Alzheimer disease family history impacts resting state functional connectivity

Annals of Neurology

Volumn 72, Issue 4, 2012, Pages 571-577

  Wang, Liang ^a   Roe, Catherine M ^a   Snyder, Abraham Z ^a,b   Brier, Matthew R ^a   Thomas, Jewell B ^a   Xiong, Chengjie ^a,c   Benzinger, Tammie L ^a,b   Morris, John C ^a   Ances, Beau M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E4;

ADULT; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEFAULT MODE NETWORK; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; FAMILY HISTORY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MALE; MIDDLE TEMPORAL GYRUS; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NETWORK; ONSET AGE; POSTERIOR CINGULATE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; TEMPORAL CORTEX;

AGE OF ONSET; AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; COGNITION; DNA; EDUCATIONAL STATUS; ENTORHINAL CORTEX; FAMILY; FEMALE; GENOTYPE; HETEROZYGOTE; HIPPOCAMPUS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; REST; TEMPORAL LOBE;

EID: 84868128295     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23643     Document Type: Article

References (46)

1. Thies W, Bleiler L,. 2011 Alzheimer's disease facts and figures. Alzheimers Dement 2011; 7: 208-244.
2. Gatz M, Reynolds CA, Fratiglioni L, et al. Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry 2006; 63: 168-174.
3. Tanzi RE, Bertram L,. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 2005; 120: 545-555.
4. Campion D, Dumanchin C, Hannequin D, et al. Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum. Am J Hum Genet 1999; 65: 664-670.
5. Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993; 43: 1467-1472.
6. Daw EW, Payami H, Nemens EJ, et al. The number of trait loci in late-onset Alzheimer disease. Am J Hum Genet 2000; 66: 196-204.
7. Harold D, Abraham R, Hollingworth P, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 2009; 41: 1088-1093.
8. Lambert JC, Heath S, Even G, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 2009; 41: 1094-1099.
9. Bird TD,. Genetic factors in Alzheimer's disease. N Engl J Med 2005; 352: 862-864.
10. Green RC, Cupples LA, Go R, et al. Risk of dementia among white and African American relatives of patients with Alzheimer disease. JAMA 2002; 287: 329-336.
11. Cupples LA, Farrer LA, Sadovnick AD, et al. Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study. Genet Med 2004; 6: 192-196.
12. Huang W, Qiu C, von Strauss E, et al. APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study. Arch Neurol 2004; 61: 1930-1934.
13. Zintl M, Schmitz G, Hajak G, Klunemann HH,. ApoE genotype and family history in patients with dementia and cognitively intact spousal controls. Am J Alzheimers Dis Other Demen 2009; 24: 349-352.
14. Donix M, Burggren AC, Suthana NA, et al. Family history of Alzheimer's disease and hippocampal structure in healthy people. Am J Psychiatry 2010; 167: 1399-1406.
15. Honea RA, Swerdlow RH, Vidoni ED, et al. Reduced gray matter volume in normal adults with a maternal family history of Alzheimer disease. Neurology 2010; 74: 113-120.
16. Honea RA, Swerdlow RH, Vidoni ED, Burns JM,. Progressive regional atrophy in normal adults with a maternal history of Alzheimer disease. Neurology 2011; 76: 822-829.
17. Johnson SC, Schmitz TW, Trivedi MA, et al. The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation. J Neurosci 2006; 26: 6069-6076.
18. Xu G, McLaren DG, Ries ML, et al. The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. Brain 2009; 132 (pt 2): 383-391.
19. Mosconi L, Brys M, Switalski R, et al. Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism. Proc Natl Acad Sci U S A 2007; 104: 19067-19072.
20. Mosconi L, Rinne JO, Tsui WH, et al. Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's. Proc Natl Acad Sci U S A 2010; 107: 5949-5954.
21. Raichle ME, MacLeod AM, Snyder AZ, et al. A default mode of brain function. Proc Natl Acad Sci U S A 2001; 98: 676-682.
22. Buckner RL, Andrews-Hanna JR, Schacter DL,. The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci 2008; 1124: 1-38.
23. Greicius MD, Srivastava G, Reiss AL, Menon V,. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A 2004; 101: 4637-4642.
24. Sorg C, Riedl V, Muhlau M, et al. Selective changes of resting-state networks in individuals at risk for Alzheimer's disease. Proc Natl Acad Sci U S A 2007; 104: 18760-18765.
25. Berg L, McKeel DW Jr, Miller JP, et al. Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 1998; 55: 326-335.
26. Xiong C, Roe CM, Buckles V, et al. Role of family history for Alzheimer biomarker abnormalities in the adult children study. Arch Neurol 2011; 68: 1313-1319.
27. Morris JC,. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993; 43: 2412-2414.
28. Morris JC, Weintraub S, Chui HC, et al. The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers. Alzheimer Dis Assoc Disord 2006; 20: 210-216.
29. Pastor P, Roe CM, Villegas A, et al. Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred. Ann Neurol 2003; 54: 163-169.
30. Fox MD, Zhang D, Snyder AZ, Raichle ME,. The global signal and observed anticorrelated resting state brain networks. J Neurophysiol 2009; 101: 3270-3283.
31. Hedden T, Van Dijk KR, Becker JA, et al. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. J Neurosci 2009; 29: 12686-12694.
32. Sheline YI, Raichle ME, Snyder AZ, et al. Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry 2010; 67: 584-587.
33. Sheline YI, Morris JC, Snyder AZ, et al. APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Abeta42. J Neurosci 2010; 30: 17035-17040.
34. Vogt BA, Pandya DN,. Cingulate cortex of the rhesus-monkey. 2. Cortical afferents. J Comp Neurol 1987; 262: 271-289.
35. Parvizi J, Van Hoesen GW, Buckwalter J, Damasio A,. Neural connections of the posteromedial cortex in the macaque. Proc Natl Acad Sci U S A 2006; 103: 1563-1568.
36. Greicius MD, Supekar K, Menon V, Dougherty RF,. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex 2009; 19: 72-78.
37. Concha L, Gross DW, Beaulieu C,. Diffusion tensor tractography of the limbic system. AJNR Am J Neuroradiol 2005; 26: 2267-2274.
38. Wang L, Laviolette P, O'Keefe K, et al. Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older individuals. Neuroimage 2010; 51: 910-917.
39. Braak H, Braak E,. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239-259.
40. Wang L, Zang Y, He Y, et al. Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. Neuroimage 2006; 31: 496-504.
41. Sperling RA, Laviolette PS, O'Keefe K, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 2009; 63: 178-188.
42. Filippini N, MacIntosh BJ, Hough MG, et al. Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc Natl Acad Sci U S A 2009; 106: 7209-7214.
43. Machulda MM, Jones DT, Vemuri P, et al. Effect of APOE epsilon4 status on intrinsic network connectivity in cognitively normal elderly subjects. Arch Neurol 2011; 68: 1131-1136.
44. Trachtenberg AJ, Filippini N, Ebmeier KP, et al. The effects of APOE on the functional architecture of the resting brain. Neuroimage 2012; 59: 565-572.
45. Westlye ET, Lundervold A, Rootwelt H, et al. Increased hippocampal default mode synchronization during rest in middle-aged and elderly APOE epsilon4 carriers: relationships with memory performance. J Neurosci 2011; 31: 7775-7783.
46. Bertram L, Lill CM, Tanzi RE,. The genetics of Alzheimer disease: back to the future. Neuron 2010; 68: 270-281.