Synthesis and Structural Characterisation of Selective Non-Carbohydrate-Based Inhibitors of Bacterial Sialidases

ChemBioChem

Volumn 13, Issue 16, 2012, Pages 2374-2383

  Brear, Paul ^a   Telford, Judith ^a   Taylor, Garry L ^a   Westwood, Nicholas J ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

B factors; Beta amino sulfonic acids; Non carbohydrate inhibitors; Protein ligand complexes; Sialidases

Indexed keywords

2 (BENZYLAMMONIO)ETHANESULFONATE; 2 (CYCLOHEXYLAMMONIO)ETHANESULFONATE; 2 (TERT BUTYLAMMONIO)ETHANESULFONATE; 2 [(2 HYDROXYETHYL)AMMONIO]ETHANESULFONATE; 2 [(2 METHOXYBENZYL)AMMONIO]ETHANESULFONATE; 2 [(2 METHYLBENZYL)AMMONIO]ETHANESULFONATE; 2 [(2 PHENYLETHYL)AMMONIO]ETHANESULFONATE; 2 [(3 BROMOBENZYL)AMMONIO]ETHANESULFONATE; 2 [(3 CHLORO 4 FLUORO)AMMONIO]ETHANESULFONATE; 2 [(3 CHLOROBENZYL)AMMONIO]ETHANESULFONATE; 2 [(3 FLUOROBENZYL)AMMONIO]ETHANESULFONATE; 2 [(3 HYDROXYBENZYL)AMMONIO]ETHANESULFONATE; 2 [(3 METHOXYBENZYL)AMMONIO]ETHANESULFONATE; 2 [(3 METHYLBENZYL)AMMONIO]ETHANESULFONATE; 2 [(3,4 DICHLOROBENZYL)AMMONIO]ETHANESULFONATE; 2 [(4 CHLOROBENZYL)AMMONIO]ETHANESULFONATE; 2 [(4 FLUORO 3 METHYLBENZYL)AMMONIO]ETHANESULFONATE; 2 [(4 METHOXYBENZYL)AMMONIO]ETHANESULFONATE; 2 [(4 METHYLBENZYL)AMMONIO]ETHANESULFONATE; 2 [(CYCLOHEXYLMETHYL)AMMONIO]ETHANESULFONATE; 2 [(FURAN 2 YLMETHYL)AMMONIO]ETHANESULFONATE; 3 (CYCLOHEXYL AMMONIO)PROPANE 1 SULFONATE; 3 AMMONIOPROPANE 1 SULFONATE; [(DIPHENYLMETHYL)AMMONIO]ETHANESULFONATE; CYCLOHEXYLAMINE; ISOPROP 2 YL ETHENESULFONATE; NANB ENZYME; SIALIDASE; SIALIDASE INHIBITOR; TAURINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HYMECROMONE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEURAMINIDASE; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

EID: 84868097065     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201200433     Document Type: Article

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