Visualizing feasible operating ranges within tissue engineering systems using a "windows of operation" approach: A perfusion-scaffold bioreactor case study

Biotechnology and Bioengineering

Volumn 109, Issue 12, 2012, Pages 3161-3171

  Mccoy, Ryan J ^a,b   O'Brien, Fergal J ^a,b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Collagen scaffolds; Perfusion bioreactor; Tissue engineering; Windows of operation

Indexed keywords

BIO-PROCESSING INDUSTRIES; BIOREACTOR SYSTEM; BONE TISSUE ENGINEERING; CELL DETACHMENT; CELL SOURCES; COLLAGEN SCAFFOLDS; CYCLOOXYGENASE 2; ENGINEERING SYSTEMS; GENE EXPRESSION LEVELS; MARKET PLACE; MULTIVARIATE SYSTEMS; OPERATING RANGES; OPERATING VARIABLES; OSTEOGENESIS; OSTEOGENIC DIFFERENTIATION; OSTEOPONTIN; PERFORMANCE CRITERION; PERFUSION BIOREACTOR; PERFUSION BIOREACTOR SYSTEMS; SURROGATE INDICATORS; TISSUE ENGINEERS; TISSUE FORMATION;

BIOREACTORS; CELLS; COMMERCE; CYTOLOGY; GENE EXPRESSION; PORE SIZE; RESEARCH; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

BIOMATERIAL; COLLAGEN; CYCLOOXYGENASE 2; OSTEOPONTIN;

ANIMAL CELL; ARTICLE; BIOENGINEERING; BIOREACTOR; BIOTECHNOLOGY; BONE DEVELOPMENT; BONE REMODELING; CELL DIFFERENTIATION; GENE EXPRESSION; NONHUMAN; OSTEOBLAST; SHEAR STRESS; TISSUE ENGINEERING;

ANALYSIS OF VARIANCE; ANIMALS; BIOREACTORS; CELL DIFFERENTIATION; CELL LINE; COLLAGEN; COMPUTATIONAL BIOLOGY; CYCLOOXYGENASE 2; MICE; MODELS, BIOLOGICAL; OSTEOBLASTS; OSTEOGENESIS; OSTEOPONTIN; PERFUSION; POROSITY; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84868128051     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24566     Document Type: Article

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