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Volumn 39, Issue 5, 2000, Pages 513-522

Changes in the Th1 or Th2 cytokine dominance in the synovium of rheumatoid arthritis (RA): A kinetic study of the Th subsets in one unusual RA patient

Author keywords

B cells; Rheumatoid arthritis; Th subsets; Th1 Th2

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 4; LYMPHOCYTE MEMBRANE IMMUNOGLOBULIN;

EID: 0034113234     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/39.5.513     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996;383:787-93.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 2
    • 0030963614 scopus 로고    scopus 로고
    • Induction of Th1 and Th2 CD4+ T cell responses: The alternative approaches
    • Constant SL, Bottomly K. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu Rev Immunol 1997;15:297-322.
    • (1997) Annu Rev Immunol , vol.15 , pp. 297-322
    • Constant, S.L.1    Bottomly, K.2
  • 3
    • 0030042868 scopus 로고    scopus 로고
    • Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development
    • Guler ML, Gorham JD. Hsieh CS et al. Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development. Science 1996;271:984-7.
    • (1996) Science , vol.271 , pp. 984-987
    • Guler, M.L.1    Gorham, J.D.2    Hsieh, C.S.3
  • 4
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 5
    • 0019195507 scopus 로고
    • Major anti-paternal alloantibody induced by murine pregnancy is non- complement-fixing IgG1
    • Bell SC, Billington WD. Major anti-paternal alloantibody induced by murine pregnancy is non- complement-fixing IgG1. Nature 1980;288:387-8.
    • (1980) Nature , vol.288 , pp. 387-388
    • Bell, S.C.1    Billington, W.D.2
  • 6
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate 1g isotype production
    • Snapper CM, Paul WE. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate 1g isotype production. Science 1987;236:944-7.
    • (1987) Science , vol.236 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 7
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • Paul WE, Seder RA. Lymphocyte responses and cytokines. Cell 1994;76:241-51.
    • (1994) Cell , vol.76 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2
  • 8
    • 0028275905 scopus 로고
    • Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection
    • Maggi E, Giudizi MG, Biagiotti R et al. Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection. J Exp Med 1994;180:489-95.
    • (1994) J Exp Med , vol.180 , pp. 489-495
    • Maggi, E.1    Giudizi, M.G.2    Biagiotti, R.3
  • 9
    • 0028960040 scopus 로고
    • Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines
    • Sad S, Marcotte R, Mosmann TR. Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. Immunity 1995;2:271-9.
    • (1995) Immunity , vol.2 , pp. 271-279
    • Sad, S.1    Marcotte, R.2    Mosmann, T.R.3
  • 10
    • 0032536869 scopus 로고    scopus 로고
    • Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
    • Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998;187:875-83.
    • (1998) J Exp Med , vol.187 , pp. 875-883
    • Sallusto, F.1    Lenig, D.2    Mackay, C.R.3    Lanzavecchia, A.4
  • 11
    • 0030769920 scopus 로고    scopus 로고
    • Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
    • Sallusto F, Mackay CR, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 1997;277:2005-7.
    • (1997) Science , vol.277 , pp. 2005-2007
    • Sallusto, F.1    Mackay, C.R.2    Lanzavecchia, A.3
  • 12
    • 0031963014 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
    • Bonecchi R, Bianchi G, Bordignon PP et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 1998;187:129-34.
    • (1998) J Exp Med , vol.187 , pp. 129-134
    • Bonecchi, R.1    Bianchi, G.2    Bordignon, P.P.3
  • 13
    • 0028982517 scopus 로고
    • Th1 and Th2 subsets: Paradigms lost?
    • Kelso A. Th1 and Th2 subsets: paradigms lost? Immunol Today 1995;16:374-9.
    • (1995) Immunol Today , vol.16 , pp. 374-379
    • Kelso, A.1
  • 14
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete G, De Carli M, Almerigogna F et al. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 1993;150:353-60.
    • (1993) J Immunol , vol.150 , pp. 353-360
    • Del Prete, G.1    De Carli, M.2    Almerigogna, F.3
  • 15
    • 0033083111 scopus 로고    scopus 로고
    • IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells
    • Aarvak T, Chabaud M, Miossec P, Natvig JB. IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J Immunol 1999;162:1246-51.
    • (1999) J Immunol , vol.162 , pp. 1246-1251
    • Aarvak, T.1    Chabaud, M.2    Miossec, P.3    Natvig, J.B.4
  • 16
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994;265:1237-40.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 17
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specitic T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M et al. A CD4+ T-cell subset inhibits antigen-specitic T-cell responses and prevents colitis. Nature 1997;389:737-42.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 18
    • 0024325070 scopus 로고
    • Heterogeneity of cytokine secretion patterns and functions of helper T cells
    • Mosmann TR, Coffman RL. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv Immunol 1989;46:111-47.
    • (1989) Adv Immunol , vol.46 , pp. 111-147
    • Mosmann, T.R.1    Coffman, R.L.2
  • 19
    • 0025923025 scopus 로고
    • Human TH1 and TH2 subsets: Doubt no more
    • Romagnani S. Human TH1 and TH2 subsets: doubt no more. Immunol Today 1991;12:256-7.
    • (1991) Immunol Today , vol.12 , pp. 256-257
    • Romagnani, S.1
  • 20
    • 0026024576 scopus 로고
    • Accumulation of Th-2-like helper T cells in the conjunctiva of patients with vernal conjunctivitis
    • Maggi E, Biswas P, Del Prete G et al. Accumulation of Th-2-like helper T cells in the conjunctiva of patients with vernal conjunctivitis. J Immunol 1991;146:1169-74.
    • (1991) J Immunol , vol.146 , pp. 1169-1174
    • Maggi, E.1    Biswas, P.2    Del Prete, G.3
  • 21
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994;12:227-57.
    • (1994) Annu Rev Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 22
    • 0027314092 scopus 로고
    • Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns
    • Quayle AJ, Chomarat P, Miossec P, Kjeldsen-Kragh J, Forre O, Natvig JB. Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns. Scand J Immunol 1993;38: 75-82.
    • (1993) Scand J Immunol , vol.38 , pp. 75-82
    • Quayle, A.J.1    Chomarat, P.2    Miossec, P.3    Kjeldsen-Kragh, J.4    Forre, O.5    Natvig, J.B.6
  • 23
    • 0023773031 scopus 로고
    • Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-I alpha
    • Buchan G, Barrett K, Turner M, Chantry D, Maini RN, Feldmann M. Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-I alpha. Clin Exp Immunol 1988;73:449-55.
    • (1988) Clin Exp Immunol , vol.73 , pp. 449-455
    • Buchan, G.1    Barrett, K.2    Turner, M.3    Chantry, D.4    Maini, R.N.5    Feldmann, M.6
  • 24
    • 0031445542 scopus 로고    scopus 로고
    • Th1/Th2 cytokine balance in arthritis
    • Miossec P, van den Berg W. Th1/Th2 cytokine balance in arthritis. Arthritis Rheum 1997;40:2105-15.
    • (1997) Arthritis Rheum , vol.40 , pp. 2105-2115
    • Miossec, P.1    Van Den Berg, W.2
  • 26
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis
    • Arend WP, Dayer JM. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum 1995;38:151-60.
    • (1995) Arthritis Rheum , vol.38 , pp. 151-160
    • Arend, W.P.1    Dayer, J.M.2
  • 29
    • 0025260626 scopus 로고
    • T gamma delta cells in juvenile rheumatoid arthritis and rheumatoid arthritis. In the juvenile rheumatoid arthritis synovium the T gamma delta cells express activation antigens and are predominantly V delta 1 + , and a significant proportion of these patients have elevated percentages of T gamma delta cells
    • Kjeldsen-Kragh J, Quayle A, Kalvenes C et al. T gamma delta cells in juvenile rheumatoid arthritis and rheumatoid arthritis. In the juvenile rheumatoid arthritis synovium the T gamma delta cells express activation antigens and are predominantly V delta 1 + , and a significant proportion of these patients have elevated percentages of T gamma delta cells. Scand J Immunol 1990;32:651-9.
    • (1990) Scand J Immunol , vol.32 , pp. 651-659
    • Kjeldsen-Kragh, J.1    Quayle, A.2    Kalvenes, C.3
  • 30
    • 0031700766 scopus 로고    scopus 로고
    • Increased production of a Th2 cytokine profile by activated whole blood cells from rheumatoid arthritis patients
    • Haddad A, Bienvenu J, Miossec P. Increased production of a Th2 cytokine profile by activated whole blood cells from rheumatoid arthritis patients. J Clin Immunol 1998;18:399-403.
    • (1998) J Clin Immunol , vol.18 , pp. 399-403
    • Haddad, A.1    Bienvenu, J.2    Miossec, P.3
  • 31
    • 0028409436 scopus 로고
    • A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity
    • Scott B, Liblau R, Degermann S et al. A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity 1994;1:73-83.
    • (1994) Immunity , vol.1 , pp. 73-83
    • Scott, B.1    Liblau, R.2    Degermann, S.3
  • 32
    • 0030009710 scopus 로고    scopus 로고
    • Bypassing the antigen to control rheumatoid arthritis
    • Miossec P, Chomarat P, Dechanet J. Bypassing the antigen to control rheumatoid arthritis. Immunol Today 1996; 17:170-3.
    • (1996) Immunol Today , vol.17 , pp. 170-173
    • Miossec, P.1    Chomarat, P.2    Dechanet, J.3
  • 33
    • 4244133581 scopus 로고    scopus 로고
    • Manipulation of the Th cytokine profile in CD4+ T cell subsets from inflammatory rheumatoid synovium
    • Aarvak T, Chabaud M, Miossec P, Natvig JB. Manipulation of the Th cytokine profile in CD4+ T cell subsets from inflammatory rheumatoid synovium. Arthritis Rheum (Suppl.)1998;41:S33.
    • (1998) Arthritis Rheum (Suppl.) , vol.41
    • Aarvak, T.1    Chabaud, M.2    Miossec, P.3    Natvig, J.B.4
  • 35
    • 0031059255 scopus 로고    scopus 로고
    • Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction
    • Joosten LA, Lubberts E, Durez P et al. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum 1997;40:249-60.
    • (1997) Arthritis Rheum , vol.40 , pp. 249-260
    • Joosten, L.A.1    Lubberts, E.2    Durez, P.3
  • 36
    • 10544238102 scopus 로고    scopus 로고
    • T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis
    • Scotet E, David-Ameline J, Peyrat MA et al. T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis. J Exp Med 1996;184:1791-1800.
    • (1996) J Exp Med , vol.184 , pp. 1791-1800
    • Scotet, E.1    David-Ameline, J.2    Peyrat, M.A.3
  • 37
    • 0030739650 scopus 로고    scopus 로고
    • Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease
    • Lafaille JJ, Keere FV, Hsu AL et al. Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease. J Exp Med 1997;186:307-12.
    • (1997) J Exp Med , vol.186 , pp. 307-312
    • Lafaille, J.J.1    Keere, F.V.2    Hsu, A.L.3
  • 38
    • 0028829010 scopus 로고
    • Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells
    • Khoruts A, Miller SD, Jenkins MK. Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells. J Immunol 1995;155:5011-7.
    • (1995) J Immunol , vol.155 , pp. 5011-5017
    • Khoruts, A.1    Miller, S.D.2    Jenkins, M.K.3
  • 39
    • 0031787636 scopus 로고    scopus 로고
    • Joint inflammation and cartilage destruction may occur uncoupled
    • van den Berg WB. Joint inflammation and cartilage destruction may occur uncoupled. Springer Semin Immunopathol 1998;20:149-64.
    • (1998) Springer Semin Immunopathol , vol.20 , pp. 149-164
    • Van Den Berg, W.B.1
  • 41
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo VK, Das MP, Brown JA et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995;80:707-18.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3
  • 42
    • 0028900297 scopus 로고
    • Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
    • Lenschow DJ, Ho SC, Sattar H et al. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med 1995;181:1145-55.
    • (1995) J Exp Med , vol.181 , pp. 1145-1155
    • Lenschow, D.J.1    Ho, S.C.2    Sattar, H.3
  • 43
    • 0030980997 scopus 로고    scopus 로고
    • Expansion of unusual CD4+ T cells in severe rheumatoid arthritis
    • Martens PB, Goronzy JJ, Schaid D, Weyand CM. Expansion of unusual CD4+ T cells in severe rheumatoid arthritis. Arthritis Rheum 1997;40:1106-14.
    • (1997) Arthritis Rheum , vol.40 , pp. 1106-1114
    • Martens, P.B.1    Goronzy, J.J.2    Schaid, D.3    Weyand, C.M.4
  • 44
    • 0031764104 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
    • Sallusto F, Lanzavecchia A, Mackay CR. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today 1998;19: 568-74.
    • (1998) Immunol Today , vol.19 , pp. 568-574
    • Sallusto, F.1    Lanzavecchia, A.2    Mackay, C.R.3
  • 45
    • 15844374279 scopus 로고    scopus 로고
    • Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
    • Shimoda K, van Deursen J, Sangster MY et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996;380:630-3.
    • (1996) Nature , vol.380 , pp. 630-633
    • Shimoda, K.1    Van Deursen, J.2    Sangster, M.Y.3


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