Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsia

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Hill, Lori D ^a   York, Timothy P ^a,b   Kusanovic, Juan P ^c,d,e   Gomez, Ricardo ^d,e   Eaves, Lindon J ^a,b   Romero, Roberto ^c   Strauss III, Jerome F ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d HOSPITAL DR SÓTERO DEL RÍO   (Chile)

^e PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CATECHOL METHYLTRANSFERASE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2);

ADULT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EPISTASIS; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; OBESITY; PREECLAMPSIA; PROTEIN PROTEIN INTERACTION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; ANIMAL; GENETIC EPISTASIS; GENETICS; HISPANIC; MOUSE; PREGNANCY;

MUS;

ALLELES; ANIMALS; CATECHOL O-METHYLTRANSFERASE; EPISTASIS, GENETIC; FEMALE; HAPLOTYPES; HISPANIC AMERICANS; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRE-ECLAMPSIA; PREGNANCY;

EID: 79551648295     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016681     Document Type: Article

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