Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress

Toxicological Sciences

Volumn 130, Issue 1, 2012, Pages 17-32

  Hsieh, Tusty Jiuan ^a   Hsieh, Pei Chen ^b   Tsai, Yi Hong ^c   Wu, Chia Fang ^b   Liu, Chia Chu ^d   Lin, Ming Yen ^b   Wu, Ming Tsang ^b,d,e  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b Department of Public Health ^*  (Taiwan)

^c Graduate Institute of Natural Products   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Caspase; Fibronectin; Inflammation; MAPK; NF kB

Indexed keywords

CASPASE 3; CASPASE 9; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MELAMINE; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR CELL ADHESION MOLECULE 1;

APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; RISK FACTOR;

APOPTOSIS; CELL LINE; CELL NUCLEUS; CHEMOKINE CCL2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FIBRONECTINS; FOOD CONTAMINATION; GENE EXPRESSION; HUMANS; INTERLEUKIN-6; KIDNEY TUBULES, PROXIMAL; OXIDATIVE STRESS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TRIAZINES; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84867800537     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs231     Document Type: Article

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