Chemokine/chemokine receptor interactions contribute to the accumulation of Th17 cells in patients with esophageal squamous cell carcinoma

Human Immunology

Volumn 73, Issue 11, 2012, Pages 1068-1072

  Chen, Deyu ^a   Jiang, Riyue ^a   Mao, Chaoming ^b   Shi, Liang ^b   Wang, Shengjun ^b   Yu, Lichao ^a   Hu, Qin ^a   Dai, Dongfang ^a   Xu, Huaxi ^b  

^a AFFILIATED HOSPITAL OF JIANGSU UNIVERSITY   (China)

^b JIANGSU UNIVERSITY   (China)

Author keywords

Chemokine; Chemokine receptor; Esophageal squamous cell carcinoma; Th17 cells

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR6; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER SURGERY; CELL MIGRATION; CELLULAR DISTRIBUTION; CHEMOTAXIS; CONTROLLED STUDY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TH17 CELL;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; CHEMOKINES; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; IMMUNOPHENOTYPING; MALE; MIDDLE AGED; NEOPLASM STAGING; PROTEIN BINDING; RECEPTORS, CCR2; RECEPTORS, CCR4; RECEPTORS, CCR6; RECEPTORS, CHEMOKINE; TH17 CELLS;

EID: 84867844208     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2012.07.333     Document Type: Article

References (38)

1. + T cells in anti-tumor immune responses. Immunol Rev 2008, 222:129-144.
2. Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006, 441(7090):235-238.
3. Leipe J., Grunke M., Dechant C., Reindl C., Kerzendorf U., Schulze-Koops H., et al. Role of Th17 cells in human autoimmune arthritis. Arthritis Rheum 2010, 62(10):2876-2885.
4. Strober W., Zhang F., Kitani A., Fuss I., Fichtner-Feigl S. Proinflammatory cytokines underlying the inflammation of Crohn's disease. Curr Opin Gastroenterol 2010, 26(4):310-317.
5. Brucklacher-Waldert V., Stuerner K., Kolster M., Wolthausen J., Tolosa E. Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis. Brain 2009, 132(Pt 12):3329-3341.
6. Zhang J.Y., Zhang Z., Lin F., Zou Z.S., Xu R.N., Jin L., et al. Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology 2010, 51(1):81-91.
7. Zhang J.P., Yan J., Xu J., Pang X.H., Chen M.S., Li L., et al. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol 2009, 50(5):980-989.
8. Maruyama T., Kono K., Mizukami Y., Kawaguchi Y., Mimura K., Watanabe M., et al. Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer. Cancer Sci 2010, 101(9):1947-1954.
9. Su X., Ye J., Hsueh E.C., Zhang Y., Hoft D.F., Peng G. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol 2010, 184(3):1630-1641.
10. Wang D., Dubois R.N., Richmond A. The role of chemokines in intestinal inflammation and cancer. Curr Opin Pharmacol 2009, 9(6):688-696.
11. Gu D., Chen Z., Zhao H., Du W., Xue F., Ge J., et al. Th1 (CXCL10) and Th2 (CCL2) chemokine expression in patients with immune thrombocytopenia. Hum Immunol 2010, 71(6):586-591.
12. Hoglund R.A., Hestvik A.L., Holmoy T., Maghazachi A.A. Expression and functional activity of chemokine receptors in glatiramer acetate-specific T cells isolated from multiple sclerosis patient receiving the drug glatiramer acetate. Hum Immunol 2011, 72(2):124-134.
13. Gao P., Zhou X.Y., Yashiro-Ohtani Y., Yang Y.F., Sugimoto N., Ono S., et al. The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3. J Leukoc Biol 2003, 73(2):273-280.
14. Loetscher P., Uguccioni M., Bordoli L., Baggiolini M., Moser B., Chizzolini C., et al. CCR5 is characteristic of Th1 lymphocytes. Nature 1998, 391(6665):344-345.
15. Sallusto F., Lenig D., Mackay C.R., Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998, 187(6):875-883.
16. Bonecchi R., Bianchi G., Bordignon P.P., D'Ambrosio D., Lang R., Borsatti A., et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s and Th2s). J Exp Med 1998, 187(1):129-134.
17. Zingoni A., Soto H., Hedrick J.A., Stoppacciaro A., Storlazzi C.T., Sinigaglia F., et al. The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J Immunol 1998, 161(2):547-551.
18. Iellem A., Mariani M., Lang R., Recalde H., Panina-Bordignon P., Sinigaglia F., et al. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med 2001, 194(6):847-853.
19. Cavassani K.A., Campanelli A.P., Moreira A.P., Vancim J.O., Vitali L.H., Mamede R.C., et al. Systemic and local characterization of regulatory T cells in a chronic fungal infection in humans. J Immunol 2006, 177(9):5811-5818.
20. Sato W., Aranami T., Yamamura T. Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype. J Immunol 2007, 178(12):7525-7529.
21. Acosta-Rodriguez E.V., Rivino L., Geginat J., Jarrossay D., Gattorno M., Lanzavecchia A., et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007, 8(6):639-646.
22. Maniati E., Soper R., Hagemann T. Up for Mischief? IL-17/Th17 in the tumour microenvironment. Oncogene 2010, 29(42):5653-5662.
23. Murugaiyan G., Saha B. Protumor vs antitumor functions of IL-17. J Immunol 2009, 183(7):4169-4175.
24. Martin-Orozco N., Dong C. The IL-17/IL-23 axis of inflammation in cancer: friend or foe?. Curr Opin Invest Drugs 2009, 10(6):543-549.
25. Kryczek I., Banerjee M., Cheng P., Vatan L., Szeliga W., Wei S., et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009, 114(6):1141-1149.
26. Lv L., Pan K., Li X.D., She K.L., Zhao J.J., Wang W., et al. The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma. PLoS One 2011, 6(3):e18219.
27. Sfanos K.S., Bruno T.C., Maris C.H., Xu L., Thoburn C.J., DeMarzo A.M., et al. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clin Cancer Res 2008, 14(11):3254-3261.
28. Zhang B., Rong G., Wei H., Zhang M., Bi J., Ma L., et al. The prevalence of Th17 cells in patients with gastric cancer. Biochem Biophys Res Commun 2008, 374(3):533-537.
29. Miyahara Y., Odunsi K., Chen W., Peng G., Matsuzaki J., Wang R.F. Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer. Proc Natl Acad Sci U S A. 2008, 105(40):15505-15510.
30. Liu J., Duan Y., Cheng X., Chen X., Xie W., Long H., et al. IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. Biochem Biophys Res Commun 2011, 407(2):348-354.
31. Volpe E., Servant N., Zollinger R., Bogiatzi S.I., Hupe P., Barillot E., et al. A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat Immunol 2008, 9(6):650-657.
32. Manel N., Unutmaz D., Littman D.R. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008, 9(6):641-649.
33. Yang L., Anderson D.E., Baecher-Allan C., Hastings W.D., Bettelli E., Oukka M., et al. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 2008, 454(7202):350-352.
34. Singh S.P., Zhang H.H., Foley J.F., Hedrick M.N., Farber J.M. Human T cells that are able to produce IL-17 express the chemokine receptor CCR6. J Immunol 2008, 180(1):214-221.
35. + regulatory T cells. J Immunol 2008, 180(1):122-129.
36. Webb A., Johnson A., Fortunato M., Platt A., Crabbe T., Christie M.I., et al. Evidence for PI-3K-dependent migration of Th17-polarized cells in response to CCR2 and CCR6 agonists. J Leukoc Biol 2008, 84(4):1202-1212.
37. Pelletier M., Maggi L., Micheletti A., Lazzeri E., Tamassia N., Costantini C., et al. Evidence for a cross-talk between human neutrophils and Th17 cells. Blood 2010, 115(2):335-343.
38. + T cells in malignant pleural effusion. J Immunol 2010, 185(10):6348-6354.