The impact of mutation and gene conversion on the local diversification of antigen genes in African trypanosomes

Molecular Biology and Evolution

Volumn 29, Issue 11, 2012, Pages 3321-3331

  Gjini, Erida ^a   Haydon, Daniel T ^a,b   Barry, J David ^b   Cobbold, Christina A ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

African trypanosome; diversification; gene conversion; hidden Markov model; multigene families; point mutation; VSG archive

Indexed keywords

VARIANT SURFACE GLYCOPROTEIN;

AFRICA; AFRICAN TRYPANOSOMIASIS; AMINO ACID SEQUENCE; ARTICLE; BAYES THEOREM; GENE CLUSTER; GENE CONVERSION; GENE IDENTIFICATION; GENE MUTATION; GENETIC VARIABILITY; HIDDEN MARKOV MODEL; INFORMATION CENTER; MISMATCH REPAIR; MOLECULAR MODEL; NONHUMAN; POINT MUTATION; TRYPANOSOMA;

ANTIGENIC VARIATION; ANTIGENS, PROTOZOAN; GENE CONVERSION; GENES, PROTOZOAN; HUMANS; MODELS, GENETIC; MUTATION; PHYLOGENY; TIME FACTORS; TRYPANOSOMA; TRYPANOSOMIASIS, AFRICAN;

EID: 84867800613     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mss166     Document Type: Article

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