Noninvasive in vivo detection and quantification of Demodex mites by confocal laser scanning microscopy

British Journal of Dermatology

Volumn 167, Issue 5, 2012, Pages 1042-1047

  Sattler, E C ^a   Maier, T ^a   Hoffmann, V S ^b   Hegyi, J ^c   Ruzicka, T ^a   Berking, C ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY HOSPITAL BRATISLAVA   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DEMODEX; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; FEMALE; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IN VIVO STUDY; MALE; MITE INFESTATION; NON INVASIVE PROCEDURE; PRIORITY JOURNAL; ROSACEA; SKIN EXAMINATION; SKIN SURFACE;

ADULT; AGED; ANIMALS; CASE-CONTROL STUDIES; FACE; FEMALE; HUMANS; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; MITE INFESTATIONS; MITES; ROSACEA; SKIN;

EID: 84868122309     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2012.11096.x     Document Type: Article

References (47)

1. Gonzalez S, Swindells K, Rajadhyaksha M, et al. Changing paradigms in dermatology: confocal microscopy in clinical and surgical dermatology. Clin Dermatol 2003; 21: 359-69.
2. Longo C, Moscarella E, Pepe P, et al. Confocal microscopy of recurrent naevi and recurrent melanomas: a retrospective morphological study. Br J Dermatol 2011; 165: 61-8.
3. Pellacani G, Farnetani F, Gonzalez S, et al. In vivo confocal microscopy for detection and grading of dysplastic nevi: a pilot study. J Am Acad Dermatol 2012; 66: e109-21.
4. Pellacani G, Longo C, Malvehy J, et al. In vivo confocal microscopic and histopathologic correlations of dermoscopic features in 202 melanocytic lesions. Arch Dermatol 2008; 144: 1597-608.
5. Pellacani G, Scope A, Ferrari B, et al. New insights into nevogenesis: in vivo characterization and follow-up of melanocytic nevi by reflectance confocal microscopy. J Am Acad Dermatol 2009; 61: 1001-13.
6. Pellacani G, Vinceti M, Bassoli S, et al. Reflectance confocal microscopy and features of melanocytic lesions: an internet-based study of the reproducibility of terminology. Arch Dermatol 2009; 145: 1137-43.
7. Rajadhyaksha M,. Confocal microscopy of skin cancers: translational advances toward clinical utility. Conf Proc IEEE Eng Med Biol Soc 2009; 2009: 3231-3.
8. Segura S, Pellacani G, Puig S, et al. In vivo microscopic features of nodular melanomas: dermoscopy, confocal microscopy, and histopathologic correlates. Arch Dermatol 2008; 144: 1311-20.
9. Segura S, Puig S, Carrera C, et al. Development of a two-step method for the diagnosis of melanoma by reflectance confocal microscopy. J Am Acad Dermatol 2009; 61: 216-29.
10. Maier T, Sattler EC, Braun-Falco M, et al., Reflectance confocal microscopy in the diagnosis of partially and completely amelanotic melanoma: report on seven cases. J Eur Acad Dermatol Venereol 2012 Feb 10; Epub ahead of print. doi:10.1111/j.1468-3083.2012.04465.x.
11. Gonzalez S,. Confocal reflectance microscopy in dermatology: promise and reality of non-invasive diagnosis and monitoring. Actas Dermosifiliogr 2009; 100 (Suppl. 2): 59-69.
12. Segura S, Puig S, Carrera C, et al. Non-invasive management of non-melanoma skin cancer in patients with cancer predisposition genodermatosis: a role for confocal microscopy and photodynamic therapy. J Eur Acad Dermatol Venereol 2011; 25: 819-27.
13. Ulrich M, Gonzalez S, Lange-Asschenfeldt B, et al. Non-invasive diagnosis and monitoring of actinic cheilitis with reflectance confocal microscopy. J Eur Acad Dermatol Venereol 2011; 25: 276-84.
14. Ulrich M, Kanitakis J, Gonzalez S, et al. Evaluation of Bowen disease by in vivo reflectance confocal microscopy. Br J Dermatol 2012; 166: 451-3.
15. Ulrich M, Lange-Asschenfeldt S, Gonzalez S,. Clinical applicability of in vivo reflectance confocal microscopy in dermatology. G Ital Dermatol Venereol 2012; 147: 171-8.
16. Ulrich M, Maltusch A, Rius-Diaz F, et al. Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses. Dermatol Surg 2008; 34: 610-19.
17. Ulrich M, Maltusch A, Rowert-Huber J, et al. Actinic keratoses: non-invasive diagnosis for field cancerisation. Br J Dermatol 2007; 156 (Suppl. 3): 13-17.
18. Ulrich M, Roewert-Huber J, Gonzalez S, et al. Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology. J Cutan Pathol 2011; 38: 190-5.
19. Agero AL, Busam KJ, Benvenuto-Andrade C, et al. Reflectance confocal microscopy of pigmented basal cell carcinoma. J Am Acad Dermatol 2006; 54: 638-43.
20. Agero AL, Gill M, Ardigo M, et al. In vivo reflectance confocal microscopy of mycosis fungoides: a preliminary study. J Am Acad Dermatol 2007; 57: 435-41.
21. Astner S, Gonzalez E, Cheung A, et al. Pilot study on the sensitivity and specificity of in vivo reflectance confocal microscopy in the diagnosis of allergic contact dermatitis. J Am Acad Dermatol 2005; 53: 986-92.
22. Astner S, Gonzalez E, Cheung AC, et al. Non-invasive evaluation of the kinetics of allergic and irritant contact dermatitis. J Invest Dermatol 2005; 124: 351-9.
23. Astner S, Gonzalez S, Gonzalez E,. Noninvasive evaluation of allergic and irritant contact dermatitis by in vivo reflectance confocal microscopy. Dermatitis 2006; 17: 182-91.
24. Ardigo M, Cota C, Berardesca E, et al. Concordance between in vivo reflectance confocal microscopy and histology in the evaluation of plaque psoriasis. J Eur Acad Dermatol Venereol 2009; 23: 660-7.
25. Ardigo M, Maliszewski I, Cota C, et al. Preliminary evaluation of in vivo reflectance confocal microscopy features of discoid lupus erythematosus. Br J Dermatol 2007; 156: 1196-203.
26. Gonzalez S, Rajadhyaksha M, Rubinstein G, et al. Characterization of psoriasis in vivo by reflectance confocal microscopy. J Med 1999; 30: 337-56.
27. Hegyi J, Hegyi V, Messer G, et al. Confocal laser-scanning capillaroscopy: a novel approach to the analysis of skin capillaries in vivo. Skin Res Technol 2009; 15: 476-81.
28. Rothmund G, Sattler EC, Kaestle R, et al., Confocal laser scanning microscopy as a new valuable tool in the diagnosis of onychomycosis-comparison of six diagnostic methods. Mycoses 2012 Apr 23; Epub ahead of print. doi:10.1111/j.1439-0507.2012.02198.x.
29. Sattler E, Kaestle R, Rothmund G, et al. Confocal laser scanning microscopy, optical coherence tomography and transonychial water loss for in vivo investigation of nails. Br J Dermatol 2012; 166: 740-6.
30. Slutsky JB, Rabinovitz H, Grichnik JM, Marghoob AA,. Reflectance confocal microscopic features of dermatophytes, scabies, and demodex. Arch Dermatol 2011; 147: 1008.
31. Longo C, Bassoli S, Monari P, et al. Reflectance-mode confocal microscopy for the in vivo detection of Sarcoptes scabiei. Arch Dermatol 2005; 141: 1336.
32. Longo C, Pellacani G, Ricci C, et al. In vivo detection of Demodex folliculorum by means of confocal microscopy. Br J Dermatol 2012; 166: 690-2.
33. Kligman AM, Christensen MS,. Demodex folliculorum: requirements for understanding its role in human skin disease. J Invest Dermatol 2011; 131: 8-10.
34. Marks R, Dawber RP,. Skin surface biopsy: an improved technique for the examination of the horny layer. Br J Dermatol 1971; 84: 117-23.
35. Mills OH Jr, Kligman AM,. The follicular biopsy. Dermatologica 1983; 167: 57-63.
36. Forton F, Song M,. Limitations of standardized skin surface biopsy in measurement of the density of Demodex folliculorum. A case report. Br J Dermatol 1998; 139: 697-700.
37. Askin U, Seckin D,. Comparison of the two techniques for measurement of the density of Demodex folliculorum: standardized skin surface biopsy and direct microscopic examination. Br J Dermatol 2010; 162: 1124-6.
38. Gonzalez S, Gill M, Halpern AC, (eds). Reflectance Confocal Microscopy of Cutaneous Tumors. London: Informa Healthcare, 2008.
39. Baima B, Sticherling M,. Demodicidosis revisited. Acta Derm Venereol (Stockh) 2002; 82: 3-6.
40. Bonnar E, Eustace P, Powell FC,. The Demodex mite population in rosacea. J Am Acad Dermatol 1993; 28: 443-8.
41. Cribier B,. [Physiopathology of rosacea. Redness, telangiectasia, and rosacea]. Ann Dermatol Venereol 2011; 138 (Suppl. 2): S129-37.
42. Rufli T,. [Rosacea and Demodex]. J Dtsch Dermatol Ges 2005; 3: 585-6.
43. Rufli T, Mumcuoglu Y,. The hair follicle mites Demodex folliculorum and Demodex brevis: biology and medical importance. A review. Dermatologica 1981; 162: 1-11.
44. Rufli T, Mumcuoglu Y, Cajacob A, et al. [Demodex folliculorum: aetiopathogenesis and therapy of rosacea and perioral dermatitis]. Dermatologica 1981; 162: 12-26.
45. Georgala S, Katoulis AC, Kylafis GD, et al. Increased density of Demodex folliculorum and evidence of delayed hypersensitivity reaction in subjects with papulopustular rosacea. J Eur Acad Dermatol Venereol 2001; 15: 441-4.
46. Burns DA,. Follicle mites and their role in disease. Clin Exp Dermatol 1992; 17: 152-5.
47. Borgo SN, Sattler EC, Hogardt M, et al. PCR analysis for Wolbachia in human and canine Demodex mites. Arch Dermatol Res 2009; 301: 747-52.