Effects of strychnine on the potassium conductance of the frog node of ranvier

Journal of General Physiology

Volumn 69, Issue 6, 1977, Pages 897-914

  Shapiro, B I ^a,b,c  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM; QUATERNARY AMMONIUM DERIVATIVE; STRYCHNINE; TETRODOTOXIN;

AXOPLASM FLOW; DEPOLARIZATION; FROG; N METHYLSTRYCHNINE; NERVE CELL; NERVE CELL MEMBRANE POTENTIAL; PHARMACOKINETICS; POTASSIUM CHANNEL; RANVIER NODE; STATISTICS; STRYCHNINE DERIVATIVE; TETRAETHYLAMMONIUM COMPOUND; THEORETICAL STUDY;

ACTION POTENTIALS; ANIMAL; ANURA; IN VITRO; NEURAL CONDUCTION; POTASSIUM; RANA PIPIENS; RANVIER'S NODES; STRYCHNINE; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0017644692     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.69.6.897     Document Type: Article

References (12)

1. Armstrong, C. M. 1969. Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons. J. Gen. Physiol. 54: 553-575.
2. Armstrong, C. M. 1971. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons. J. Gen. Physiol. 58: 413-437.
3. Armstrong, C. M. 1975. Potassium pores of nerve and muscle membranes. In Membranes. Lipid Bilayers and Biological Membranes: Dynamic Properties. G. Eisenman, editor. Marcel Dekker, Inc., New York. 3: 325-358.
4. Armstrong, C. M., and B. Hille. 1972. The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier. J. Gen. Physiol. 59: 388-400.
5. Dodge, F. A., and B. Frankenhaeuser. 1958. Membrane currents in isolated frog nerve fibre under voltage clamp conditions. J. Physiol. (Lond.). 143: 76-90.
6. Frankenhaeuser, B. 1962. Delayed currents in myelinated nerve fibres of Xenopus laetris investigated with voltage clamp technique. J. Physiol. (Lond.). 160: 40-45.
7. Hille, B. 1971. The permeability of the sodium channel to organic cations in myelinated nerve. J. Gen. Physiol. 58: 599-619.
8. Hille, B. 1975a. Ionic selectivity of Na and K channels of nerve membranes. In Membranes. Lipid Bilayers and Biological Membranes: Dynamic Properties. G. Eisenman, editor. Marcel Dekker, Inc., New York. 3: 255-323.
9. Hille, B. 1975b. Ionic selectivity, saturation, and block in sodium channels. A four-barrier model. J. Gen. Physiol. 66: 535-560.
10. Maruhashi, J., H. Totani, H. Takahashi, and M. Yamada. 1956. On the effects of strychnine upon myelinated nerve fibers of toads. Jpn. J. Physiol. 6: 175-191.
11. Shapiro, B. I., C. M. Wang, and T. Narahashi. 1974. Effects of strychnine on ionic conductances of squid axon membrane. J. Pharmacol. Exp. Ther. 188: 66-76.
12. Woodhull, A. M. 1973. Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61: 687-708.