Antioxidant/antibacterial activities of a topical phytopharmaceutical formulation containing a standardized extract of baccharis incarum, an extremophile plant species from argentine Puna

Phytotherapy Research

Volumn 26, Issue 11, 2012, Pages 1759-1767

  Nuño, Gabriela ^a   Zampini, Iris C ^a   Ordoñez, Roxana M ^a   Alberto, María R ^a   Arias, Myriam E ^a   Isla, María I ^a  

^a UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

Author keywords

antibacterial activity; Baccharis incarum; phenolic compounds; phytohydrogel; radical scavenging activity

Indexed keywords

2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); 4',5 DIHYDROXY 3',3,6,7,8 PENTAMETHOXYFLAVONE; ALCOHOL; AMPICILLIN; ANTIINFECTIVE AGENT; ANTIOXIDANT; BACCHARIS INCARUM EXTRACT; CARBOPOL 934; CHLOROGENIC ACID; FC RECEPTOR; FLAVONE DERIVATIVE; GENTAMICIN; METICILLIN; OXACILLIN; PLANT EXTRACT; STREPTOMYCIN; TRIETHANOLAMINE; UNCLASSIFIED DRUG; VANCOMYCIN;

AGAR DIFFUSION; ANALYTICAL EQUIPMENT; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIOXIDANT ACTIVITY; ARGENTINA; ARTICLE; BACCHARIS; BACCHARIS INCARUM; BACTERIUM ISOLATE; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG FORMULATION; DRUG INDICATION; DRUG PENETRATION; DRUG QUALITY; DRUG RELEASE; DRUG SAFETY; DRUG STABILITY; DRUG STORAGE; ENTEROCOCCUS FAECALIS; FRANZ DIFFUSION CELL; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; QUALITY CONTROL; ROOM TEMPERATURE; SALMONELLA; SKIN INFECTION; SOFT TISSUE INFECTION; STANDARDIZATION; STAPHYLOCOCCUS AUREUS; TINCTURE; TOPICAL DRUG ADMINISTRATION;

ACRYLATES; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; BACCHARIS; ENTEROCOCCUS FAECALIS; MICROBIAL SENSITIVITY TESTS; PLANT EXTRACTS; STAPHYLOCOCCUS AUREUS;

BACCHARIS; BACCHARIS INCARUM; ENTEROCOCCUS FAECALIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; SALMONELLA; STAPHYLOCOCCUS AUREUS;

EID: 84867853941     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4633     Document Type: Article

References (34)

1. Abad MJ, Bermejo P,. 2007. Baccharis (Compositae): a review update. Arkivoc 7: 76-96.
2. Alberto MR, Zampini IC, Isla MI,. 2009. Inhibition of cyclooxygenase activity by standarized hydroalcoholic extracts of for Asteraceae species from the Argentine Puna. Braz J Med Biol Res 42: 787-790.
3. Aqil F, Ahmad I, Owais M,. 2006. Evaluation of anti-methicillin-resistant Staphylococcus aureus (MRSA) activity and synergy of some bioactive plant extracts. J Biotechnol 1: 1093-1102.
4. Cardozo ML, Ordóñez RM, Zampini IC, Cuello S, Dibenedetto G, Isla MI,. 2010. Evaluation of antioxidant capacity, genotoxicity and polyphenol content of non conventional foods: Prosopis flours. Food Res Int 43: 1505-1510.
5. Castro M, Villagrán C, Arroyo M,. 1982. Estudio Etnobotánico en la precordillera y altiplano de Los Andes del norte de Chile (18-19Â S). In El Hombre y los Ecosistemas de Montañas Vol 2, Veloso A, &, Bustos E, (eds). UNESCO: Rostlac, Montevideo, Uruguay, 133-203.
6. Clinical and Laboratory Standards Institute. 2006. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Approved Standard. Seventh Edition document M7-A7.
7. Cos P, Vlietinck A, Vanden Berghe D, Maes L,. 2006. Anti-infective potential of natural products: How to develop a stronger in vitro 'proof-of-concept'. J Ethnopharmacol 106: 290-302.
8. Current Good Manufacturing Practice. 1996. Final Rule, 21 CFR Parts 808, 812 and 820; Quality System Regulation for Medical Devices.
9. Farmacopea Argentina Codex Medicamentarius Argentino. 1978. 6. ed. Buenos Aires, Argentina.
10. Farmacopea Española. 1997. 1. ed. Publicado por Ministerio de Sanidad y Consumo: Madrid, 86-93.
11. Fuchs J, Packer L,. 1991. Photooxidative stress in the skin. In Oxidative stress -oxidants and antioxidants, Sies H, (ed.). Academic Press: London, 559-583.
12. Getie M, Gebre-Mariam T, Rietz R, Neubert RH,. 2002. Evaluation of the release profiles of flavonoids from topical formulations of the crude extract of the leaves of Dodonea viscosa (Sapindaceae). Pharmazie 57: 320-322.
13. Hemaiswary S, Kruthiventi A, Doble M,. 2008. Synergism between natural products and antibiotics against infectious diseases. Phytomedicine 15: 639-652.
14. Jarrar N, Abu-Hijleh A, Adwan LK,. 2010. Antibacterial activity of Rosmarinus officinalis alone and in combination with cefuroxime against methicillin-resistant Staphylococcus aureus. Asian Pac J Trop Med 3: 121-123.
15. Ma XH, Zheng CJ, Han LY, et al,. 2009. Synergistic therapeutic actions of herbal ingredients and their mechanisms from molecular interaction and network perspectives. Drug Discov Today 14: 11-12.
16. Maron DM, Ames BN,. 1983. Revised methods for the Salmonella mutagenicity test. Mutat Res 113: 173-215.
17. Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH,. 1999. Manual of Clinical Microbiology, Vol. 6. ASM: Washington, DC.
18. Nieva Moreno MI, Isla MI, Cudmani NG, Vattuone MA, Sampietro AR,. 1999. Screening of antibacterial activity of Amaicha del Valle (Tucumán, Argentina) propolis. J Ethnopharmacol 68: 97-102.
19. Ordóñez AA, Ordóñez RM, Zampini IC, Isla MI,. 2009. Design and quality control of a pharmaceutical formulation containing natural products with antibacterial, antifungal and antioxidant properties. Int J Pharm 378: 51-58.
20. Ordóñez RM, Cardozo ML, Zampini IC, Isla MI,. 2010. Evaluation of antioxidant activity and genotoxicity of alcoholic and aqueous beverages and pomace derived from ripe fruits of Cyphomandra betacea Sendt. J Agric Food Chem 58: 331-337.
21. Peppas NA, Huang Y, Torres-Lugo M, Ward JH, Zhang J,. 2000. Physicochemical foundations and structural design of hydrogels in medicine and biology. Annu Rev Biomed Eng 2: 9-29.
22. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C,. 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26: 1231-1237.
23. Rios J, Recio M,. 2005. Perspective paper medicinal plants and antimicrobial activity. J Ethnopharmacol 100: 80-84.
24. Rodríguez Noriega E, Seas C, Guzmán Blanco M, et al,. 2010. Evolution of methicillin-resistant Staphylococcus aureus clones in Latin America. Int J Infect Dis 14: 560-566.
25. Singleton V, Orthofer R, Lamuela-Raventos R,. 1999. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin Ciocalteau reagent. Methods Enzymol 299: 152-178.
26. The United States Pharmacopeia XXIII, 1995.
27. Wagner H, Bladt S, Zgainsky E,. 1984. Plant Drug Analysis: A Thin Layer Chromatography. Springer: Berlín, Germany.
28. Wagner H, Ulrich-Merzenich G,. 2009. Synergy research: Approaching a new generation of phytopharmaceuticals. Phytomedicine 16: 97-110.
29. Wickens G,. 1993. Vegetation and ethnobotany of the Atacama desert and adjacent Andes in northern Chile. Opera Bot 121: 291-307.
30. Woisky RG, Salatino A,. 1998. Analysis of propolis: some parameters and procedures for chemical quality control. J Apicult Res 37: 99-105.
31. Zampini IC,. 2009. Bioactividades de especies vegetales de la familia Asteraceae que crecen en zonas extremas (Antofagasta de la Sierra, Catamarca, Argentina). Aislamiento de metabolitos con potenciales aplicaciones en la industria farmacéutica-alimenticia y en agricultura. PhD thesis. Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Argentina.
32. Zampini IC, Isla MI, Schmeda-Hirschmann G,. 2009. Antimicrobial and antioxidant compounds from the infusion and methanolic extract of Baccharis incarum (Wedd.) Perkins. J Chil Chem Soc 54: 289-293.
33. Zampini IC, Meson Gana J, Ordoñez RM, Sayago JE, Nieva Moreno MI, Isla MI,. 2008. Antioxidant and xanthine oxidase inhibitory activities of plant species from the Argentine Puna (Antofagasta, Catamarca). Rec Prog Med Plants 21: 95-110.
34. •+ immobilized by gel entrapment. AAPS Pharm Sci Tech 11: 1159-1163.