Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon

Biochemical Journal

Volumn 448, Issue 1, 2012, Pages 1-11

  Coldwell, Mark J ^a,b   Sack, Ulrike ^a   Cowan, Joanne L ^a,b   Barrett, Rachel M ^a   Vlasak, Markete ^a   Sivakumaran, Keiley ^a   Morley, Simon J ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Alternative splicing; Eukaryotic initiation factor; Non canonical initiation codon; Translation initiation

Indexed keywords

CASPASE 3; INITIATION FACTOR 4G; INITIATION FACTOR 4GII; MESSENGER RNA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; START CODON;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CODON, INITIATOR; DNA, COMPLEMENTARY; EUKARYOTIC INITIATION FACTOR-4G; EXONS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; OPEN READING FRAMES; PROMOTER REGIONS, GENETIC; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; RNA SPLICE SITES; RNA STABILITY; RNA, MESSENGER; RNA, SMALL INTERFERING; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84867806665     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111765     Document Type: Article

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