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Volumn 45, Issue 6, 2012, Pages 545-556

The mechanisms of nadroparin-mediated inhibition of proliferation of two human lung cancer cell lines

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DALTEPARIN; FONDAPARINUX; MESSENGER RNA; NADROPARIN; PROTEIN P21; PROTEIN TYROSINE PHOSPHATASE; TRYPAN BLUE;

EID: 84868124456     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2012.00847.x     Document Type: Article
Times cited : (20)

References (46)
  • 2
    • 33750069402 scopus 로고    scopus 로고
    • Advances in chemotherapy of non-small cell lung cancer
    • Molina JR, Adjei AA, Jett JR (2006) Advances in chemotherapy of non-small cell lung cancer. Chest 130, 1211-1219.
    • (2006) Chest , vol.130 , pp. 1211-1219
    • Molina, J.R.1    Adjei, A.A.2    Jett, J.R.3
  • 4
    • 3042704507 scopus 로고    scopus 로고
    • Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS)
    • Kakkar AK, Levine MN, Kadziola Z, Lemoine NR, Low V, Patel HK et al. (2004) Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS). J. Clin. Oncol. 22, 1944-1948.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1944-1948
    • Kakkar, A.K.1    Levine, M.N.2    Kadziola, Z.3    Lemoine, N.R.4    Low, V.5    Patel, H.K.6
  • 5
    • 12844289104 scopus 로고    scopus 로고
    • A randomized clinical trial of combination chemotherapy with and without low-molecular-weight heparin in small cell lung cancer
    • Altinbas M, Coskun HS, Er O, Ozkan M, Eser B, Unal A et al. (2004) A randomized clinical trial of combination chemotherapy with and without low-molecular-weight heparin in small cell lung cancer. J. Thromb. Haemost. 2, 1266-1271.
    • (2004) J. Thromb. Haemost. , vol.2 , pp. 1266-1271
    • Altinbas, M.1    Coskun, H.S.2    Er, O.3    Ozkan, M.4    Eser, B.5    Unal, A.6
  • 7
    • 2342526003 scopus 로고    scopus 로고
    • CCL2 (monocyte chemoattractant protein-1) and cancer
    • Conti I, Rollins BJ (2004) CCL2 (monocyte chemoattractant protein-1) and cancer. Semin. Cancer Biol. 14, 149-154.
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 149-154
    • Conti, I.1    Rollins, B.J.2
  • 8
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
    • Borsig L, Wong R, Feramisco J, Nadeau DR, Varki NM, Varki A (2001) Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc. Natl. Acad. Sci. USA 98, 3352-3357.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3352-3357
    • Borsig, L.1    Wong, R.2    Feramisco, J.3    Nadeau, D.R.4    Varki, N.M.5    Varki, A.6
  • 9
    • 0031267194 scopus 로고    scopus 로고
    • A 5.0-kD heparin fraction systemically suppresses VEGF165-mediated angiogenesis
    • Norrby K, Ostergaard P (1997) A 5.0-kD heparin fraction systemically suppresses VEGF165-mediated angiogenesis. Int. J. Microcirc. Clin. Exp. 17, 314-321.
    • (1997) Int. J. Microcirc. Clin. Exp. , vol.17 , pp. 314-321
    • Norrby, K.1    Ostergaard, P.2
  • 10
    • 18144403761 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1)
    • Fasciano S, Patel RC, Handy I, Patel CV (2005) Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1). J. Biol. Chem. 280, 15682-15689.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15682-15689
    • Fasciano, S.1    Patel, R.C.2    Handy, I.3    Patel, C.V.4
  • 11
    • 0036739922 scopus 로고    scopus 로고
    • Contribution of double-stranded RNA-activated protein kinase toward antiproliferative actions of heparin on vascular smooth muscle cells
    • Patel RC, Handy I, Patel CV (2002) Contribution of double-stranded RNA-activated protein kinase toward antiproliferative actions of heparin on vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 22, 1439-1444.
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1439-1444
    • Patel, R.C.1    Handy, I.2    Patel, C.V.3
  • 12
    • 70350433591 scopus 로고    scopus 로고
    • Anti-cancer properties of low-molecular-weight heparin: preclinical evidence
    • Mousa SA, Petersen LJ (2009) Anti-cancer properties of low-molecular-weight heparin: preclinical evidence. Thromb. Haemost. 102, 258-267.
    • (2009) Thromb. Haemost. , vol.102 , pp. 258-267
    • Mousa, S.A.1    Petersen, L.J.2
  • 13
    • 48249094625 scopus 로고    scopus 로고
    • The effect of dalteparin, a kind of low molecular weight heparin, on lung adenocarcinoma A549 cell line in vitro
    • Chen X, Xiao W, Qu X, Zhou S (2008) The effect of dalteparin, a kind of low molecular weight heparin, on lung adenocarcinoma A549 cell line in vitro. Cancer Invest. 26, 718-724.
    • (2008) Cancer Invest. , vol.26 , pp. 718-724
    • Chen, X.1    Xiao, W.2    Qu, X.3    Zhou, S.4
  • 14
    • 1642322919 scopus 로고    scopus 로고
    • Biochemical and pharmacologic heterogeneity in low molecular weight heparins. Impact on the therapeutic profile
    • Fareed J, Hoppensteadt D, Schultz C, Ma Q, Kujawski MF, Neville B et al. (2004) Biochemical and pharmacologic heterogeneity in low molecular weight heparins. Impact on the therapeutic profile. Curr. Pharm. Des. 10, 983-999.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 983-999
    • Fareed, J.1    Hoppensteadt, D.2    Schultz, C.3    Ma, Q.4    Kujawski, M.F.5    Neville, B.6
  • 15
    • 68249161094 scopus 로고    scopus 로고
    • Differences among low-molecular-weight heparins: evidence in patients with acute coronary syndromes
    • Nicolau JC, Cohen M, Montalescot G (2009) Differences among low-molecular-weight heparins: evidence in patients with acute coronary syndromes. J. Cardiovasc. Pharmacol. 53, 440-445.
    • (2009) J. Cardiovasc. Pharmacol. , vol.53 , pp. 440-445
    • Nicolau, J.C.1    Cohen, M.2    Montalescot, G.3
  • 16
    • 0032745131 scopus 로고    scopus 로고
    • Production and chemical processing of low molecular weight heparins
    • Linhardt RJ, Gunay NS (1999) Production and chemical processing of low molecular weight heparins. Semin. Thromb. Hemost. 25(Suppl. 3), 5-16.
    • (1999) Semin. Thromb. Hemost. , vol.25 , Issue.SUPPL. 3 , pp. 5-16
    • Linhardt, R.J.1    Gunay, N.S.2
  • 18
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 19
    • 0025047803 scopus 로고
    • Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia
    • Barry MA, Behnke CA, Eastman A (1990) Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem. Pharmacol. 40, 2353-2362.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 2353-2362
    • Barry, M.A.1    Behnke, C.A.2    Eastman, A.3
  • 21
    • 0032910170 scopus 로고    scopus 로고
    • Regulating the onset of mitosis
    • Ohi R, Gould KL (1999) Regulating the onset of mitosis. Curr. Opin. Cell Biol. 11, 267-273.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 267-273
    • Ohi, R.1    Gould, K.L.2
  • 22
    • 0030561427 scopus 로고    scopus 로고
    • Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control
    • Lew DJ, Kornbluth S (1996) Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr. Opin. Cell Biol. 8, 795-804.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 795-804
    • Lew, D.J.1    Kornbluth, S.2
  • 23
    • 0043066731 scopus 로고    scopus 로고
    • Regulating mammalian checkpoints through Cdc25 inactivation
    • Donzelli M, Draetta GF (2003) Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep. 4, 671-677.
    • (2003) EMBO Rep. , vol.4 , pp. 671-677
    • Donzelli, M.1    Draetta, G.F.2
  • 24
    • 34247860861 scopus 로고    scopus 로고
    • Novel cytotoxic agents for non-small cell lung cancer
    • Edelman MJ (2006) Novel cytotoxic agents for non-small cell lung cancer. J. Thorac. Oncol. 1, 752-755.
    • (2006) J. Thorac. Oncol. , vol.1 , pp. 752-755
    • Edelman, M.J.1
  • 25
    • 33644830185 scopus 로고    scopus 로고
    • Low-molecular-weight heparins and angiogenesis
    • Norrby K (2006) Low-molecular-weight heparins and angiogenesis. APMIS 114, 79-102.
    • (2006) APMIS , vol.114 , pp. 79-102
    • Norrby, K.1
  • 26
    • 77649270151 scopus 로고    scopus 로고
    • The low-molecular-weight heparin, nadroparin, inhibits tumour angiogenesis in a rodent dorsal skinfold chamber model
    • Debergh I, Van Damme N, Pattyn P, Peeters M, Ceelen WP (2010) The low-molecular-weight heparin, nadroparin, inhibits tumour angiogenesis in a rodent dorsal skinfold chamber model. Br. J. Cancer 102, 837-843.
    • (2010) Br. J. Cancer , vol.102 , pp. 837-843
    • Debergh, I.1    Van Damme, N.2    Pattyn, P.3    Peeters, M.4    Ceelen, W.P.5
  • 27
    • 0019829625 scopus 로고
    • Cultured endothelial cells produce a heparinlike inhibitor of smooth muscle cell growth
    • Castellot JJJ, Addonizio ML, Rosenberg R, Karnovsky MJ (1981) Cultured endothelial cells produce a heparinlike inhibitor of smooth muscle cell growth. J. Cell Biol. 90, 372-379.
    • (1981) J. Cell Biol. , vol.90 , pp. 372-379
    • Castellot, J.J.J.1    Addonizio, M.L.2    Rosenberg, R.3    Karnovsky, M.J.4
  • 28
    • 0023183745 scopus 로고
    • Regulation of smooth muscle proliferation by heparin in vitro and in vivo
    • Clowes AW, Clowes MM (1987) Regulation of smooth muscle proliferation by heparin in vitro and in vivo. Int. Angiol. 6, 45-51.
    • (1987) Int. Angiol. , vol.6 , pp. 45-51
    • Clowes, A.W.1    Clowes, M.M.2
  • 30
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO (1995) Principles of CDK regulation. Nature 374, 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 31
    • 69249230769 scopus 로고    scopus 로고
    • Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
    • Satyanarayana A, Kaldis P (2009) Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 28, 2925-2939.
    • (2009) Oncogene , vol.28 , pp. 2925-2939
    • Satyanarayana, A.1    Kaldis, P.2
  • 32
    • 0024425887 scopus 로고
    • Checkpoints: controls that ensure the order of cell cycle events
    • Hartwell LH, Weinert TA (1989) Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634.
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 33
    • 0642286495 scopus 로고    scopus 로고
    • Cyclin B1 and CDK1: nuclear localization and upstream regulators
    • Porter LA, Donoghue DJ (2003) Cyclin B1 and CDK1: nuclear localization and upstream regulators. Prog. Cell Cycle Res. 5, 335-347.
    • (2003) Prog. Cell Cycle Res. , vol.5 , pp. 335-347
    • Porter, L.A.1    Donoghue, D.J.2
  • 34
    • 77951184302 scopus 로고    scopus 로고
    • Progressive activation of cyclin B1-Cdk1 coordinates entry to mitosis
    • Gavet O, Pines J (2010) Progressive activation of cyclin B1-Cdk1 coordinates entry to mitosis. Dev. Cell 18, 533-543.
    • (2010) Dev. Cell , vol.18 , pp. 533-543
    • Gavet, O.1    Pines, J.2
  • 36
    • 1342302814 scopus 로고    scopus 로고
    • A systematic review of economic analyses of low-molecular-weight heparin for the treatment of venous thromboembolism
    • Sprague S, Cook DJ, Anderson D, O'Brien BJ (2003) A systematic review of economic analyses of low-molecular-weight heparin for the treatment of venous thromboembolism. Thromb. Res. 112, 193-201.
    • (2003) Thromb. Res. , vol.112 , pp. 193-201
    • Sprague, S.1    Cook, D.J.2    Anderson, D.3    O'Brien, B.J.4
  • 37
    • 68949194321 scopus 로고    scopus 로고
    • Low-molecular-weight heparin for thromboprophylaxis
    • Camporese G, Bernardi E (2009) Low-molecular-weight heparin for thromboprophylaxis. Curr. Opin. Pulm. Med. 15, 443-454.
    • (2009) Curr. Opin. Pulm. Med. , vol.15 , pp. 443-454
    • Camporese, G.1    Bernardi, E.2
  • 38
    • 0031013428 scopus 로고    scopus 로고
    • Efficacy and safety of a low-molecular-weight heparin and standard unfractionated heparin for prophylaxis of postoperative venous thromboembolism: European multicenter trial
    • discussion 8-9.
    • Kakkar VV, Boeckl O, Boneu B, Bordenave L, Brehm OA, Brucke P et al. (1997) Efficacy and safety of a low-molecular-weight heparin and standard unfractionated heparin for prophylaxis of postoperative venous thromboembolism: European multicenter trial. World J. Surg. 21, 2-8; discussion 8-9.
    • (1997) World J. Surg. , vol.21 , pp. 2-8
    • Kakkar, V.V.1    Boeckl, O.2    Boneu, B.3    Bordenave, L.4    Brehm, O.A.5    Brucke, P.6
  • 39
    • 0024549107 scopus 로고
    • Importance of size, sulfation, and anticoagulant activity in the potentiation of acidic fibroblast growth factor by heparin
    • Sudhalter J, Folkman J, Svahn CM, Bergendal K, D'Amore PA (1989) Importance of size, sulfation, and anticoagulant activity in the potentiation of acidic fibroblast growth factor by heparin. J. Biol. Chem. 264, 6892-6897.
    • (1989) J. Biol. Chem. , vol.264 , pp. 6892-6897
    • Sudhalter, J.1    Folkman, J.2    Svahn, C.M.3    Bergendal, K.4    D'Amore, P.A.5
  • 41
    • 0028933964 scopus 로고
    • Comparison of the pharmacokinetic profiles of three low molecular mass heparins-dalteparin, enoxaparin and nadroparin-administered subcutaneously in healthy volunteers (doses for prevention of thromboembolism)
    • Collignon F, Frydman A, Caplain H, Ozoux ML, Le Roux Y, Bouthier J et al. (1995) Comparison of the pharmacokinetic profiles of three low molecular mass heparins-dalteparin, enoxaparin and nadroparin-administered subcutaneously in healthy volunteers (doses for prevention of thromboembolism). Thromb. Haemost. 73, 630-640.
    • (1995) Thromb. Haemost. , vol.73 , pp. 630-640
    • Collignon, F.1    Frydman, A.2    Caplain, H.3    Ozoux, M.L.4    Le Roux, Y.5    Bouthier, J.6
  • 43
    • 0030952743 scopus 로고    scopus 로고
    • Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide
    • Walenga JM, Jeske WP, Bara L, Samama MM, Fareed J (1997) Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide. Thromb. Res. 86, 1-36.
    • (1997) Thromb. Res. , vol.86 , pp. 1-36
    • Walenga, J.M.1    Jeske, W.P.2    Bara, L.3    Samama, M.M.4    Fareed, J.5
  • 44
    • 79960220381 scopus 로고    scopus 로고
    • Effects of antithrombotic drugs fondaparinux and tinzaparin on in vitro proliferation and osteogenic and chondrogenic differentiation of bone-derived mesenchymal stem cells
    • Papathanasopoulos A, Kouroupis D, Henshaw K, McGonagle D, Jones EA, Giannoudis PV (2011) Effects of antithrombotic drugs fondaparinux and tinzaparin on in vitro proliferation and osteogenic and chondrogenic differentiation of bone-derived mesenchymal stem cells. J. Orthop. Res. 29, 1327-1335.
    • (2011) J. Orthop. Res. , vol.29 , pp. 1327-1335
    • Papathanasopoulos, A.1    Kouroupis, D.2    Henshaw, K.3    McGonagle, D.4    Jones, E.A.5    Giannoudis, P.V.6
  • 45
    • 13944255819 scopus 로고    scopus 로고
    • Effect of low molecular weight heparin (dalteparin) and fondaparinux (Arixtra) on human osteoblasts in vitro
    • Handschin AE, Trentz OA, Hoerstrup SP, Kock HJ, Wanner GA, Trentz O (2005) Effect of low molecular weight heparin (dalteparin) and fondaparinux (Arixtra) on human osteoblasts in vitro. Br. J. Surg. 92, 177-183.
    • (2005) Br. J. Surg. , vol.92 , pp. 177-183
    • Handschin, A.E.1    Trentz, O.A.2    Hoerstrup, S.P.3    Kock, H.J.4    Wanner, G.A.5    Trentz, O.6
  • 46
    • 0242469234 scopus 로고    scopus 로고
    • Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight
    • Khorana AA, Sahni A, Altland OD, Francis CW (2003) Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight. Arterioscler. Thromb. Vasc. Biol. 23, 2110-2115.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 2110-2115
    • Khorana, A.A.1    Sahni, A.2    Altland, O.D.3    Francis, C.W.4


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