P6981, an arylstibonic acid, is a novel low nanomolar inhibitor of cAMP response element-binding protein binding to DNA

Molecular Pharmacology

Volumn 82, Issue 5, 2012, Pages 814-823

  Zhao, Jianfei ^a   Stagno, Jason R ^b   Varticovski, Lyuba ^a   Nimako, Eric ^a   Rishi, Vikas ^a,e   McKinnon, Kathy ^a   Akee, Rhone ^c   Shoemaker, Robert H ^d   Ji, Xinhua ^b   Vinson, Charles ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

^d FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^e NATIONAL AGRI FOOD BIOTECHNOLOGY INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 STIBONOPHENYL)MALONIC ACID; ANTIMONY; ANTINEOPLASTIC AGENT; ARGININE; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CARBOXYLIC ACID DERIVATIVE; CCAAT ENHANCER BINDING PROTEIN; CHIMERIC PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOSTATIC AGENT; GREEN FLUORESCENT PROTEIN; LEUCINE ZIPPER PROTEIN; MALONIC ACID DERIVATIVE; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; NSC 13788; PROTEIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG; UPSTREAM STIMULATING FACTOR; VITELLOGENIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CIRCULAR DICHROISM; CLEAR CELL CARCINOMA; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPLASM; DENATURATION; DNA BINDING; DNA SEQUENCE; GEL MOBILITY SHIFT ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; STATIC ELECTRICITY; STRUCTURE ACTIVITY RELATION; THERMAL ANALYSIS;

ACIDS, NONCARBOXYLIC; ANIMALS; ANTIMONY; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL CYCLE CHECKPOINTS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CINNAMATES; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; LEUCINE ZIPPERS; MICE; MICE, SCID; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PROTEIN DENATURATION; TRANSPLANTATION, HETEROLOGOUS; VITELLOGENINS;

EID: 84867814443     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.080820     Document Type: Article

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