Synthesis, SAR and biological evaluation of natural and non-natural hydroxylated and prenylated xanthones as antitumor agents

Medicinal Chemistry

Volumn 8, Issue 6, 2012, Pages 1012-1025

  Zhang, Xiaojin ^a   Li, Xiang ^a   Ye, Suofu ^a   Zhang, Yu ^a   Tao, Lei ^a   Gao, Yuan ^a   Gong, Dandan ^a   Xi, Meiyang ^a   Meng, Huyan ^a   Zhang, Mingqian ^a   Gao, Wenlei ^a   Xu, Xiaoli ^a   Guo, Qinglong ^a   You, Qidong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Mangostin; Anti Proliferative; Antitumor; Apoptosis; Cell Cycle Arrest; SAR; Xanthone

Indexed keywords

1 HYDROXY 9H XANTHEN 9 ONE; 1,3 DIHYDROXY 9H XANTHEN 9 ONE; 1,3,5 TRIHYDROXY 9H XANTHEN 9 ONE; 1,3,5,6 TETRAHYDROXY 9H XANTHEN 9 ONE; 1,3,5,6 TETRAHYDROXYXANTHONE; 1,3,6 TRIHYDROXY 9H XANTHEN 9 ONE; 1,3,8 TRIHYDROXY 2 PRENYLXANTHONE; 1,3,8 TRIHYDROXY 9H XANTHEN 9 ONE; 1,5,6 TRIHYDROXY 9H XANTHEN 9 ONE; 1,6 DIHYDROXY 9H XANTHEN 9 ONE; 1,8 DIHYDROXY 9H XANTHEN 9 ONE; 2,3,2',4' TETRAHYDROXYBENZOPHONE; 2,4,2',4' TETRAHYDROXYBENZOPHON; 2,4,2',5' TETRAHYDROXYBENZOPHONE; 2,5,6 TRIHYDROXY 9H XANTHEN 9 ONE; 2,6 DIHYDROXY 9H XANTHEN 9 ONE; 3,4 DIHYDROXY 9H XANTHEN 9 ONE; 3,4,6 TRIHYDROXY 9H XANTHEN 9 ONE; 3,5 DIHYDROXY 9H XANTHEN 9 ONE; 3,6 DIHYDROXY 9H XANTHEN 9 ONE; 8 DEOXYGARTANIN; ALPHA MANGOSTIN; ANTINEOPLASTIC AGENT; BUXANTHONE; CARBONYL DERIVATIVE; GENTISEIN; PRENYLAMINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHONE 4 ACETIC ACID; XANTHONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL STRAIN HEPG2; COLON CARCINOMA; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROXYLATION; LUNG CARCINOMA; PRENYLATION; PRIORITY JOURNAL; STOMACH CARCINOMA; STRUCTURE ACTIVITY RELATION;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL AGENTS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY TECHNIQUES, SYNTHETIC; HUMANS; HYDROXYLATION; PRENYLATION; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHONES;

EID: 84868034789     PISSN: 15734064     EISSN: 18756638     Source Type: Journal    
DOI: 10.2174/1573406411208061012     Document Type: Article

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