
  • 25
    • 71149092070 scopus 로고    scopus 로고
    • Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis
    • Guttman-Yassky E, Suárez-Fariñas M, Chiricozzi A, et al. Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis. J Allergy Clin Immunol 2009; 124(6):1235-1244.
    • (2009) J Allergy Clin Immunol , vol.124 , Issue.6 , pp. 1235-1244
    • Guttman-Yassky, E.1    Suárez-Fariñas, M.2    Chiricozzi, A.3
  • 27
    • 67649161002 scopus 로고    scopus 로고
    • IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells
    • Nograles KE, Zaba LC, Shemer A, et al. IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells. J Allergy Clin Immunol 2009; 123(6):1244-52.
    • (2009) J Allergy Clin Immunol , vol.123 , Issue.6 , pp. 1244-1252
    • Nograles, K.E.1    Zaba, L.C.2    Shemer, A.3
  • 37
    • 58149198187 scopus 로고    scopus 로고
    • Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis
    • Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, et al. Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J Immunol 2008; 181(10):7420-7.
    • (2008) J Immunol , vol.181 , Issue.10 , pp. 7420-7427
    • Guttman-Yassky, E.1    Lowes, M.A.2    Fuentes-Duculan, J.3
  • 38
    • 77649244202 scopus 로고    scopus 로고
    • Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses
    • Nograles KE, Suárez-Fariñas M, Shemer A, et al. Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses. J Allergy Clin Immunol 2010; 125(3):744-6, 746.e1-746.e2.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.3
    • Nograles, K.E.1    Suárez-Fariñas, M.2    Shemer, A.3
  • 39
    • 0036907174 scopus 로고    scopus 로고
    • The chemokine receptor CCR6 identifies interferon-gamma expressing T cells and is decreased in atopic dermatitis as compared with psoriasis
    • DOI 10.1046/j.1523-1747.2002.19624.x
    • Ong PY, Leung DY. The chemokine receptor CCR6 identifies interferon-gamma expressing T cells and is decreased in atopic dermatitis as compared with psoriasis. J Invest Dermatol 2002; 119(6):1463-4. (Pubitemid 36005636)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.6 , pp. 1463-1464
    • Leung, D.Y.M.1    Ong, P.Y.2
  • 40
    • 0036547277 scopus 로고    scopus 로고
    • Expression of the C-C chemokine MIP-3alpha/CCL20 in human epidermis with impaired permeability barrier function
    • DOI 10.1034/j.1600-0625.2002.110205.x
    • Schmuth M, Neyer S, Rainer C, Grassegger A, Fritsch P, Romani N, Heufler C. Expression of the C-C chemokine MIP-3 alpha/CCL20 in human epidermis with impaired permeability barrier function. Exp Dermatol 2002; 11(2):135-42. (Pubitemid 36934631)
    • (2002) Experimental Dermatology , vol.11 , Issue.2 , pp. 135-142
    • Schmuth, M.1    Neyer, S.2    Rainer, C.3    Grassegger, A.4    Fritsch, P.5    Romani, N.6    Heufler, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.