메뉴 건너뛰기




Volumn 120, Issue 16, 2012, Pages 3318-3325

Defective regulatory B-cell compartment in patients with immune thrombocytopenia

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD24 ANTIGEN; CD38 ANTIGEN; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

EID: 84868100092     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-05-432575     Document Type: Article
Times cited : (163)

References (43)
  • 2
    • 0034698829 scopus 로고    scopus 로고
    • B lymphocytes regulate dendritic cell (DC) function in vivo: Increased interleukin 12 production by DCs from B cell-deficient mice results in T helper cell type 1 deviation
    • DOI 10.1084/jem.192.4.475
    • Moulin V, Andris F, Thielemans K, Maliszewski C, Urbain J, Moser M. B lymphocytes regulate dendritic cell (DC) function in vivo: increased interleukin 12 production by DCs from B cell-deficient mice results in T helper cell type 1 deviation. J Exp Med. 2000;192(4):475-482. (Pubitemid 30666248)
    • (2000) Journal of Experimental Medicine , vol.192 , Issue.4 , pp. 475-482
    • Moulin, V.1    Andris, F.2    Thielemans, K.3    Maliszewski, C.4    Urbain, J.5    Moser, M.6
  • 3
    • 74649083783 scopus 로고    scopus 로고
    • CD19 (+) CD24 (hi) CD38 (hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
    • Blair PA, Norena LY, Flores-Borja F, et al. CD19 (+) CD24 (hi) CD38 (hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity. 2010;32(1):129-140.
    • (2010) Immunity , vol.32 , Issue.1 , pp. 129-140
    • Blair, P.A.1    Norena, L.Y.2    Flores-Borja, F.3
  • 4
    • 77957164949 scopus 로고    scopus 로고
    • IL-10 produced by activated human B cells regulates CD4 (+) T-cell activation in vitro
    • Bouaziz JD, Calbo S, Maho-Vaillant M, et al. IL-10 produced by activated human B cells regulates CD4 (+) T-cell activation in vitro. Eur J Immunol. 2010;40(10):2686-2691.
    • (2010) Eur J Immunol. , vol.40 , Issue.10 , pp. 2686-2691
    • Bouaziz, J.D.1    Calbo, S.2    Maho-Vaillant, M.3
  • 5
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
    • Iwata Y, Matsushita T, Horikawa M, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood. 2011;117(2):530-541.
    • (2011) Blood , vol.117 , Issue.2 , pp. 530-541
    • Iwata, Y.1    Matsushita, T.2    Horikawa, M.3
  • 6
    • 77953178765 scopus 로고    scopus 로고
    • Identification of a B cell signature associated with renal transplant tolerance in humans
    • Newell KA, Asare A, Kirk AD, et al. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest. 2010;120(6):1836-1847.
    • (2010) J Clin Invest. , vol.120 , Issue.6 , pp. 1836-1847
    • Newell, K.A.1    Asare, A.2    Kirk, A.D.3
  • 7
    • 84859385739 scopus 로고    scopus 로고
    • Immune regulatory function of B cells
    • Mauri C, Bosma A. Immune regulatory function of B cells. Ann Rev Immunol. 2012;30:221-41.
    • (2012) Ann Rev Immunol. , vol.30 , pp. 221-241
    • Mauri, C.1    Bosma, A.2
  • 8
    • 79956224216 scopus 로고    scopus 로고
    • Mice lacking endogenous IL-10-producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells
    • Carter NA, Vasconcellos R, Rosser EC, et al. Mice lacking endogenous IL-10-producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells. J Immunol. 2011;186(10):5569-5579.
    • (2011) J Immunol. , vol.186 , Issue.10 , pp. 5569-5579
    • Carter, N.A.1    Vasconcellos, R.2    Rosser, E.C.3
  • 9
    • 77951667958 scopus 로고    scopus 로고
    • Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model
    • Amu S, Saunders SP, Kronenberg M, Mangan NE, Atzberger A, Fallon PG. Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model. J Allergy Clin Immunol. 2010;125(5):1114-1124.
    • (2010) J Allergy Clin Immunol. , vol.125 , Issue.5 , pp. 1114-1124
    • Amu, S.1    Saunders, S.P.2    Kronenberg, M.3    Mangan, N.E.4    Atzberger, A.5    Fallon, P.G.6
  • 10
    • 61449111086 scopus 로고    scopus 로고
    • Chronic idiopathic thrombocytopenic purpura: Mechanisms of pathogenesis
    • Gernsheimer T. Chronic idiopathic thrombocytopenic purpura: mechanisms of pathogenesis. Oncologist. 2009;14(1):12-21.
    • (2009) Oncologist , vol.14 , Issue.1 , pp. 12-21
    • Gernsheimer, T.1
  • 11
    • 73949129334 scopus 로고    scopus 로고
    • The effects of BAFF and BAFF-R-Fc fusion protein in immune thrombocytopenia
    • Zhu XJ, Shi Y, Peng J, et al. The effects of BAFF and BAFF-R-Fc fusion protein in immune thrombocytopenia. Blood. 2009;114(26):5362-5367.
    • (2009) Blood , vol.114 , Issue.26 , pp. 5362-5367
    • Zhu, X.J.1    Shi, Y.2    Peng, J.3
  • 13
    • 0036493366 scopus 로고    scopus 로고
    • -) in subgroups of patients with common variable immunodeficiency: A new approach to classify a heterogeneous disease
    • DOI 10.1182/blood.V99.5.1544
    • Warnatz K, Denz A, Drager R, et al. Severe deficiency of switched memory B cells (CD27 (+) IgM (-) IgD (-)) in subgroups of patients with common variable immunodeficiency: a new approach to classify a heterogeneous disease. Blood. 2002;99(5):1544-1551. (Pubitemid 34533024)
    • (2002) Blood , vol.99 , Issue.5 , pp. 1544-1551
    • Warnatz, K.1    Denz, A.2    Drager, R.3    Braun, M.4    Groth, C.5    Wolff-Vorbeck, G.6    Eibel, H.7    Schlesier, M.8    Peter, H.H.9
  • 14
    • 79951481124 scopus 로고    scopus 로고
    • High-dose dexamethasone shifts the balance of stimulatory and inhibitory Fcgamma receptors on monocytes in patients with primary immune thrombocytopenia
    • Liu XG, Ma SH, Sun JZ, et al. High-dose dexamethasone shifts the balance of stimulatory and inhibitory Fcgamma receptors on monocytes in patients with primary immune thrombocytopenia. Blood. 2011;117(6):2061-2069.
    • (2011) Blood , vol.117 , Issue.6 , pp. 2061-2069
    • Liu, X.G.1    Ma, S.H.2    Sun, J.Z.3
  • 15
    • 0025876206 scopus 로고
    • Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia
    • Semple JW, Freedman J. Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia. Blood. 1991;78(10):2619-2625.
    • (1991) Blood , vol.78 , Issue.10 , pp. 2619-2625
    • Semple, J.W.1    Freedman, J.2
  • 16
    • 0029964421 scopus 로고    scopus 로고
    • Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: Relationship to platelet phenotype and antiplatelet T-cell reactivity
    • Semple JW, Milev Y, Cosgrave D, et al. Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity. Blood. 1996;87(10):4245-4254. (Pubitemid 26152268)
    • (1996) Blood , vol.87 , Issue.10 , pp. 4245-4254
    • Semple, J.W.1    Milev, Y.2    Cosgrave, D.3    Mody, M.4    Hornstein, A.5    Blanchette, V.6    Freedman, J.7
  • 18
    • 0032190549 scopus 로고    scopus 로고
    • Autoreactive T cells to platelet GPIIb-IIIa in immune thrombocytopenic purpura: Role in production of anti-platelet autoantibody
    • Kuwana M, Kaburaki J, Ikeda Y. Autoreactive T cells to platelet GPIIb-IIIa in immune thrombocytopenic purpura. Role in production of antiplatelet autoantibody. J Clin Invest. 1998;102(7):1393-1402. (Pubitemid 28467568)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.7 , pp. 1393-1402
    • Kuwana, M.1    Kaburaki, J.2    Ikeda, Y.3
  • 19
    • 0035412364 scopus 로고    scopus 로고
    • Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T cells in patients with immune thrombocytopenic purpura
    • Kuwana M, Kaburaki J, Kitasato H, et al. Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T cells in patients with immune thrombocytopenic purpura. Blood. 2001;98(1):130-139.
    • (2001) Blood , vol.98 , Issue.1 , pp. 130-139
    • Kuwana, M.1    Kaburaki, J.2    Kitasato, H.3
  • 22
    • 34548595302 scopus 로고    scopus 로고
    • + regulatory T cells in adult patients with chronic ITP before and after treatment with high-dose dexamethasome
    • DOI 10.1111/j.1600-0609.2007.00917.x
    • Ling Y, Cao X, Yu Z, Ruan C. Circulating dendritic cells subsets and CD4+Foxp3+ regulatory T cells in adult patients with chronic ITP before and after treatment with high-dose dexamethasome. Eur J Haematol. 2007;79(4):310-316. (Pubitemid 47390130)
    • (2007) European Journal of Haematology , vol.79 , Issue.4 , pp. 310-316
    • Ling, Y.1    Cao, X.2    Yu, Z.3    Ruan, C.4
  • 23
    • 51649091745 scopus 로고    scopus 로고
    • Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B celldepleting therapy with rituximab
    • Stasi R, Cooper N, Del Poeta G, et al. Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B celldepleting therapy with rituximab. Blood. 2008;112(4):1147-1150.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1147-1150
    • Stasi, R.1    Cooper, N.2    Del Poeta, G.3
  • 24
    • 51649127854 scopus 로고    scopus 로고
    • Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura
    • Yu J, Heck S, Patel V, et al. Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura. Blood. 2008;112(4):1325-1328.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1325-1328
    • Yu, J.1    Heck, S.2    Patel, V.3
  • 25
    • 80054834604 scopus 로고    scopus 로고
    • Immunologic effects of rituximab on the human spleen in immune thrombocytopenia
    • Audia S, Samson M, Guy J, et al. Immunologic effects of rituximab on the human spleen in immune thrombocytopenia. Blood. 2011;118(16):4394-4400.
    • (2011) Blood , vol.118 , Issue.16 , pp. 4394-4400
    • Audia, S.1    Samson, M.2    Guy, J.3
  • 28
    • 63849111465 scopus 로고    scopus 로고
    • Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP
    • Bussel JB, Kuter DJ, Pullarkat V, et al. Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP. Blood. 2009;113(10):2161-2171.
    • (2009) Blood , vol.113 , Issue.10 , pp. 2161-2171
    • Bussel, J.B.1    Kuter, D.J.2    Pullarkat, V.3
  • 29
    • 73349086852 scopus 로고    scopus 로고
    • Update on eltrombopag for ITP
    • Bussel JB. Update on eltrombopag for ITP. Oncology. 2009;23(13):1177- 1178.
    • (2009) Oncology. , vol.23 , Issue.13 , pp. 1177-1178
    • Bussel, J.B.1
  • 31
    • 78149479585 scopus 로고    scopus 로고
    • Romiplostim or standard of care in patients with immune thrombocytopenia
    • Kuter DJ, Rummel M, Boccia R, et al. Romiplostim or standard of care in patients with immune thrombocytopenia. N Engl J Med. 2010;363(20):1889-1899.
    • (2010) N Engl J Med. , vol.363 , Issue.20 , pp. 1889-1899
    • Kuter, D.J.1    Rummel, M.2    Boccia, R.3
  • 32
    • 78649486228 scopus 로고    scopus 로고
    • Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents
    • Bao W, Bussel JB, Heck S, et al. Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents. Blood. 2010;116(22):4639-4645.
    • (2010) Blood , vol.116 , Issue.22 , pp. 4639-4645
    • Bao, W.1    Bussel, J.B.2    Heck, S.3
  • 33
    • 58049101778 scopus 로고    scopus 로고
    • Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpura
    • Martinez-Gamboa L, Mei H, Loddenkemper C, et al. Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpura. Clin Immunol. 2009;1309(2):199-212.
    • (2009) Clin Immunol. , vol.1309 , Issue.2 , pp. 199-212
    • Martinez-Gamboa, L.1    Mei, H.2    Loddenkemper, C.3
  • 34
    • 51549117128 scopus 로고    scopus 로고
    • Memory B cells and pneumococcal antibody after splenectomy
    • Wasserstrom H, Bussel J, Lim LC, Cunningham-Rundles C. Memory B cells and pneumococcal antibody after splenectomy. J Immunol. 2008;181(5):3684-3689.
    • (2008) J Immunol. , vol.181 , Issue.5 , pp. 3684-3689
    • Wasserstrom, H.1    Bussel, J.2    Lim, L.C.3    Cunningham-Rundles, C.4
  • 36
    • 0037109144 scopus 로고    scopus 로고
    • 3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells
    • DOI 10.1161/01.CIR.0000033597.45947.0F
    • May AE, Kalsch T, Massberg S, et al. Engagement of glycoprotein IIb/IIIa (alpha (IIb) beta3) on platelets upregulates CD40L and triggers CD40Ldependent matrix degradation by endothelial cells. Circulation. 2002;106(16):2111-2117. (Pubitemid 35192818)
    • (2002) Circulation , vol.106 , Issue.16 , pp. 2111-2117
    • May, A.E.1    Kalsch, T.2    Massberg, S.3    Herouy, Y.4    Schmidt, R.5    Gawaz, M.6
  • 37
    • 0035478494 scopus 로고    scopus 로고
    • Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome
    • Bohnhorst JO, Bjorgan MB, Thoen JE, Natvig JB, Thompson KM. Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome. J Immunol. 2001;167(7):3610-3618. (Pubitemid 32916053)
    • (2001) Journal of Immunology , vol.167 , Issue.7 , pp. 3610-3618
    • Bohnhorst, J.O.1    Bjorgan, M.B.2    Thoen, J.E.3    Natvig, J.B.4    Thompson, K.M.5
  • 38
    • 0035881627 scopus 로고    scopus 로고
    • Increased frequency of pre-germinal center b cells and plasma cell precursors in the blood of children with systemic lupus erythematosus
    • Arce E, Jackson DG, Gill MA, Bennett LB, Banchereau J, Pascual V. Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J Immunol. 2001;167(4):2361-2369. (Pubitemid 32747551)
    • (2001) Journal of Immunology , vol.167 , Issue.4 , pp. 2361-2369
    • Arce, E.1    Jackson, D.G.2    Gill, M.A.3    Bennett, L.B.4    Banchereau, J.5    Pascual, V.6
  • 39
    • 0031213740 scopus 로고    scopus 로고
    • Regulation of B-cell commitment to plasma cells or to memory B cells
    • DOI 10.1006/smim.1997.0080
    • Liu YJ, Banchereau J. Regulation of B-cell commitment to plasma cells or to memory B cells. Semin Immunol. 1997;99(4):235-240. (Pubitemid 27331992)
    • (1997) Seminars in Immunology , vol.9 , Issue.4 , pp. 235-240
    • Liu, Y.-J.1    Banchereau, J.2
  • 40
    • 0042326418 scopus 로고    scopus 로고
    • T cell receptor VB repertoire diversity in patients with immune thrombocytopenia following splenectomy
    • DOI 10.1046/j.1365-2249.2003.02239.x
    • Fogarty PF, Rick ME, Zeng W, Risitano AM, Dunbar CE, Bussel JB. T cell receptor VB repertoire diversity in patients with immune thrombocytopenia following splenectomy. Clin Exp Immunol. 2003;133(3):461-466. (Pubitemid 37046973)
    • (2003) Clinical and Experimental Immunology , vol.133 , Issue.3 , pp. 461-466
    • Fogarty, P.F.1    Rick, M.E.2    Zeng, W.3    Risitano, A.M.4    Dunbar, C.E.5    Bussel, J.B.6
  • 41
    • 77953182426 scopus 로고    scopus 로고
    • B cells as therapeutic targets in SLE
    • Sanz I, Lee FE. B cells as therapeutic targets in SLE. Nat Rev Rheumatol. 2010;6(6):326-337.
    • (2010) Nat Rev Rheumatol. , vol.6 , Issue.6 , pp. 326-337
    • Sanz, I.1    Lee, F.E.2
  • 42
    • 35548960551 scopus 로고    scopus 로고
    • Response to B-cell-depleting therapy with rituximab reverts the abnormalities of T-cell subsets in patients with idiopathic thrombocytopenic purpura
    • DOI 10.1182/blood-2007-02-068999
    • Stasi R, Del Poeta G, Stipa E, et al. Response to B-cell depleting therapy with rituximab reverts the abnormalities of T-cell subsets in patients with idiopathic thrombocytopenic purpura. Blood. 2007;110(8):2924-2930. (Pubitemid 350006946)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2924-2930
    • Stasi, R.1    Del Poeta, G.2    Stipa, E.3    Evangelista, M.L.4    Trawinska, M.M.5    Cooper, N.6    Amadori, S.7
  • 43
    • 84861724649 scopus 로고    scopus 로고
    • Human CD19 (+) CD25 (high) B regulatory cells suppress proliferation of CD4 (+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells
    • Kessel A, Haj T, Peri R, et al. Human CD19 (+) CD25 (high) B regulatory cells suppress proliferation of CD4 (+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells. Autoimmun Rev. 2012;11(9):670-677.
    • (2012) Autoimmun Rev. , vol.11 , Issue.9 , pp. 670-677
    • Kessel, A.1    Haj, T.2    Peri, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.