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Volumn , Issue , 2006, Pages 486-495

Basis of antibody imaging and therapy

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EID: 84867787150     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-540-47953-6_19     Document Type: Chapter
Times cited : (1)

References (132)
  • 1
    • 0024694268 scopus 로고
    • Practical consideration in the production, purification, and formulation of monoclonal antibodies for immunoscintigraphy and immunotherapy
    • Bogard WC Jr, Dean RT, Deo Y, Fuchs R, Mattis JA, McLean AA, et al (1989) Practical consideration in the production, purification, and formulation of monoclonal antibodies for immunoscintigraphy and immunotherapy. Semin Nucl Med 19:202-220
    • (1989) Semin Nucl Med , vol.19 , pp. 202-220
    • Bogard Jr., W.C.1    Dean, R.T.2    Deo, Y.3    Fuchs, R.4    Mattis, J.A.5    McLean, A.A.6
  • 2
    • 0025023277 scopus 로고
    • Recent developments in the radiola-beling of antibodies with iodine, indium, and technetium
    • Hnatowich DJ (1990) Recent developments in the radiola-beling of antibodies with iodine, indium, and technetium. Semin Nucl Med 20:80-91
    • (1990) Semin Nucl Med , vol.20 , pp. 80-91
    • Hnatowich, D.J.1
  • 3
    • 0027755990 scopus 로고
    • Search for new and improved radiola-beling methods for monoclonal antibodies
    • Hiltunen JV (1993) Search for new and improved radiola-beling methods for monoclonal antibodies. Acta Oncol 32:831-839
    • (1993) Acta Oncol , vol.32 , pp. 831-839
    • Hiltunen, J.V.1
  • 4
    • 0027342527 scopus 로고
    • New approaches to radiola-beling monoclonal antibodies
    • Zimmer AM, Spies SM (1993) New approaches to radiola-beling monoclonal antibodies. Cancer Treat Res 68:99-109
    • (1993) Cancer Treat Res , vol.68 , pp. 99-109
    • Zimmer, A.M.1    Spies, S.M.2
  • 5
    • 14844359242 scopus 로고    scopus 로고
    • Radiobiologic principles in radionuclide therapy
    • Kassis AI, Adelstein SJ (2005) Radiobiologic principles in radionuclide therapy. J Nucl Med 46 Suppl 1:4S-12S
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Kassis, A.I.1    Adelstein, S.J.2
  • 6
    • 0030948131 scopus 로고    scopus 로고
    • Trials and tribulations: Oncological antibody imaging comes to the fore
    • Zuckier LS, DeNardo GL (1997) Trials and tribulations: oncological antibody imaging comes to the fore. Semin Nucl Med 27:10-29
    • (1997) Semin Nucl Med , vol.27 , pp. 10-29
    • Zuckier, L.S.1    Denardo, G.L.2
  • 7
    • 0032706773 scopus 로고    scopus 로고
    • Clinical experience with radiolabelled monoclonal antibodies in the detection of colorectal and ovarian carcinoma recurrence and review of the literature
    • Pinkas L, Robins PD, Forstrom LA, Mahoney DW, Mullan BP (1999) Clinical experience with radiolabelled monoclonal antibodies in the detection of colorectal and ovarian carcinoma recurrence and review of the literature. Nucl Med Commun 20:689-696
    • (1999) Nucl Med Commun , vol.20 , pp. 689-696
    • Pinkas, L.1    Robins, P.D.2    Forstrom, L.A.3    Mahoney, D.W.4    Mullan, B.P.5
  • 8
    • 0032890674 scopus 로고    scopus 로고
    • Breast cancer imaging with radiolabeled antibodies
    • Goldenberg DM, Nabi HA (1999) Breast cancer imaging with radiolabeled antibodies. Semin Nucl Med 29:41-48
    • (1999) Semin Nucl Med , vol.29 , pp. 41-48
    • Goldenberg, D.M.1    Nabi, H.A.2
  • 9
    • 14844359240 scopus 로고    scopus 로고
    • Current status of therapy of solid tumors
    • Jhanwar YS, Divgi C (2005) Current status of therapy of solid tumors. J Nucl Med 46 Suppl 1:141S-150S
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Jhanwar, Y.S.1    Divgi, C.2
  • 10
    • 14844343723 scopus 로고    scopus 로고
    • Perspectives on cancer therapy with radiolabeled monoclonal antibodies
    • Sharkey RM, Goldenberg DM (2005) Perspectives on cancer therapy with radiolabeled monoclonal antibodies. J Nucl Med 46 Suppl 1:115S-127S
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 11
    • 0018182545 scopus 로고
    • Immunoglobulin structure and effector functions
    • Winkelhake JL (1978) Immunoglobulin structure and effector functions. Immunochemistry 15:695-714
    • (1978) Immunochemistry , vol.15 , pp. 695-714
    • Winkelhake, J.L.1
  • 12
    • 0021857415 scopus 로고
    • Immunoglobulin G: Functional sites
    • Burton DR (1985) Immunoglobulin G: functional sites. Mol Immunol 22:161-206
    • (1985) Mol Immunol , vol.22 , pp. 161-206
    • Burton, D.R.1
  • 13
    • 0029553186 scopus 로고
    • The effector functions of immu-noglobulins: Implications for therapy
    • Ward ES, Ghetie V (1995) The effector functions of immu-noglobulins: implications for therapy. Ther Immunol 2:77-94
    • (1995) Ther Immunol , vol.2 , pp. 77-94
    • Ward, E.S.1    Ghetie, V.2
  • 14
    • 0024698430 scopus 로고
    • Immunolog-ic and pharmacologic concepts of monoclonal antibodies
    • Zuckier LS, Rodriguez LD, Scharff MD (1989) Immunolog-ic and pharmacologic concepts of monoclonal antibodies. Semin Nucl Med 19:166-186
    • (1989) Semin Nucl Med , vol.19 , pp. 166-186
    • Zuckier, L.S.1    Rodriguez, L.D.2    Scharff, M.D.3
  • 15
    • 0032170063 scopus 로고    scopus 로고
    • Chimeric human-mouse IgG antibodies with shuffled constant region exons demonstrate that multiple domains contribute to in vivo half-life
    • Zuckier LS, Chang CJ, Scharff MD, Morrison SL (1998) Chimeric human-mouse IgG antibodies with shuffled constant region exons demonstrate that multiple domains contribute to in vivo half-life. Cancer Res 58:3905-3908
    • (1998) Cancer Res , vol.58 , pp. 3905-3908
    • Zuckier, L.S.1    Chang, C.J.2    Scharff, M.D.3    Morrison, S.L.4
  • 17
  • 18
    • 0004378327 scopus 로고
    • Turnover of labeled normal gamma globulin in multiple myeloma
    • Lippincott SW, Korman S, Fong C, et al (1960) Turnover of labeled normal gamma globulin in multiple myeloma. J Clin Invest 39:565-572
    • (1960) J Clin Invest , vol.39 , pp. 565-572
    • Lippincott, S.W.1    Korman, S.2    Fong, C.3
  • 20
    • 0000146003 scopus 로고
    • A theoretical model of t-globulin catabolism
    • Brambell FWR, Hemmings WA, Morris IG (1964) A theoretical model of t-globulin catabolism. Nature 203: 1352-1355
    • (1964) Nature , vol.203 , pp. 1352-1355
    • Brambell, F.W.R.1    Hemmings, W.A.2    Morris, I.G.3
  • 21
    • 0029891262 scopus 로고    scopus 로고
    • The protection receptor for IgG catabolism is the b2-microglobulin- containing neonatal intestinal transport receptor
    • Junghans RP, Anderson CL (1996) The protection receptor for IgG catabolism is the b2-microglobulin-containing neonatal intestinal transport receptor. Proc Natl Acad Sci USA 93:5512-5516
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5512-5516
    • Junghans, R.P.1    Anderson, C.L.2
  • 22
    • 0029927482 scopus 로고    scopus 로고
    • Abnormally short serum half-lives of IgG in beta-2-microglobulin- deficient mice
    • Ghetie V, Hubbard JG, Kim TK, Tsen MF, Lee Y, Ward ES (1996) Abnormally short serum half-lives of IgG in beta-2-microglobulin-deficient mice. Eur J Immunol 26:690-696
    • (1996) Eur J Immunol , vol.26 , pp. 690-696
    • Ghetie, V.1    Hubbard, J.G.2    Kim, T.K.3    Tsen, M.F.4    Lee, Y.5    Ward, E.S.6
  • 23
    • 0029856774 scopus 로고    scopus 로고
    • Increased clearance of IgG in mice that lack b2-mi-croglobulin: Possible protective role of FcRn
    • Israel EJ, Wilsker DF, Hayes KC, Schoenfeld D, Simister NE (1996) Increased clearance of IgG in mice that lack b2-mi-croglobulin: possible protective role of FcRn. Immunology 89:573-578
    • (1996) Immunology , vol.89 , pp. 573-578
    • Israel, E.J.1    Wilsker, D.F.2    Hayes, K.C.3    Schoenfeld, D.4    Simister, N.E.5
  • 24
    • 0030993535 scopus 로고    scopus 로고
    • Finally: The Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG
    • Junghans RP (1997) Finally: The Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG. Immunol Res 16:29-57
    • (1997) Immunol Res , vol.16 , pp. 29-57
    • Junghans, R.P.1
  • 25
    • 0028170522 scopus 로고
    • Catabolism of the murine IgG1 molecule: Evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice
    • Kim JK, Tsen MF, Ghetie V, Ward ES (1994) Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice. Scand J Immunol 40:457-465
    • (1994) Scand J Immunol , vol.40 , pp. 457-465
    • Kim, J.K.1    Tsen, M.F.2    Ghetie, V.3    Ward, E.S.4
  • 26
    • 0028220297 scopus 로고
    • Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis
    • Kim J-K, Tsen M-F, Ghetie V, Ward ES (1994) Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis. Eur J Immunol 24:542-548
    • (1994) Eur J Immunol , vol.24 , pp. 542-548
    • Kim, J.-K.1    Tsen, M.-F.2    Ghetie, V.3    Ward, E.S.4
  • 27
    • 0025014962 scopus 로고
    • Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors
    • Jain RK (1990) Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors. Cancer Res (Suppl) 50:814s-819s
    • (1990) Cancer Res (Suppl) , vol.50
    • Jain, R.K.1
  • 28
    • 0025376171 scopus 로고
    • A modeling analysis of monoclonal antibody percolation through tumors: A binding-site barrier
    • Fujimori K, Covell DG, Fletcher JE, Weinstein JN (1990) A modeling analysis of monoclonal antibody percolation through tumors: a binding-site barrier. J Nucl Med 31: 1191-1198
    • (1990) J Nucl Med , vol.31 , pp. 1191-1198
    • Fujimori, K.1    Covell, D.G.2    Fletcher, J.E.3    Weinstein, J.N.4
  • 29
    • 0022946258 scopus 로고
    • In vitro and in vivo tumor models for studies of distribution of radiolabelled monoclonal antibodies and fragments
    • Buchegger F, Halpern SE, Sutherland RM, Schreyer M, Mach J-P (1986) In vitro and in vivo tumor models for studies of distribution of radiolabelled monoclonal antibodies and fragments. Nuklearmedizin 25:207-209
    • (1986) Nuklearmedizin , vol.25 , pp. 207-209
    • Buchegger, F.1    Halpern, S.E.2    Sutherland, R.M.3    Schreyer, M.4    Mach, J.-P.5
  • 30
    • 0020973474 scopus 로고
    • 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy
    • 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy. J Clin Invest 72:2101-2114
    • (1983) J Clin Invest , vol.72 , pp. 2101-2114
    • Larson, S.M.1    Carrasquillo, J.A.2    Krohn, K.A.3
  • 31
    • 0021042615 scopus 로고
    • On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice
    • Parham P (1983) On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice. J Immunol 131:2895-2902
    • (1983) J Immunol , vol.131 , pp. 2895-2902
    • Parham, P.1
  • 34
    • 0023144781 scopus 로고
    • Penetration and binding of radiolabeled anti-carci-noembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids
    • Sutherland R, Buchegger F, Schreyer M, Vacca A, Mach J-P (1987) Penetration and binding of radiolabeled anti-carci-noembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids. Cancer Res 47:1627-1633
    • (1987) Cancer Res , vol.47 , pp. 1627-1633
    • Sutherland, R.1    Buchegger, F.2    Schreyer, M.3    Vacca, A.4    MacH, J.-P.5
  • 35
    • 0023639244 scopus 로고
    • 2, and Fab' in mice after intravenous injection. Comparison between anti-B cell (an-ti-LyB8.2) and irrelevant (MOPC-21) antibodies
    • 2, and Fab' in mice after intravenous injection. Comparison between anti-B cell (an-ti-LyB8.2) and irrelevant (MOPC-21) antibodies. J Immunol 139:3041-3049
    • (1987) J Immunol , vol.139 , pp. 3041-3049
    • Holton, O.D.I.1    Black, C.D.V.2    Parker, R.J.3
  • 37
    • 0024833055 scopus 로고
    • Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
    • Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, et al (1989) Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 246:1275-1281
    • (1989) Science , vol.246 , pp. 1275-1281
    • Huse, W.D.1    Sastry, L.2    Iverson, S.A.3    Kang, A.S.4    Alting-Mees, M.5    Burton, D.R.6
  • 38
    • 0025910746 scopus 로고
    • Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces
    • Kang AS, Barbas CF, Janda KD, Benkovic SJ, Lerner RA (1991) Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proc Natl Acad Sci USA 88:4363-4366
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4363-4366
    • Kang, A.S.1    Barbas, C.F.2    Janda, K.D.3    Benkovic, S.J.4    Lerner, R.A.5
  • 39
    • 0004198722 scopus 로고
    • Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Esche-richia coli
    • Huston JS, Levinson D, Mudgett-Hunter M, Tai M-S, No-votny J, Margolies MN, et al (1988) Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Esche-richia coli. Proc Natl Acad Sci USA 85:5879-5883
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5879-5883
    • Huston, J.S.1    Levinson, D.2    Mudgett-Hunter, M.3    Tai, M.-S.4    No-Votny, J.5    Margolies, M.N.6
  • 41
    • 0026327378 scopus 로고
    • Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49
    • Milenic DE, Yokota T, Filpula DR, Finkelman MAJ, Dodd SW, Wood JF, et al (1991) Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res 51:6363-6371
    • (1991) Cancer Res , vol.51 , pp. 6363-6371
    • Milenic, D.E.1    Yokota, T.2    Filpula, D.R.3    Finkelman, M.A.J.4    Dodd, S.W.5    Wood, J.F.6
  • 42
    • 8944233018 scopus 로고
    • New approaches to improved antibody targeting
    • Schlom J (1991) New approaches to improved antibody targeting. Antibody Immunoconjug Radiopharm 4:819-828
    • (1991) Antibody Immunoconjug Radiopharm , vol.4 , pp. 819-828
    • Schlom, J.1
  • 44
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
    • Yokota T, Milenic DE, Whitlow M, Schlom J (1992) Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 52:3402-3408
    • (1992) Cancer Res , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Schlom, J.4
  • 45
    • 0024461313 scopus 로고
    • Binding activities of a repertoire of single immuno-globulin variable domains secreted from Escherichia coli
    • Ward ES, Gussow D, Griffiths AD, Jones PT, Winter G (1989) Binding activities of a repertoire of single immuno-globulin variable domains secreted from Escherichia coli. Nature 341:544-546
    • (1989) Nature , vol.341 , pp. 544-546
    • Ward, E.S.1    Gussow, D.2    Griffiths, A.D.3    Jones, P.T.4    Winter, G.5
  • 47
    • 0024496497 scopus 로고
    • A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen
    • Taub R, Gould RJ, Garsky VM, Cicarone TM, Hoxie J, Friedman PA, et al (1989) A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen. J Biol Chem 264:259-265
    • (1989) J Biol Chem , vol.264 , pp. 259-265
    • Taub, R.1    Gould, R.J.2    Garsky, V.M.3    Cicarone, T.M.4    Hoxie, J.5    Friedman, P.A.6
  • 48
    • 0025729547 scopus 로고
    • Design of bioactive peptides based on antibody hypervariable region structures: Development of conformationally constrained and dimeric peptides with enhanced affinity
    • Williams WV, Kieber-Emmons T, VonFeldt J, Greene MI, Weiner DB (1991) Design of bioactive peptides based on antibody hypervariable region structures: Development of conformationally constrained and dimeric peptides with enhanced affinity. J Biol Chem 266:5182-5190
    • (1991) J Biol Chem , vol.266 , pp. 5182-5190
    • Williams, W.V.1    Kieber-Emmons, T.2    Vonfeldt, J.3    Greene, M.I.4    Weiner, D.B.5
  • 49
    • 0028047805 scopus 로고
    • Thrombus imaging with technetium-99m synthetic peptides based upon the binding domain of a monoclonal antibody to activated platelets
    • Knight LC, Radcliffe R, Maurer AH, Rodwell JD, Alvarez VL (1994) Thrombus imaging with technetium-99m synthetic peptides based upon the binding domain of a monoclonal antibody to activated platelets. J Nucl Med 35:282-288
    • (1994) J Nucl Med , vol.35 , pp. 282-288
    • Knight, L.C.1    Radcliffe, R.2    Maurer, A.H.3    Rodwell, J.D.4    Alvarez, V.L.5
  • 50
    • 0031979136 scopus 로고    scopus 로고
    • Improving the tumor specificity and retention of antibody-based molecules
    • Adams GP (1998) Improving the tumor specificity and retention of antibody-based molecules. In Vivo 12:11-22
    • (1998) In Vivo , vol.12 , pp. 11-22
    • Adams, G.P.1
  • 51
    • 0031911476 scopus 로고    scopus 로고
    • Reducing the renal uptake of radiolabeled antibody fragments and pep-tides for diagnosis and therapy: Present status, future prospects and limitations
    • Behr TM, Goldenberg DM, Becker W (2005) Reducing the renal uptake of radiolabeled antibody fragments and pep-tides for diagnosis and therapy: present status, future prospects and limitations. Eur J Nucl Med 25:201-212
    • (2005) Eur J Nucl Med , vol.25 , pp. 201-212
    • Behr, T.M.1    Goldenberg, D.M.2    Becker, W.3
  • 53
    • 0015315530 scopus 로고
    • Antibody affinity-III. The role of multivalence
    • Hornick CL, Karush F (1972) Antibody affinity-III. The role of multivalence. Immunochemistry 9:325-340
    • (1972) Immunochemistry , vol.9 , pp. 325-340
    • Hornick, C.L.1    Karush, F.2
  • 54
    • 0015313012 scopus 로고
    • The influence of polyva-lency on the binding properties of antibodies
    • Crothers DM, Metzger H (1972) The influence of polyva-lency on the binding properties of antibodies. Immunochemistry 9:341-357
    • (1972) Immunochemistry , vol.9 , pp. 341-357
    • Crothers, D.M.1    Metzger, H.2
  • 55
    • 0026705890 scopus 로고
    • Effect of bivalent interaction upon apparent antibody affinity: Experimental confirmation of theory using fluorescence photobleaching and implications for antibody binding assays
    • Kaufman EN, Jain RK (1992) Effect of bivalent interaction upon apparent antibody affinity: experimental confirmation of theory using fluorescence photobleaching and implications for antibody binding assays. Cancer Res 52:4157-4167
    • (1992) Cancer Res , vol.52 , pp. 4157-4167
    • Kaufman, E.N.1    Jain, R.K.2
  • 56
    • 0034671357 scopus 로고    scopus 로고
    • Influence of affinity and antigen density on antibody localization in a modifiable tumor targeting model
    • Zuckier LS, Berkowitz EZ, Sattenberg RJ, Zhao QH, Deng HF, Scharff MD (2000) Influence of affinity and antigen density on antibody localization in a modifiable tumor targeting model. Cancer Res 60:7008-7013
    • (2000) Cancer Res , vol.60 , pp. 7008-7013
    • Zuckier, L.S.1    Berkowitz, E.Z.2    Sattenberg, R.J.3    Zhao, Q.H.4    Deng, H.F.5    Scharff, M.D.6
  • 57
    • 0025342215 scopus 로고
    • Light chain variants of an IgG3 anti-GD3 monoclonal antibody and the relationship among avidity, effector functions, tumor targeting, and antitumor activity
    • Chapman PB, Lonberg M, Houghton AN (1990) Light chain variants of an IgG3 anti-GD3 monoclonal antibody and the relationship among avidity, effector functions, tumor targeting, and antitumor activity. Cancer Res 50: 1503-1509
    • (1990) Cancer Res , vol.50 , pp. 1503-1509
    • Chapman, P.B.1    Lonberg, M.2    Houghton, A.N.3
  • 58
    • 0024121472 scopus 로고
    • Identification of mutant monoclonal antibodies with increased antigen binding
    • Pollock RR, French DL, Gefter ML, Scharff MD (1988) Identification of mutant monoclonal antibodies with increased antigen binding. Proc Natl Acad Sci USA 85: 2298-2302
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2298-2302
    • Pollock, R.R.1    French, D.L.2    Gefter, M.L.3    Scharff, M.D.4
  • 59
    • 0027572697 scopus 로고
    • Preparation, characterization, and in vivo biodistribution properties of synthetically cross-linked multivalent antitu-mor antibody fragments
    • Schott ME, Frazier KA, Pollack DK, Verbanac KM (1993) Preparation, characterization, and in vivo biodistribution properties of synthetically cross-linked multivalent antitu-mor antibody fragments. Bioconjugate Chem 4:153-165
    • (1993) Bioconjugate Chem , vol.4 , pp. 153-165
    • Schott, M.E.1    Frazier, K.A.2    Pollack, D.K.3    Verbanac, K.M.4
  • 61
    • 0030020157 scopus 로고    scopus 로고
    • Preparation of a trivalent antigen-binding construct using polyoxime chemistry: Improved bio-distribution and potential for therapeutic application
    • Werlen RC, Lankinen M, Offord RE, Schubiger PA, Smith A, Rose K (1996) Preparation of a trivalent antigen-binding construct using polyoxime chemistry: improved bio-distribution and potential for therapeutic application. Cancer Res 56:809-815
    • (1996) Cancer Res , vol.56 , pp. 809-815
    • Werlen, R.C.1    Lankinen, M.2    Offord, R.E.3    Schubiger, P.A.4    Smith, A.5    Rose, K.6
  • 62
    • 0027316301 scopus 로고
    • Monoclonal antibody homodimers: Enhanced antitumor activity in nude mice
    • Wolff EA, Schreiber GJ, Cosand WL, Raff HV (1993) Monoclonal antibody homodimers: enhanced antitumor activity in nude mice. Cancer Res 53:2560-2565
    • (1993) Cancer Res , vol.53 , pp. 2560-2565
    • Wolff, E.A.1    Schreiber, G.J.2    Cosand, W.L.3    Raff, H.V.4
  • 63
    • 0028239141 scopus 로고
    • Recombinant polymeric IgG: An approach to engineering more potent antibodies
    • Smith RIF, Morrison SL (1994) Recombinant polymeric IgG: an approach to engineering more potent antibodies. Bio/Technology 12:683-688
    • (1994) Bio/Technology , vol.12 , pp. 683-688
    • Smith, R.I.F.1    Morrison, S.L.2
  • 64
    • 0028902638 scopus 로고
    • Structure and function of several anti-dansyl chimeric antibodies formed by domain interchanges between human IgM and mouse IgG2b
    • Poon PH, Morrison SL, Schumaker VN (1995) Structure and function of several anti-dansyl chimeric antibodies formed by domain interchanges between human IgM and mouse IgG2b. J Biol Chem 270:8571-8577
    • (1995) J Biol Chem , vol.270 , pp. 8571-8577
    • Poon, P.H.1    Morrison, S.L.2    Schumaker, V.N.3
  • 65
    • 0027197493 scopus 로고
    • "Diabodies": Small bivalent and bispecific antibody fragments
    • Holliger P, Prospero T, Winter G (1993) "Diabodies": small bivalent and bispecific antibody fragments. Proc Natl Acad Sci USA 90:6444-6448
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6444-6448
    • Holliger, P.1    Prospero, T.2    Winter, G.3
  • 66
    • 0027303686 scopus 로고
    • Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 Anti-c-erbB-2 single-chain Fv
    • Adams GP, McCartney JE, Tai M-S, Oppermann H, Huston JS, Stafford WF III, et al (1993) Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 Anti-c-erbB-2 single-chain Fv. Cancer Res 53:4026-4034
    • (1993) Cancer Res , vol.53 , pp. 4026-4034
    • Adams, G.P.1    McCartney, J.E.2    Tai, M.-S.3    Oppermann, H.4    Huston, J.S.5    Stafford III, W.F.6
  • 68
    • 13144295210 scopus 로고    scopus 로고
    • Tumor targeting properties of anti-C-ERB-2 single-chain Fv molecules over a wide range of affinities for the same epitope
    • Adams GP, Schier R, McCall AM, Wolf EJ, Marks JD, Wei-ner LM (1996) Tumor targeting properties of anti-C-ERB-2 single-chain Fv molecules over a wide range of affinities for the same epitope. Tumor Targeting 2:154
    • (1996) Tumor Targeting , vol.2 , pp. 154
    • Adams, G.P.1    Schier, R.2    McCall, A.M.3    Wolf, E.J.4    Marks, J.D.5    Wei-Ner, L.M.6
  • 69
    • 0031456776 scopus 로고    scopus 로고
    • Experimental tumor targeting with radiolabeled ligands
    • Buchsbaum DJ (1997) Experimental tumor targeting with radiolabeled ligands. Cancer (Suppl) 80:2371-2377
    • (1997) Cancer (Suppl) , vol.80 , pp. 2371-2377
    • Buchsbaum, D.J.1
  • 70
    • 7844237897 scopus 로고    scopus 로고
    • Novel clinical approaches in monoclonal antibody-based management in colorectal cancer patients: Radioimmunoguided surgery and antigen augmentation
    • Roselli M, Buonomo O, Piazza A, Guadagni F, Vecchione A, Brunetti E, et al (1998) Novel clinical approaches in monoclonal antibody-based management in colorectal cancer patients: radioimmunoguided surgery and antigen augmentation. Semin Surg Oncol 15:254-262
    • (1998) Semin Surg Oncol , vol.15 , pp. 254-262
    • Roselli, M.1    Buonomo, O.2    Piazza, A.3    Guadagni, F.4    Vecchione, A.5    Brunetti, E.6
  • 71
    • 0024448665 scopus 로고
    • Quo vadis ra-dioimmune imaging (editorial)
    • Fischman AJ, Khaw BA, Strauss HW (1989) Quo vadis ra-dioimmune imaging (editorial). J Nucl Med 30:1911-1915
    • (1989) J Nucl Med , vol.30 , pp. 1911-1915
    • Fischman, A.J.1    Khaw, B.A.2    Strauss, H.W.3
  • 72
    • 0026501317 scopus 로고
    • Predicted and observed effects of antibody affinity and antigen density on monoclonal antibody uptake in solid tumors
    • Sung C, Shockley TR, Morrison PF, Dvorak HF, Yarmush ML, Dedrick RL (1992) Predicted and observed effects of antibody affinity and antigen density on monoclonal antibody uptake in solid tumors. Cancer Res 52:377-384
    • (1992) Cancer Res , vol.52 , pp. 377-384
    • Sung, C.1    Shockley, T.R.2    Morrison, P.F.3    Dvorak, H.F.4    Yarmush, M.L.5    Dedrick, R.L.6
  • 73
    • 0024819245 scopus 로고
    • Influence of animal host and tumor implantation site on radio-antibody uptake in the GW-39 human colonic cancer xenograft
    • Blumenthal RD, Sharkey RM, Kashi R, Natale AM, Goldenberg DM (1989) Influence of animal host and tumor implantation site on radio-antibody uptake in the GW-39 human colonic cancer xenograft. Int J Cancer 44:1041-1047
    • (1989) Int J Cancer , vol.44 , pp. 1041-1047
    • Blumenthal, R.D.1    Sharkey, R.M.2    Kashi, R.3    Natale, A.M.4    Goldenberg, D.M.5
  • 74
    • 0026560608 scopus 로고
    • Improving the antigen affinity of an antibody Fv-fragment by protein design
    • Riechmann L, Weill M, Cavanagh J (1992) Improving the antigen affinity of an antibody Fv-fragment by protein design. J Mol Biol 224:913-918
    • (1992) J Mol Biol , vol.224 , pp. 913-918
    • Riechmann, L.1    Weill, M.2    Cavanagh, J.3
  • 75
    • 0022555989 scopus 로고
    • Bispecific monoclonal antibodies from hybrid hybridomas
    • Suresh MR, Cuello AC, Milstein C (1986) Bispecific monoclonal antibodies from hybrid hybridomas. Methods En-zymol 121:210-228
    • (1986) Methods En-zymol , vol.121 , pp. 210-228
    • Suresh, M.R.1    Cuello, A.C.2    Milstein, C.3
  • 77
    • 0025180556 scopus 로고
    • Expression and characterization of a chimeric bi-functional antibody with therapeutic applications
    • Phelps JL, Beidler DE, Jue RA, Unger BW, Johnson MJ (1990) Expression and characterization of a chimeric bi-functional antibody with therapeutic applications. J Immunol 145:1200-1204
    • (1990) J Immunol , vol.145 , pp. 1200-1204
    • Phelps, J.L.1    Beidler, D.E.2    Jue, R.A.3    Unger, B.W.4    Johnson, M.J.5
  • 79
    • 0026333403 scopus 로고
    • Bifunctional antibody: A binary radiopharmaceutical delivery system for imaging co-lorectal carcinoma
    • Stickney DR, Anderson LD, Slater JB, Ahlem CN, Kirk GA, Schweighardt SA, et al (1991) Bifunctional antibody: a binary radiopharmaceutical delivery system for imaging co-lorectal carcinoma. Cancer Res 51:6650-6655
    • (1991) Cancer Res , vol.51 , pp. 6650-6655
    • Stickney, D.R.1    Anderson, L.D.2    Slater, J.B.3    Ahlem, C.N.4    Kirk, G.A.5    Schweighardt, S.A.6
  • 80
    • 0027428816 scopus 로고
    • Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: Pharmacoki-netics, biodistribution, scintigraphy and immune response
    • LeDoussal J-M, ChetanneauA, Gruaz-GuyonA, MartinM, Gautherot E, Lehur P-A, et al (1993) Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacoki-netics, biodistribution, scintigraphy and immune response. J Nucl Med 34:1662-1671
    • (1993) J Nucl Med , vol.34 , pp. 1662-1671
    • Ledoussal, J.-M.1    Gruaz-Guyona, C.2    Martinm Gautherot, E.3    Lehur, P.-A.4
  • 81
    • 0027166186 scopus 로고
    • Radioimmunodetection of medullary thyroid cancer using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer
    • Peltier P, Curtet C, Chatal J-F, LeDoussal J-M, Daniel G, Aillet G, et al (1993) Radioimmunodetection of medullary thyroid cancer using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer. J Nucl Med 34:1267-1273
    • (1993) J Nucl Med , vol.34 , pp. 1267-1273
    • Peltier, P.1    Curtet, C.2    Chatal, J.-F.3    Ledoussal, J.-M.4    Daniel, G.5    Aillet, G.6
  • 82
    • 30744455270 scopus 로고    scopus 로고
    • Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody
    • Sharkey RM, Cardillo TM, Rossi EA, Chang CH, Karacay H, McBride WJ, et al (2005) Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody. Nat Med 11:1250-1255
    • (2005) Nat Med , vol.11 , pp. 1250-1255
    • Sharkey, R.M.1    Cardillo, T.M.2    Rossi, E.A.3    Chang, C.H.4    Karacay, H.5    McBride, W.J.6
  • 83
    • 0025877853 scopus 로고
    • Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab') with specificity for carcinomas and human IL-2
    • Fell HP, Gayle MA, Grosmaire L, Ledbetter JA (1991) Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab') with specificity for carcinomas and human IL-2. J Immun 146:2446-2452
    • (1991) J Immun , vol.146 , pp. 2446-2452
    • Fell, H.P.1    Gayle, M.A.2    Grosmaire, L.3    Ledbetter, J.A.4
  • 84
    • 0025003251 scopus 로고
    • Expression and characterization of an antibody binding specificity joined to insulinlike growth factor 1: Potential applications for cellular targeting
    • Shin S-U, Morrison SL (1990) Expression and characterization of an antibody binding specificity joined to insulinlike growth factor 1: potential applications for cellular targeting. Proc Natl Acad Sci USA 87:5322-5326
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5322-5326
    • Shin, S.-U.1    Morrison, S.L.2
  • 86
    • 85078983931 scopus 로고
    • Clinical application of the avidin-biotin system for tumor targeting
    • Goldenberg DM (ed), CRC Press, Boca Raton
    • Paganelli G, Magnani P, Siccardi AG, Fazio F (1995) Clinical application of the avidin-biotin system for tumor targeting. In: Goldenberg DM (ed) Cancer therapy with ra-diolabeled antibodies. CRC Press, Boca Raton, pp 239-254
    • (1995) Cancer Therapy with Ra-diolabeled Antibodies , pp. 239-254
    • Paganelli, G.1    Magnani, P.2    Siccardi, A.G.3    Fazio, F.4
  • 87
    • 0026101150 scopus 로고
    • Monoclonal antibody pretargetting techniques for tumour localization: The avidin-biotin system
    • Paganelli G, Malcovati M, Fazio F (1991) Monoclonal antibody pretargetting techniques for tumour localization: the avidin-biotin system. Nucl Med Commun 12:211-234
    • (1991) Nucl Med Commun , vol.12 , pp. 211-234
    • Paganelli, G.1    Malcovati, M.2    Fazio, F.3
  • 88
    • 0025148991 scopus 로고
    • Imaging of tumor in patients with indium-111-labeled biotin and streptavidin-conjugated antibodies: Preliminary communication
    • Kalofonos HP, Rusckowski M, Siebecker DA, Sivolapenko GB, Snook D, Lavender JP, et al (1990) Imaging of tumor in patients with indium-111-labeled biotin and streptavidin-conjugated antibodies: preliminary communication. J Nucl Med 31:1791-1796
    • (1990) J Nucl Med , vol.31 , pp. 1791-1796
    • Kalofonos, H.P.1    Rusckowski, M.2    Siebecker, D.A.3    Sivolapenko, G.B.4    Snook, D.5    Lavender, J.P.6
  • 89
    • 0023619395 scopus 로고
    • Investigations of avidin and biotin for imaging applications
    • Hnatowich DJ, Virzi F, Rusckowski M (1987) Investigations of avidin and biotin for imaging applications. J Nucl Med 28:1294-1302
    • (1987) J Nucl Med , vol.28 , pp. 1294-1302
    • Hnatowich, D.J.1    Virzi, F.2    Rusckowski, M.3
  • 91
    • 0028032154 scopus 로고
    • Potential for re-combinant immunoglobulin constructs in the management of carcinoma
    • Hand PH, Kashmiri SVS, Schlom J (1994) Potential for re-combinant immunoglobulin constructs in the management of carcinoma. Cancer (Suppl) 73:1105-1113
    • (1994) Cancer (Suppl) , vol.73 , pp. 1105-1113
    • Hand, P.H.1    Kashmiri, S.V.S.2    Schlom, J.3
  • 92
    • 0023194592 scopus 로고
    • Human monoclonal antibody production: Current status and future prospects
    • James K, Bell GT (1987) Human monoclonal antibody production: Current status and future prospects. J Immunol Methods 100:5-40
    • (1987) J Immunol Methods , vol.100 , pp. 5-40
    • James, K.1    Bell, G.T.2
  • 93
    • 0025444252 scopus 로고
    • Human monoclonal antibodies and engineered antibodies in the management of cancer
    • James K (1990) Human monoclonal antibodies and engineered antibodies in the management of cancer. Semin Cancer Biol 1:243-253
    • (1990) Semin Cancer Biol , vol.1 , pp. 243-253
    • James, K.1
  • 94
    • 0017692919 scopus 로고
    • EB virus-induced B lymphocytic cell lines producing specific antibody
    • Steinitz M, Klein G, Koskimies S, Markel O (1977) EB virus-induced B lymphocytic cell lines producing specific antibody. Nature 269:420-422
    • (1977) Nature , vol.269 , pp. 420-422
    • Steinitz, M.1    Klein, G.2    Koskimies, S.3    Markel, O.4
  • 95
    • 0024238607 scopus 로고
    • Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus
    • Nakamura M, Burastero SE, Ueki Y, Larrick JW, Notkins AL, Casali P (1988) Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus. J Immun 141:4165-4172
    • (1988) J Immun , vol.141 , pp. 4165-4172
    • Nakamura, M.1    Burastero, S.E.2    Ueki, Y.3    Larrick, J.W.4    Notkins, A.L.5    Casali, P.6
  • 96
    • 0020401468 scopus 로고
    • Human hybrid-omas constructed with antigen-specific Epstein-Barr virus-transformed cell lines
    • Kozbor D, Lagarde AE, Roder JC (1982) Human hybrid-omas constructed with antigen-specific Epstein-Barr virus-transformed cell lines. Proc Natl Acad Sci USA 79:6651-6655
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 6651-6655
    • Kozbor, D.1    Lagarde, A.E.2    Roder, J.C.3
  • 97
    • 0021070137 scopus 로고
    • Human X (mouse X human) hybridomas stably producing human antibodies
    • Ostberg L, Pursch E (1983) Human X (mouse X human) hybridomas stably producing human antibodies. Hybridoma 2:361-367
    • (1983) Hybridoma , vol.2 , pp. 361-367
    • Ostberg, L.1    Pursch, E.2
  • 99
    • 0021716682 scopus 로고
    • Chimeric human antibody molecules: Mouse antigen-binding domains with human constant region domains
    • Morrison SL, Johnson MJ, Herzenberg LA, Oi VT (1984) Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. Proc Natl Acad Sci USA 81:6851-6855
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6851-6855
    • Morrison, S.L.1    Johnson, M.J.2    Herzenberg, L.A.3    Oi, V.T.4
  • 100
    • 0021802935 scopus 로고
    • Generations of human monoclonal antibodies reactive with cellular antigens
    • Morrison SL (1985) Generations of human monoclonal antibodies reactive with cellular antigens. Science 229: 1202-1207
    • (1985) Science , vol.229 , pp. 1202-1207
    • Morrison, S.L.1
  • 101
    • 0023621441 scopus 로고
    • Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies
    • Bruggemann M, Williams GT, Bindon CI, Clark MR, Walker MR, Jefferis R, et al (1987) Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. J Exp Med 166:1351-1361
    • (1987) J Exp Med , vol.166 , pp. 1351-1361
    • Bruggemann, M.1    Williams, G.T.2    Bindon, C.I.3    Clark, M.R.4    Walker, M.R.5    Jefferis, R.6
  • 103
    • 0022558297 scopus 로고
    • Replacing the complementarity-determining regions in a human antibody with those from a mouse
    • Jones PT, Dear PH, Foote J, Neuberger MS, Winter G (1986) Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 321:522-525
    • (1986) Nature , vol.321 , pp. 522-525
    • Jones, P.T.1    Dear, P.H.2    Foote, J.3    Neuberger, M.S.4    Winter, G.5
  • 105
    • 0025978976 scopus 로고
    • Man-made antibodies
    • Winter G, Milstein C (1991) Man-made antibodies. Nature 349:293-299
    • (1991) Nature , vol.349 , pp. 293-299
    • Winter, G.1    Milstein, C.2
  • 106
    • 0027078548 scopus 로고
    • Genetically engineered antibodies: Progress and prospects
    • Wright A, Shin S-U, Morrison SL (1992) Genetically engineered antibodies: progress and prospects. Crit Rev Immunol 12:125-168
    • (1992) Crit Rev Immunol , vol.12 , pp. 125-168
    • Wright, A.1    Shin, S.-U.2    Morrison, S.L.3
  • 107
    • 0023920595 scopus 로고
    • Reshaping human antibodies: Grafting an antilysozyme activity
    • Verhoeyen M, Milstein C, Winter G (1988) Reshaping human antibodies: grafting an antilysozyme activity. Science 239:1534-1536
    • (1988) Science , vol.239 , pp. 1534-1536
    • Verhoeyen, M.1    Milstein, C.2    Winter, G.3
  • 109
    • 0023197907 scopus 로고
    • Generation of an antibody with enhanced affinity and specificity for its antigen by protein engineering
    • Roberts S, Cheetham JC, Rees AR (1987) Generation of an antibody with enhanced affinity and specificity for its antigen by protein engineering. Nature 328:731-734
    • (1987) Nature , vol.328 , pp. 731-734
    • Roberts, S.1    Cheetham, J.C.2    Rees, A.R.3
  • 110
    • 0026418194 scopus 로고
    • Humanized antibodies for therapy
    • Co MS, Queen C (1991) Humanized antibodies for therapy. Nature 351:501-502
    • (1991) Nature , vol.351 , pp. 501-502
    • Co, M.S.1    Queen, C.2
  • 111
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • Mosier DE, Gulizia RJ, Baird SM, Wilson DB (1988) Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 335:256-259
    • (1988) Nature , vol.335 , pp. 256-259
    • Mosier, D.E.1    Gulizia, R.J.2    Baird, S.M.3    Wilson, D.B.4
  • 112
    • 0023753744 scopus 로고
    • The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
    • McCune JM, Namikawa R, Kaneshima H, et al (1988) The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 241:1632-1639
    • (1988) Science , vol.241 , pp. 1632-1639
    • McCune, J.M.1    Namikawa, R.2    Kaneshima, H.3
  • 113
    • 0030221606 scopus 로고    scopus 로고
    • Strategies for expressing human antibody repertoires in transgenic mice
    • Bruggemann M, Neuberger MS (1996) Strategies for expressing human antibody repertoires in transgenic mice. Immunol Today 17:391-397
    • (1996) Immunol Today , vol.17 , pp. 391-397
    • Bruggemann, M.1    Neuberger, M.S.2
  • 114
    • 0013553762 scopus 로고
    • Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: Construction of a heavy chain variable region-specific cDNA library
    • Sastry L, Alting-Mees M, Huse WD, Short JM, Sorge JA, Hay BN, et al (1989) Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: Construction of a heavy chain variable region-specific cDNA library. Proc Natl Acad Sci USA 86:5728-5732
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5728-5732
    • Sastry, L.1    Alting-Mees, M.2    Huse, W.D.3    Short, J.M.4    Sorge, J.A.5    Hay, B.N.6
  • 115
    • 0026905448 scopus 로고
    • Rapid evolution of peptide and protein binding properties in vitro
    • Wells JA, Lowman HB (1992) Rapid evolution of peptide and protein binding properties in vitro. Curr Opin Biotechnol 3:355-362
    • (1992) Curr Opin Biotechnol , vol.3 , pp. 355-362
    • Wells, J.A.1    Lowman, H.B.2
  • 117
    • 0032006660 scopus 로고    scopus 로고
    • Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies
    • Adams GP, Schier R, Marshall K, Wolf EJ, McCall AM, Marks JD, et al (1998) Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies. Cancer Res 58:485-490
    • (1998) Cancer Res , vol.58 , pp. 485-490
    • Adams, G.P.1    Schier, R.2    Marshall, K.3    Wolf, E.J.4    McCall, A.M.5    Marks, J.D.6
  • 119
    • 0025373376 scopus 로고
    • Murine monoclonal antibodies against carcinoembryonic antigen: Immunologi-cal, pharmacokinetic, and targeting properties in humans
    • Sharkey RM, Goldenberg DM, Goldenberg H, Lee RE, Ballance C, Pawlyk D, et al (1990) Murine monoclonal antibodies against carcinoembryonic antigen: immunologi-cal, pharmacokinetic, and targeting properties in humans. Cancer Res 50:2823-2831
    • (1990) Cancer Res , vol.50 , pp. 2823-2831
    • Sharkey, R.M.1    Goldenberg, D.M.2    Goldenberg, H.3    Lee, R.E.4    Ballance, C.5    Pawlyk, D.6
  • 120
    • 0026648277 scopus 로고
    • Radioimmunodetec-tion in cancer identification
    • Goldenberg DM, Larson SM (1992) Radioimmunodetec-tion in cancer identification. J Nucl Med 33:803-814
    • (1992) J Nucl Med , vol.33 , pp. 803-814
    • Goldenberg, D.M.1    Larson, S.M.2
  • 123
    • 0026739369 scopus 로고
    • Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for a binding site barrier
    • Juweid M, Neumann R, Paik C, Perez-Bacete MJ, Sato J, van Osdol W, et al (1992) Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Res 52:5144-5153
    • (1992) Cancer Res , vol.52 , pp. 5144-5153
    • Juweid, M.1    Neumann, R.2    Paik, C.3    Perez-Bacete, M.J.4    Sato, J.5    Van Osdol, W.6
  • 124
    • 0023904792 scopus 로고
    • The intraperitoneal delivery of radiola-beled monoclonal antibodies: Studies on the regional delivery advantage
    • Wahl RL, Barrett J, Geatti O, Liebert M, Wilson BS, Fisher S, et al (1988) The intraperitoneal delivery of radiola-beled monoclonal antibodies: studies on the regional delivery advantage. Cancer Immunol Immunother 26:187-201
    • (1988) Cancer Immunol Immunother , vol.26 , pp. 187-201
    • Wahl, R.L.1    Barrett, J.2    Geatti, O.3    Liebert, M.4    Wilson, B.S.5    Fisher, S.6
  • 125
    • 0023516782 scopus 로고
    • Antibody-guided irradiation of advanced ovarian cancer with in-traperitoneally administered radiolabeled monoclonal antibodies
    • Epentos AA, Munro AJ, Stewart S, et al (1987) Antibody-guided irradiation of advanced ovarian cancer with in-traperitoneally administered radiolabeled monoclonal antibodies. J Clin Oncol 5:1890-1899
    • (1987) J Clin Oncol , vol.5 , pp. 1890-1899
    • Epentos, A.A.1    Munro, A.J.2    Stewart, S.3
  • 126
    • 0023605742 scopus 로고
    • 111 In-labeled T101 monoclonal antibody in patients with cutaneous T-cell lymphoma
    • 111 In-labeled T101 monoclonal antibody in patients with cutaneous T-cell lymphoma. Cancer Res 47:6093-6099
    • (1987) Cancer Res , vol.47 , pp. 6093-6099
    • Keenan, A.M.1    Weinstein, J.N.2    Carrasquillo, J.A.3
  • 127
    • 0036498790 scopus 로고    scopus 로고
    • Phase II trial of murine 131I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
    • Reardon DA, Akabani G, Coleman RE, Friedman AH, Friedman HS, Herndon II JE, et al (2005) Phase II trial of murine 131I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol 20:1389-1397
    • (2005) J Clin Oncol , vol.20 , pp. 1389-1397
    • Reardon, D.A.1    Akabani, G.2    Coleman, R.E.3    Friedman, A.H.4    Friedman, H.S.5    Herndon, I.I.J.E.6
  • 129
    • 0025733498 scopus 로고
    • Enhanced tumor uptake of macromolecules induced by a novel vasoactive interleu-kin 2 immunoconjugate
    • LeBerthon B, Khawli LA, Alauddin M, Miller GK, Charak BS, Mazumder A, et al (1991) Enhanced tumor uptake of macromolecules induced by a novel vasoactive interleu-kin 2 immunoconjugate. Cancer Res 51:2694-2698
    • (1991) Cancer Res , vol.51 , pp. 2694-2698
    • Leberthon, B.1    Khawli, L.A.2    Alauddin, M.3    Miller, G.K.4    Charak, B.S.5    Mazumder, A.6
  • 130
    • 0028074468 scopus 로고
    • Radioimmunotherapy with monoclonal antibodies: A new horizon in nuclear medicine therapy
    • Sautter-Bihl ML (1994) Radioimmunotherapy with monoclonal antibodies: A new horizon in nuclear medicine therapy. Nucklearmedizin 33:167-173
    • (1994) Nucklearmedizin , vol.33 , pp. 167-173
    • Sautter-Bihl, M.L.1
  • 132
    • 84889822279 scopus 로고    scopus 로고
    • Monoclonal antibodies in oncology
    • Aktolun C, Tauxe WN (eds), Springer, Berlin
    • Zuckier LS (1999) Monoclonal antibodies in oncology. In: Aktolun C, Tauxe WN (eds) Nuclear oncology. Springer, Berlin, pp 359-369
    • (1999) Nuclear Oncology , pp. 359-369
    • Zuckier, L.S.1


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