3D GRASE arterial spin labelling reveals an inverse correlation of cortical perfusion with the white matter lesion volume in MS

Multiple Sclerosis Journal

Volumn 18, Issue 11, 2012, Pages 1570-1576

  Amann, Michael ^a   Achtnichts, Lutz ^a   Hirsch, Jochen G ^a,b   Naegelin, Yvonne ^a   Gregori, Johannes ^c   Weier, Katrin ^a   Thöni, Alain ^a,d   Mueller Lenke, Nicole ^a,d   Radue, Ernst Wilhelm ^a,d   Günther, Matthias ^b,c,e   Kappos, Ludwig ^a   Gass, Achim ^a,f  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF BREMEN   (Germany)

^c FRAUNHOFER MEVIS   (Germany)

^d Medical Image Analysis Centre   (Switzerland)

^e MEDIRI GMBH   (Germany)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

arterial spin labelling; cerebral blood flow; cortical perfusion; lesion load; multiple sclerosis; pulsed arterial spin labelling

Indexed keywords

SPIN LABELING;

ADULT; AGED; ATROPHY; BLOOD FLOW; BLOOD FLOW VELOCITY; BRAIN CIRCULATION; BRAIN CORTEX; DISABILITY; FEMALE; HUMAN; LEUKOENCEPHALOPATHIES; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PROCEDURES; SCINTIGRAPHY; SPIN LABELING; STATISTICAL MODEL; VASCULARIZATION; YOUNG ADULT;

ADULT; AGED; ATROPHY; BLOOD FLOW VELOCITY; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; DISABILITY EVALUATION; FEMALE; HUMANS; LEUKOENCEPHALOPATHIES; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; MULTIVARIATE ANALYSIS; PERFUSION IMAGING; PREDICTIVE VALUE OF TESTS; REGIONAL BLOOD FLOW; SPIN LABELS; YOUNG ADULT;

EID: 84868013749     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512441984     Document Type: Article

References (35)

1. Compston A, Coles A. Multiple sclerosis. Lancet. 2002 ; 359: 1221-1231 (Pubitemid 34304266)
2. Lassmann H, Suchanek G, Ozawa K. Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis. Ann Neurol. 1994 ; 36: S42 - S46
3. Losseff NA, Wang L, Lai HM, et al. Progressive cerebral atrophy in multiple sclerosis. A serial MRI study. Brain. 1996 ; 119: 2009-2019
4. De Stefano N, Iannucci G, Sormani MP, et al. MR correlates of cerebral atrophy in patients with multiple sclerosis. J Neurol. 2002 ; 249: 1072-1077 (Pubitemid 35002232)
5. Miller DH, Barkhof F, Frank JA, et al. Measurement of atrophy in multiple sclerosis: Pathological basis, methodological aspects and clinical relevance. Brain. 2002 ; 125: 1676-1695
6. Arnold DL, Matthews PM, Francis G, et al. Proton magnetic resonance spectroscopy of human brain in vivo in the evaluation of multiple sclerosis: assessment of the load of disease. Magn Reson Med. 1990 ; 14: 154-159 (Pubitemid 20243873)
7. Matthews PM, Pioro E, Narayanan S, et al. Assessment of lesion pathology in multiple sclerosis using quantitative MRI morphometry and magnetic resonance spectroscopy. Brain. 1996 ; 119: 715-722 (Pubitemid 26237171)
8. Davies SE, Newcombe J, Williams SR, et al. High resolution proton NMR spectroscopy of multiple sclerosis lesions. J Neurochem. 1995 ; 64: 742-748
9. Trapp BD, Ransohoff R, Rudick R. Axonal pathology in multiple sclerosis: Relationship to neurologic disability. Curr Opin Neurol. 1999 ; 12: 295-302 (Pubitemid 29378163)
10. Brooks DJ, Leenders KL, Head G, et al. Studies on regional cerebral oxygen utilisation and cognitive function in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1984 ; 47: 1182-1191 (Pubitemid 15204531)
11. Pozzilli C, Passafiume D, Bernardi S, et al. SPECT, MRI and cognitive functions in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1991 ; 54: 110-115
12. Lycke J, Wikkelsö C, Bergh AC, et al. Regional cerebral blood flow in multiple sclerosis measured by single photon emission tomography with technetium-99m hexamethylpropyleneamine oxime. Eur Neurol. 1993 ; 33: 163-167 (Pubitemid 23100544)
13. Roelcke U, Kappos L, Lechner-Scott J, et al. Reduced glucose metabolism in the frontal cortex and basal ganglia of multiple sclerosis patients with fatigue: A 18F-fluorodeoxyglucose positron emission tomography study. Neurology. 1997 ; 48: 1566-1571
14. Kim SG. Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: Application to functional mapping. Magn Reson Med. 1995 ; 34: 293-301
15. Wong EC, Buxton RB, Frank LR. Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II). Magn Reson Med. 1998 ; 39: 702-708 (Pubitemid 28189141)
16. Günther M, Oshio K, Feinberg DA. Single-shot 3D imaging techniques improve arterial spin labeling perfusion measurements. Magn Reson Med. 2005 ; 54: 491-498 (Pubitemid 41033572)
17. Weier K, Naegelin Y, Thoeni A, et al. Non-communicating syringomyelia: A feature of spinal cord involvement in multiple sclerosis. Brain. 2008 ; 131: 1776-1782 (Pubitemid 351957447)
18. Bendfeldt K, Kuster P, Traud S, et al. Association of regional gray matter volume loss and progression of white matter lesions in multiple sclerosis-a longitudinal voxel-based morphometry study. NeuroImage. 2009 ; 45: 60-67
19. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology. 1983 ; 33: 1444-1452 (Pubitemid 14237132)
20. Oshio K, Feinberg DA. GRASE (gradient- and spin-echo) imaging: A novel fast MRI technique. Magn Reson Med. 1991 ; 20: 344-349
21. Petersen ET, Zimine I, Ho YCL, et al. Non-invasive measurement of perfusion: A critical review of arterial spin labelling techniques. Br J Radiol. 2006 ; 79: 688-701 (Pubitemid 44283159)
22. Cox RW. AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res. 1996 ; 29: 162-173 (Pubitemid 26266657)
23. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp. 2002 ; 17: 143-155 (Pubitemid 35253488)
24. Zhang Y, Brady M, Smith S. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging. 2001 ; 20: 45-57 (Pubitemid 32293419)
25. Smith SM, Jenkinson M, Woolrich MW, et al. Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage. 2004 ; 23: S208 - S219
26. Hocking RR. A Biometrics Invited Paper. The analysis and selection of variables in linear regression. Biometrics. 1976 ; 32: 1-49
27. Bowerman BL, O'Connell RT Linear statistical models: An applied approach. 2 nd ed.Belmont, CA: Duxbury, 1990. Belmont, CA: Duxbury ; 1990 :
28. Adhya S, Johnson G, Herbert J, et al. Pattern of hemodynamic impairment in multiple sclerosis: Dynamic susceptibility contrast perfusion MR imaging at 3.0 T. NeuroImage. 2006 ; 33: 1029-1035 (Pubitemid 44708796)
29. Inglese M, Park S-J, Johnson G, et al. Deep gray matter perfusion in multiple sclerosis: Dynamic susceptibility contrast perfusion magnetic resonance imaging at 3 T. Arch Neurol. 2007 ; 64: 196-202
30. Haselhorst R, Kappos L, Bilecen D, et al. Dynamic susceptibility contrast MR imaging of plaque development in multiple sclerosis: Application of an extended blood-brain barrier leakage correction. J Magn Reson Imaging. 2000 ; 11: 495-505 (Pubitemid 30252836)
31. Rashid W, Parkes LM, Ingle GT, et al. Abnormalities of cerebral perfusion in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2004 ; 75: 1288-1293 (Pubitemid 39141335)
32. Parkes LM, Rashid W, Chard DT, et al. Normal cerebral perfusion measurements using arterial spin labeling: Reproducibility, stability, and age and gender effects. Magn Reson Med. 2004 ; 51: 736-743 (Pubitemid 38420450)
33. Knutsson L, van Westen D, Petersen ET, et al. Absolute quantification of cerebral blood flow: Correlation between dynamic susceptibility contrast MRI and model-free arterial spin labeling. Magn Reson Imaging. 2010 ; 28: 1-7
34. Petersen ET, Lim T, Golay X. Model-free arterial spin labeling quantification approach for perfusion MRI. Magn Reson Med. 2006 ; 55: 219-232 (Pubitemid 43238088)
35. Petersen ET, Mouridsen K, Golay X. The QUASAR reproducibility study. Part II: Results from a multi-center Arterial Spin Labeling test-retest study. NeuroImage. 2010 ; 49: 104-113