QSAR study on 5-lipoxygenase inhibitors based on support vector machine

Medicinal Chemistry

Volumn 8, Issue 6, 2012, Pages 1108-1116

  Niu, Bing ^a   Su, Qiang ^a   Yuan, Xiaochen ^a   Lu, Wencong ^a   Ding, Juan ^b  

^a SHANGHAI UNIVERSITY   (China)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

1 phenyl 2H tetrahydro triazine 3 one analogues; Feature selection; Leave one out cross validation; Multiple linear regression (MLR); Partial least squares (PLS) analysis; Support vector regressions; Wrapper

Indexed keywords

1 PHENYL [2H] TETRAHYDRO TRIAZIN 3 ONE DERIVATIVE; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG STRUCTURE; ENZYME INHIBITION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SUPPORT VECTOR MACHINE;

ARACHIDONATE 5-LIPOXYGENASE; INHIBITORY CONCENTRATION 50; LEAST-SQUARES ANALYSIS; LINEAR MODELS; LIPOXYGENASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT VECTOR MACHINES;

EID: 84868004992     PISSN: 15734064     EISSN: 18756638     Source Type: Journal    
DOI: 10.2174/1573406411208061108     Document Type: Article

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