β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: A role in the chemopreventive efficacy of aspirin

British Journal of Cancer

Volumn 107, Issue 9, 2012, Pages 1514-1517

  Smartt, H J M ^a   Greenhough, A ^a   Ordonez Moran P ^b   Al Kharusi, M ^a   Collard, T J ^a   Mariadason, J M ^c   Huelsken, J ^b   Williams, A C ^a   Paraskeva, C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b EPFL   (Switzerland)

^c AUSTIN HOSPITAL   (Australia)

Author keywords

15 PGDH; aspirin; b catenin; colorectal cancer prevention; PGE2; PGT

Indexed keywords

ACETYLSALICYLIC ACID; BETA CATENIN; CARRIER PROTEIN; PROSTAGLANDIN; PROSTAGLANDIN TRANSPORTER PGT; SMALL INTERFERING RNA; TAMOXIFEN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL TISSUE; ARTICLE; CHEMOPROPHYLAXIS; COLORECTAL TUMOR; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SELF CONCEPT; TUMOR CELL; UPREGULATION;

ANIMALS; ANTICARCINOGENIC AGENTS; ASPIRIN; BETA CATENIN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; HCT116 CELLS; HT29 CELLS; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; INTESTINAL MUCOSA; MICE; ORGANIC ANION TRANSPORTERS; SIGNAL TRANSDUCTION;

EID: 84867895532     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.430     Document Type: Article

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