Associations between maternal genotypes and metabolites implicated in congenital heart defects

Molecular Genetics and Metabolism

Volumn 107, Issue 3, 2012, Pages 596-604

  Chowdhury, Shimul ^a,b   Hobbs, Charlotte A ^a   MacLeod, Stewart L ^a   Cleves, Mario A ^a   Melnyk, Stepan ^a   James, S Jill ^a   Hu, Ping ^a   Erickson, Stephen W ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b SACRED HEART MEDICAL CENTER   (United States)

Author keywords

Congenital heart defects (CHDs); Folate pathway; Maternal genotypes; Metabolites; Single nucleotide polymorphisms (SNPs)

Indexed keywords

CATALASE; FOLIC ACID; GLUTAMYLCYSTEINE; GLUTATHIONE; HOMOCYSTEINE; METHIONINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN; UNCLASSIFIED DRUG;

5,10 METHENYLTETRAHYDROFOLATE SYNTHETASE GENE; ADULT; AMINO ACID METABOLISM; ARTICLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; FEMALE; FOLIC ACID BLOOD LEVEL; GENE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GLUTATHIONE PEROXIDASE 6 GENE; HUMAN; HUMAN CELL; LIFESTYLE; MAJOR CLINICAL STUDY; METHIONINE ADENOSYLTRANSFERASE II ALPHA GENE; MULTIPLE LINEAR REGRESSION ANALYSIS; PREGNANCY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SINGLE NUCLEOTIDE POLYMORPHISM; TRNA ASPARTIC ACID METHYLTRANSFERASE 1 GENE; VITAMIN METABOLISM;

ADULT; ASYMPTOMATIC DISEASES; CARBON-NITROGEN LIGASES; CASE-CONTROL STUDIES; CATALASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; FOLIC ACID; GENOTYPE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEART DEFECTS, CONGENITAL; HOMOCYSTEINE; HUMANS; LIFE STYLE; MALE; METHIONINE; METHIONINE ADENOSYLTRANSFERASE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; TUMOR SUPPRESSOR PROTEINS;

EID: 84867901999     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2012.09.022     Document Type: Article

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