Are bipolar disorders underdiagnosed in patients with depressive episodes? Results of the multicenter BRIDGE screening study in Germany

Journal of Affective Disorders

Volumn 142, Issue 1-3, 2012, Pages 45-52

  Bschor, T ^a,b   Angst, J ^c   Azorin, J M ^d   Bowden, C L ^e   Perugi, G ^f   Vieta, E ^g   Young, A H ^h   Kruger S ⁱ  

^a Schlosspark Clinic   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d HÔPITAL SAINTE MARGUERITE   (France)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^f UNIVERSITY OF PISA   (Italy)

^g UNIVERSITY OF BARCELONA   (Spain)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

ⁱ Vivantes Humboldt Clinic   (Germany)

Author keywords

Bipolar disorder; Diagnostic criteria; Hypomania; Major depression; Mania

Indexed keywords

ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; LITHIUM; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; VALPROIC ACID;

ADULT; AGED; ALGORITHM; ARTICLE; BIPOLAR DISORDER; BIPOLAR II DISORDER; CLINICAL ASSESSMENT TOOL; DSM-IV; FEMALE; GERMANY; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MANIA; MOOD DISORDER; MULTICENTER STUDY; PHYSICIAN; PREVALENCE; PRIORITY JOURNAL; PUERPERAL DEPRESSION; SOCIAL STATUS; SUICIDE ATTEMPT;

ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; ANTIDEPRESSIVE AGENTS; BIPOLAR DISORDER; CHECKLIST; COMORBIDITY; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIAGNOSTIC ERRORS; FEMALE; GERMANY; HUMANS; MALE; MIDDLE AGED; PREVALENCE; YOUNG ADULT;

EID: 84868143855     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2012.03.042     Document Type: Article

References (52)

1. I.H. Aas Global Assessment of Functioning (GAF): properties and frontier of current knowledge Annals of General Psychiatry 9 2010 20
2. H.S. Akiskal, K.K. Akiskal, S. Lancrenon, E.G. Hantouche, J.P. Fraud, C. Gury, and J.F. Allilaire Validating the bipolar spectrum in the French National EPIDEP Study: overview of the phenomenology and relative prevalence of its clinical prototypes Journal of Affective Disorders 96 2006 197 205
3. J.F. Allilaire, E.G. Hantouche, D. Sechter, M.L. Bourgeois, J.M. Azorin, S. Lancrenon, L. Chatenet-Duchene, and H.S. Akiskal Frequency and clinical aspects of bipolar II disorder in a French multicenter study: EPIDEP Encephale 27 2001 149 158
4. J. Angst, R. Adolfsson, F. Benazzi, A. Gamma, E. Hantouche, T.D. Meyer, P. Skeppar, E. Vieta, and J. Scott The HCL-32: towards a self-assessment tool for hypomanic symptoms in outpatients Journal of Affective Disorders 88 2005 217 233
5. J. Angst, J.M. Azorin, C.L. Bowden, G. Perugi, E. Vieta, A. Gamma, and A.H. Young Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study Archives of General Psychiatry 68 2011 791 798
6. J. Angst, L. Cui, J. Swendsen, S. Rothen, A. Cravchik, R.C. Kessler, and K.R. Merikangas Major depressive disorder with subthreshold bipolarity in the National Comorbidity Survey Replication The American Journal of Psychiatry 167 2010 1194 1201
7. J. Angst, A. Gamma, F. Benazzi, V. Ajdacic, D. Eich, and W. Rossler Diagnostic issues in bipolar disorder European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology 13 Suppl 2 2003 S43 50
8. J. Angst, A. Gamma, F. Benazzi, V. Ajdacic, D. Eich, and W. Rossler Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania Journal of Affective Disorders 73 2003 133 146
9. APA, 2012. American Psychiatric Association: DSM-5: The future of psychiatric diagnosis.
10. Azorin, J.M.; Angst, J.; Gamma, A.; Bowden, C.L.; Perugi, G.; Vieta, E.; Young, A.; 2011. Identifying features of bipolarity in patients with first-episode postpartum depression: Findings from the international BRIDGE study. Journal of Affective Disorders
11. C. Baethge, M.N. Smolka, P. Gruschka, A. Berghofer, P. Schlattmann, M. Bauer, L. Altshuler, P. Grof, and B. Muller-Oerlinghausen Does prophylaxis-delay in bipolar disorder influence outcome? Results from a long-term study of 147 patients Acta Psychiatrica Scandinavica 107 2003 260 267
12. C. Baethge, L. Tondo, I.M. Bratti, T. Bschor, M. Bauer, A.C. Viguera, and R.J. Baldessarini Prophylaxis latency and outcome in bipolar disorders Canadian Journal of Psychiatry Revue Canadienne De Psychiatrie 48 2003 449 457
13. R.J. Baldessarini, E. Vieta, J.R. Calabrese, M. Tohen, and C.L. Bowden Bipolar depression: overview and commentary. Harvard Review of Psychiatry 18 2010 143 157
14. M. Bauer, T. Bschor, A. Pfennig, P.C. Whybrow, J. Angst, M. Versiani, and H.J. Moller World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders in primary care. World Journal of Biological Psychiatry 8 2007 67 104
15. M. Bauer, and A. Pfennig Epidemiology of bipolar disorders. Epilepsia 46 Suppl 4 2005 8 13
16. F. Benazzi Bipolar disorder - focus on bipolar II disorder and mixed depression Lancet 369 2007 935 945
17. T. Bschor Therapy resistant bipolar depression [book chapter in German] T. Bschor, Manual of therapy resistant depression. Pharmacotherapy - Somatic therapy - Psychotherapy 2008 Kohlhammer Stuttgart 165 182
18. M.G. Carta, M.C. Hardoy, M. Cadeddu, A. Murru, A. Campus, P.L. Morosini, A. Gamma, and J. Angst The accuracy of the Italian version of the Hypomania Checklist (HCL-32) for the screening of bipolar disorders and comparison with the Mood Disorder Questionnaire (MDQ) in a clinical sample. Clinical Practice and Epidemiology in Mental Health 2 2 2006
19. F. Colom, and E. Vieta The road to DSM-V. Bipolar disorder episode and course specifiers Psychopathology 42 2009 209 218
20. C.A. Demeter, L.D. Townsend, M. Wilson, and R.L. Findling Current research in child and adolescent bipolar disorder Dialogues in Clinical Neuroscience 10 2008 215 228
21. DGPPN, B.; KBV, AWMF, AkdÄ, BPtK, BApK, DAGSHG, DEGAM, DGPM, DGPs, DGRW (eds.) for the Guideline Group on Unipolar Depression, 2009. S3-Guideline/National Disease Management Guideline Unipolar Depression. DGPPN, ÄZQ, AWMF, Berlin, Düsseldorf.
22. M.A. Frye Clinical practice. Bipolar disorder - a focus on depression The New England Journal of Medicine 364 2011 51 59
23. S.N. Ghaemi, E.E. Boiman, and F.K. Goodwin Diagnosing bipolar disorder and the effect of antidepressants: a naturalistic study The Journal of Clinical Psychiatry 61 2000 804 808
24. J.F. Goldberg, R.H. Perlis, C.L. Bowden, M.E. Thase, D.J. Miklowitz, L.B. Marangell, J.R. Calabrese, A.A. Nierenberg, and G.S. Sachs Manic symptoms during depressive episodes in 1380 patients with bipolar disorder: findings from the STEP-BD. The American Journal of Psychiatry 166 2009 173 181
25. G.M. Goodwin Evidence-based guidelines for treating bipolar disorder: revised second edition - recommendations from the British Association for Psychopharmacology Journal of Psychopharmacology (Oxford, England) 23 2009 346 388
26. H. Grunze, E. Vieta, G.M. Goodwin, C. Bowden, R.W. Licht, H.J. Moller, and S. Kasper The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2010 on the treatment of acute bipolar depression World Journal of Biological Psychiatry 11 2010 81 109
27. R.M. Hirschfeld, J.R. Calabrese, M.M. Weissman, M. Reed, M.A. Davies, M.A. Frye, P.E. Keck Jr.; L. Lewis, S.L. McElroy, J.P. McNulty, and K.D. Wagner Screening for bipolar disorder in the community The Journal of Clinical Psychiatry 64 2003 53 59
28. R.M. Hirschfeld, L. Lewis, and L.A. Vornik Perceptions and impact of bipolar disorder: how far have we really come? Results of the national depressive and manic-depressive association 2000 survey of individuals with bipolar disorder The Journal of Clinical Psychiatry 64 2003 161 174
29. R.M. Hirschfeld, J.B. Williams, R.L. Spitzer, J.R. Calabrese, L. Flynn, P.E. Keck Jr.; L. Lewis, S.L. McElroy, R.M. Post, D.J. Rapport, J.M. Russell, G.S. Sachs, and J. Zajecka Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire American Journal of Psychiatry 157 2000 1873-1875
30. M. Holtmann, F. Portner, E. Duketis, H.H. Flechtner, J. Angst, and G. Lehmkuhl Validation of the Hypomania Checklist (HCL-32) in a nonclinical sample of German adolescents Journal of Adolescence 32 2009 1075 1088
31. L.L. Judd, and H.S. Akiskal The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases Journal of Affective Disorders 73 2003 123 131
32. L.L. Judd, H.S. Akiskal, P.J. Schettler, W. Coryell, J. Endicott, J.D. Maser, D.A. Solomon, A.C. Leon, and M.B. Keller A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder Archives of General Psychiatry 60 2003 261 269
33. L.L. Judd, H.S. Akiskal, P.J. Schettler, J. Endicott, J. Maser, D.A. Solomon, A.C. Leon, J.A. Rice, and M.B. Keller The long-term natural history of the weekly symptomatic status of bipolar I disorder Archives of General Psychiatry 59 2002 530 537
34. R.C. Kessler, P. Berglund, O. Demler, R. Jin, K.R. Merikangas, and E.E. Walters Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication Archives of General Psychiatry 62 2005 593 602
35. R.W. Kupka, L.L. Altshuler, W.A. Nolen, T. Suppes, D.A. Luckenbaugh, G.S. Leverich, M.A. Frye, P.E. Keck Jr.; S.L. McElroy, H. Grunze, and R.M. Post Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder Bipolar Disorders 9 2007 531 535
36. J.J. Levitt, and M.T. Tsuang The heterogeneity of schizoaffective disorder: implications for treatment The American Journal of Psychiatry 145 1988 926 936
37. J.D. Lish, S. Dime-Meenan, P.C. Whybrow, R.A. Price, and R.M. Hirschfeld The National Depressive and Manic-depressive Association (DMDA) survey of bipolar members Journal of Affective Disorders 31 1994 281 294
38. E.R. Maniscalco, and V. Hamrin Assessment and diagnostic issues in pediatric bipolar disorder Archives of Psychiatric Nursing 22 2008 344 355
39. A. Martinez-Aran, E. Vieta, C. Torrent, J. Sanchez-Moreno, J.M. Goikolea, M. Salamero, G.S. Malhi, A. Gonzalez-Pinto, C. Daban, S. Alvarez-Grandi, K. Fountoulakis, G. Kaprinis, R. Tabares-Seisdedos, and J.L. Ayuso-Mateos Functional outcome in bipolar disorder: the role of clinical and cognitive factors Bipolar Disorders 9 2007 103 113
40. K.R. Merikangas, H.S. Akiskal, J. Angst, P.E. Greenberg, R.M. Hirschfeld, M. Petukhova, and R.C. Kessler Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication Archives of General Psychiatry 64 2007 543 552
41. T.D. Meyer, P. Hammelstein, L.G. Nilsson, P. Skeppar, R. Adolfsson, and J. Angst The Hypomania Checklist (HCL-32): its factorial structure and association to indices of impairment in German and Swedish nonclinical samples Comprehensive Psychiatry 48 2007 79 87
42. B. Muller-Oerlinghausen, A. Berghofer, and M. Bauer Bipolar disorder Lancet 359 2002 241 247
43. NICE - National Collaborating Centre for Mental Health, 2009. Depression. The treatment and management of depression in adults NICE clinical guideline.
44. W.A. Nolen, and D. Bloemkolk Treatment of bipolar depression, a review of the literature and a suggestion for an algorithm Neuropsychobiology 42 Suppl 1 2000 11 17
45. M.L. Phillips, and E. Frank Redefining bipolar disorder: toward DSM-V. The American Journal of Psychiatry 163 2006 1135 1136
46. D.C. Rettew, A.D. Lynch, T.M. Achenbach, L. Dumenci, and M.Y. Ivanova Meta-analyses of agreement between diagnoses made from clinical evaluations and standardized diagnostic interviews International Journal of Methods in Psychiatric Research 18 2009 169 184
47. G.S. Sachs, A.A. Nierenberg, J.R. Calabrese, L.B. Marangell, S.R. Wisniewski, L. Gyulai, E.S. Friedman, C.L. Bowden, M.D. Fossey, M.J. Ostacher, T.A. Ketter, J. Patel, P. Hauser, D. Rapport, J.M. Martinez, M.H. Allen, D.J. Miklowitz, M.W. Otto, E.B. Dennehy, and M.E. Thase Effectiveness of adjunctive antidepressant treatment for bipolar depression. The New England Journal of Medicine 356 2007 1711 1722
48. D.J. Smith, E. Griffiths, M. Kelly, K. Hood, N. Craddock, and S.A. Simpson Unrecognised bipolar disorder in primary care patients with depression The British Journal of Psychiatry: the Journal of Mental Science 199 2011 49 56
49. E. Vieta, and M.L. Phillips Deconstructing bipolar disorder: a critical review of its diagnostic validity and a proposal for DSM-V and ICD-11 Schizophrenia Bulletin 33 2007 886 892
50. E. Vieta, J. Sanchez-Moreno, A. Bulbena, L. Chamorro, J.L. Ramos, J. Artal, F. Perez, M.A. Oliveras, J. Valle, J. Lahuerta, and J. Angst Cross validation with the mood disorder questionnaire (MDQ) of an instrument for the detection of hypomania in Spanish: the 32 item hypomania symptom check list (HCL-32) Journal of Affective Disorders 101 2007 43 55
51. Yatham, L.N.; Kennedy, S.H.; Schaffer, A.; Parikh, S.V.; Beaulieu, S.; O'Donovan, C.; MacQueen, G.; McIntyre, R.S.; Sharma, V.; Ravindran, A.; Young, L.T.; Young, A.H.; Alda, M.; Milev, R.; Vieta, E.; Calabrese, J.R.; Berk, M.; Ha, K.; Kapczinski, F.; 2009. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009. Bipolar Disorders 11, 225-255.
52. P. Zimmermann, T. Bruckl, A. Nocon, H. Pfister, R. Lieb, H.U. Wittchen, F. Holsboer, and J. Angst Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity Archives of General Psychiatry 66 2009 1341 1352