Constant domain-regulated antibody catalysis

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 36096-36104

  Sapparapu, Gopal ^a,b   Planque, Stephanie ^a   Mitsuda, Yukie ^a   McLean, Gary ^a,c   Nishiyama, Yasuhiro ^a   Paul, Sudhir ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c LONDON METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC FUNCTIONS; CATALYTIC MECHANISMS; CATALYTIC SITES; DIESTERS; HEAVY AND LIGHT CHAINS; HIGH AFFINITY; HYDROLYTIC ACTIVITIES; HYDROLYTIC REACTIONS; IMMUNE FUNCTION; MODEL PEPTIDES; NONCOVALENT; PHOSPHONATES; POLYCLONAL; POLYCLONAL IGG; STRUCTURAL BASIS;

AMIDES; CATALYSIS; CATALYST ACTIVITY; HYDROLYSIS; PEPTIDES; QUANTUM CHEMISTRY; SCAFFOLDS;

ANTIBODIES;

EPITOPE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; RECOMBINANT ANTIBODY; SCAFFOLD PROTEIN;

ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ARTICLE; CATALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENE REARRANGEMENT; HEAVY CHAIN; HUMAN; HYDROLYSIS; LIGHT CHAIN; MOLECULAR MODEL; NUCLEOPHILICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY MECHANISM; STRUCTURE ACTIVITY RELATION;

ADOLESCENT; ADULT; AGED; AMINO ACID SEQUENCE; ANTIBODIES, CATALYTIC; ANTIBODIES, MONOCLONAL; CATALYTIC DOMAIN; FEMALE; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA;

EID: 84867837936     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.401075     Document Type: Article

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