메뉴 건너뛰기




Volumn 41, Issue 5, 2012, Pages 1643-1652

Clinical significance of LGR5 and CD44 expression in locally advanced rectal cancer after preoperative chemoradiotherapy

Author keywords

CD44; Chemoradiotherapy; Disease recurrence; LGR5; Poor prognosis; Rectal cancer

Indexed keywords

FLUOROURACIL; HERMES ANTIGEN; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; PROTEIN; UFT; UNCLASSIFIED DRUG;

EID: 84867777294     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1598     Document Type: Article
Times cited : (28)

References (37)
  • 1
    • 6044226542 scopus 로고    scopus 로고
    • Preoperative versus postoperative chemoradiotherapy for rectal cancer
    • Sauer R, Becker H, Hohenberger W, et al: Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351: 1731-1740, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 1731-1740
    • Sauer, R.1    Becker, H.2    Hohenberger, W.3
  • 2
    • 61349188341 scopus 로고    scopus 로고
    • Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): A multicentre, randomised trial
    • Sebag-Montefiore D, Stephens RJ, Steele R, et al: Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet 373: 811-820, 2009.
    • (2009) Lancet , vol.373 , pp. 811-820
    • Sebag-Montefiore, D.1    Stephens, R.J.2    Steele, R.3
  • 6
    • 56749091913 scopus 로고    scopus 로고
    • Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue
    • Becker L, Huang Q and Mashimo H: Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue. Sci World J 8: 1168-1176, 2008.
    • (2008) Sci World J , vol.8 , pp. 1168-1176
    • Becker, L.1    Huang, Q.2    Mashimo, H.3
  • 7
    • 62549118631 scopus 로고    scopus 로고
    • Wnt signaling, lgr5, and stem cells in the intestine and skin
    • Haegebarth A and Clevers H: Wnt signaling, lgr5, and stem cells in the intestine and skin. Am J Pathol 174: 715-721, 2009.
    • (2009) Am J Pathol , vol.174 , pp. 715-721
    • Haegebarth, A.1    Clevers, H.2
  • 8
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • Sato T, Vries RG, Snippert HJ, et al: Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459: 262-265, 2009.
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1    Vries, R.G.2    Snippert, H.J.3
  • 9
    • 59049106578 scopus 로고    scopus 로고
    • Crypt stem cells as the cells-of-origin of intestinal cancer
    • Barker N, Ridgway RA, van Es JH, et al: Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457: 608-611, 2009.
    • (2009) Nature , vol.457 , pp. 608-611
    • Barker, N.1    Ridgway, R.A.2    Van Es, J.H.3
  • 10
    • 77954652500 scopus 로고    scopus 로고
    • Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer
    • Uchida H, Yamazaki K, Fukuma M, et al: Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer. Cancer Sci 101: 1731-1737, 2010.
    • (2010) Cancer Sci , vol.101 , pp. 1731-1737
    • Uchida, H.1    Yamazaki, K.2    Fukuma, M.3
  • 12
    • 11844256383 scopus 로고    scopus 로고
    • Mechanism and biological significance of CD44 cleavage
    • DOI 10.1111/j.1349-7006.2004.tb03179.x
    • Nagano O and Saya H: Mechanism and biological significance of CD44 cleavage. Cancer Sci 95: 930-935, 2004. (Pubitemid 40089583)
    • (2004) Cancer Science , vol.95 , Issue.12 , pp. 930-935
    • Nagano, O.1    Saya, H.2
  • 13
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • Reya T, Morrison SJ, Clarke MF, et al: Stem cells, cancer, and cancer stem cells. Nature 414: 105-111, 2001. (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 16
    • 16544366235 scopus 로고    scopus 로고
    • CD44 in cancer progression: Adhesion, migration and growth regulation
    • DOI 10.1023/B:HIJO.0000032354.94213.69
    • Marhaba R and Zoller M: CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol 35: 211-231, 2004. (Pubitemid 40585308)
    • (2004) Journal of Molecular Histology , vol.35 , Issue.3 , pp. 211-231
    • Marhaba, R.1    Zoller, M.2
  • 17
  • 18
    • 0037277035 scopus 로고    scopus 로고
    • CD44 and its partners in metastasis
    • Jothy S: CD44 and its partners in metastasis. Clin Exp Metastasis 20: 195-201, 2003.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 195-201
    • Jothy, S.1
  • 23
    • 34547525409 scopus 로고    scopus 로고
    • Phases of Canonical Wnt Signaling During the Development of Mouse Intestinal Epithelium
    • DOI 10.1053/j.gastro.2007.04.072, PII S0016508507009304
    • Kim BM, Mao J, Taketo MM, et al: Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology 133: 529-538, 2007. (Pubitemid 47187338)
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 529-538
    • Kim, B.1    Mao, J.2    Taketo, M.M.3    Shivdasani, R.A.4
  • 24
    • 0035110959 scopus 로고    scopus 로고
    • Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: A novel target mechanism concept for pharmacokinetic modulating chemotherapy
    • Yoshikawa R, Kusunoki M, Yanagi H, et al: Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. Cancer Res 61: 1029-1037, 2001. (Pubitemid 32174421)
    • (2001) Cancer Research , vol.61 , Issue.3 , pp. 1029-1037
    • Yoshikawa, R.1    Kusunoki, M.2    Yanagi, H.3    Noda, M.4    Furuyama, J.-I.5    Yamamura, T.6    Hashimoto-Tamaoki, T.7
  • 25
    • 0024358259 scopus 로고
    • The linear-quadratic formula and progress in fractionated radiotherapy
    • Fowler JF: The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 62: 679-694, 1989.
    • (1989) Br J Radiol , vol.62 , pp. 679-694
    • Fowler, J.F.1
  • 26
    • 79959329138 scopus 로고    scopus 로고
    • Evaluation of biologic effective dose and schedule of fractionation for preoperative radiotherapy for rectal cancer: Meta-analyses and meta-regression
    • Viani GA, Stefano EJ, Soares FV, et al: Evaluation of biologic effective dose and schedule of fractionation for preoperative radiotherapy for rectal cancer: meta-analyses and meta-regression. Int J Radiat Oncol Biol Phys 80: 985-991, 2011.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 985-991
    • Viani, G.A.1    Stefano, E.J.2    Soares, F.V.3
  • 29
    • 71549155909 scopus 로고    scopus 로고
    • Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy
    • Saigusa S, Tanaka K, Toiyama Y, et al: Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. Ann Surg Oncol 16: 3488-3498, 2009.
    • (2009) Ann Surg Oncol , vol.16 , pp. 3488-3498
    • Saigusa, S.1    Tanaka, K.2    Toiyama, Y.3
  • 30
    • 0035136377 scopus 로고    scopus 로고
    • Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: Utility in the diagnosis of mantle cell lymphoma
    • Bijwaard KE, Aguilera NS, Monczak Y, et al: Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma. Clin Chem 47: 195-201, 2001. (Pubitemid 32142916)
    • (2001) Clinical Chemistry , vol.47 , Issue.2 , pp. 195-201
    • Bijwaard, K.E.1    Aguilera, N.S.I.2    Monczak, Y.3    Trudel, M.4    Taubenberger, J.K.5    Lichy, J.H.6
  • 31
    • 57849123270 scopus 로고    scopus 로고
    • Chemoradiotherapy and adjuvant chemotherapy for rectal cancer
    • Watanabe T: Chemoradiotherapy and adjuvant chemotherapy for rectal cancer. Int J Clin Oncol 13: 488-497, 2008.
    • (2008) Int J Clin Oncol , vol.13 , pp. 488-497
    • Watanabe, T.1
  • 33
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • DOI 10.1038/nature03319
    • Reya T and Clevers H: Wnt signalling in stem cells and cancer. Nature 434: 843-850, 2005. (Pubitemid 40558990)
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 34
    • 77955222623 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres
    • Kanwar SS, Yu Y, Nautiyal J, et al: The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres. Mol Cancer 9: 212, 2010.
    • (2010) Mol Cancer , vol.9 , pp. 212
    • Kanwar, S.S.1    Yu, Y.2    Nautiyal, J.3
  • 35
    • 79955800644 scopus 로고    scopus 로고
    • Significance of Lgr5(+ve) cancer stem cells in the colon and rectum
    • Takahashi H, Ishii H, Nishida N, et al: Significance of Lgr5(+ve) cancer stem cells in the colon and rectum. Ann Surg Oncol 18: 1166-1174, 2011.
    • (2011) Ann Surg Oncol , vol.18 , pp. 1166-1174
    • Takahashi, H.1    Ishii, H.2    Nishida, N.3
  • 36
    • 0033964912 scopus 로고    scopus 로고
    • CD44S expression in human colon carcinomas influences growth of liver metastases
    • DOI 10.1002/(SICI)1097-0215(20000215)85:4<523::AID-IJC13>3.0.CO;2-6
    • Choi SH, Takahashi K, Eto H, et al: CD44s expression in human colon carcinomas influences growth of liver metastases. Int J Cancer 85: 523-526, 2000. (Pubitemid 30075131)
    • (2000) International Journal of Cancer , vol.85 , Issue.4 , pp. 523-526
    • Choi, S.H.1    Takahashi, K.2    Hiroshi, E.3    Yoon, S.S.4    Tanabe, K.K.5
  • 37
    • 0028891469 scopus 로고
    • Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis
    • Mulder JW, Wielenga VJ, Polak MM, et al: Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis. Gut 36: 76-80, 1995.
    • (1995) Gut , vol.36 , pp. 76-80
    • Mulder, J.W.1    Wielenga, V.J.2    Polak, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.