Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 2, 2012, Pages 401-409

  Tao, Xiao Mei ^a,b   Wang, Jian Cheng ^b   Wang, Jia Bao ^a   Feng, Qiang ^b   Gao, Shan Yun ^b   Zhang, Liang Ren ^b   Zhang, Qiang ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Anticancer activity; Conjugated linoleic acid; Gemcitabine; Prodrug

Indexed keywords

CONJUGATED LINOLEIC ACID; DIPYRIDAMOLE; GEMCITABINE; NITROBENZYLTHIOINOSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL AVAILABILITY; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; DEOXYCYTIDINE; DRUG STABILITY; FEMALE; HALF-LIFE; HUMANS; LINOLEIC ACID; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; NUCLEOSIDE TRANSPORT PROTEINS; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84867856439     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.06.007     Document Type: Article

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