The influence of ETA and ETB receptor blockers on LPS-induced oxidative stress and NF-κB signaling pathway in heart

General Physiology and Biophysics

Volumn 31, Issue 3, 2012, Pages 271-278

  Piechota Polanczyk, Aleksandra ^a   Kleniewska, Paulina ^a   Goraca, Anna ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Endothelin 1 receptors; Heart; NF B; Oxidative stress

Indexed keywords

BARSTAR; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); FREE RADICAL; GLUTATHIONE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTOXEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION; TISSUE LEVEL;

ANIMALS; HEART; LIPOPOLYSACCHARIDES; MALE; MYOCARDIUM; NF-KAPPA B; OLIGOPEPTIDES; OXIDATIVE STRESS; PEPTIDES, CYCLIC; PIPERIDINES; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; SIGNAL TRANSDUCTION;

EID: 84867759155     PISSN: 02315882     EISSN: 13384325     Source Type: Journal    
DOI: 10.4149/gpb_2012_031     Document Type: Article

References (31)

1. Abrahams W. (2001): Progress in clinical trials: encore. Clin. Cardiol. 24, 481-483 http://dx.doi.org/10.1002/clc.4960240612
2. Awane-Igata Y., Ikeda S., Watanabe T. (1997): Inhibitory effects of TAK-044 on endothelin induced vasoconstriction in various canine arteries and porcine coronary arteries: a comparison with selective ETA and ETB receptor antagonists. Br. J. Pharmacol. 120, 516-522 http://dx.doi.org/10.1038/sj.bjp. 0700925 (Pubitemid 27052852)
3. Callera G. E., Touyz R. M., Teixera S. A., Muscara M. N., Carvalho M. H., Fortes Z. B., Nigro D., Schiffrin E. L., Tostes R. C. (2003): ETa receptor blockade decreases vascular superoxide generation I DOCA-salt hypertension. Hypertension 42, 811-817 http://dx.doi.org/10.1161/01. HYP.0000088363.65943.6C (Pubitemid 37237330)
4. Cheng T. H., Shih N. L., Chen C. H., Lin H., Liu J. C., Chao H. H., Liou J. Y., Chen Y. L., Tsai H. W., Chen Y. S., Cheng C. F., Chen J. J. (2005): Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hypertrophy. J. Biomed. Sci. 12, 123-133 http://dx.doi.org/10.1007/s11373-004- 8168-6 (Pubitemid 40576770)
5. De Azevedo L. C., Park M., Noritomi D. T., Maciel A. T., Brunialti M. K., Salomão R. (2007): Characterization of an animal model of severe sepsis associated with respiratory dysfunction. Clinics (Sao Paulo) 62, 491-498 http://dx.doi.org/10.1590/S1807-59322007000400017
6. Dong F., Zhang X., Wold L. E., Ren Q., Zhang Z., Ren J. (2005): Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1. Br. J. Pharmacol. 145, 323-333 http://dx.doi.org/10.1038/sj.bjp. 0706193 (Pubitemid 40896077)
7. Elmarakby A. A., Dabbs Loomis E., Pollock J. S., Pollock D. M. (2004): ETA receptor blockade attenuates hypertension and decreases reactive oxygen species in ETB receptor-deficient rats. J. Cardiovasc. Pharmacol. 44, S7-10 http://dx.doi.org/10.1097/01.fc.0000166205.66555.40 (Pubitemid 40039632)
8. Forni M., Mazzola S., Ribeiro L. A., Pirrone F., Zannoni A., Bernardini C., Bacci M. L., Albertini M. (2005): Expression of endothelin-1 system in a pig model of endotoxic shock. Regul. Pept. 131, 89-96 http://dx.doi.org/10.1016/j. regpep. 2005.07.001 (Pubitemid 41392997)
9. Gee K., Kozlowski M., Kumar A. (2003): Tumor necrosis factoralpha induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells. J. Biol. Chem. 278, 37275-37287 http://dx.doi.org/10.1074/jbc. M302309200 (Pubitemid 37175244)
10. Goyal S. N., Bharti S., Arora S., Golechha M., Arya D. S. (2010): Endothelin receptor antagonist BQ-123 ameliorates myocardial ischemic-reperfusion injury in rats: a hemodynamic, biochemical, histopathological and electron microscopic evidence. Biomed. Pharmacother. 64, 639-646 http://dx.doi.org/10.1016/j.biopha.2010.06.001
11. Kähler J., Mendel S., Weckmüller J., Orzechowski H. D., Mittmann C., Köster R., Paul M., Meinertz T., Münzel T. (2000): Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter. J. Mol. Cell. Cardiol. 32, 1429-1437 http://dx.doi.org/ 10.1006/jmcc.2000.1178
12. Kell N. F., and Webb D. J. (2006): Clinical trials of endothelin antagonists in heart failure: A question of dose? Exp. Biol. Med. 231, 696-699 (Pubitemid 43845511)
13. Konrad D., Haney M., Johansson G., Wanecek M., Weitzberg E., Oldner A. (2007): Cardiac effects of endothelin receptor antagonism in endotoxemic pigs. Am. J. Physiol. Heart. Circ. Physiol. 293, H988-996 http://dx.doi.org/10.1152/ ajpheart.01023.2006 (Pubitemid 47254197)
14. Krause S. M., Lynch J. J., Stabilito I. I., Woltmann R. F. (1994): Intravenous administration of the endothelin-1 antagonist BQ-123 does not ameliorate myocardial ischaemic injury following acute coronary artery occlusion in the dog. Cardiovasc. Res. 28, 1672-1678 http://dx.doi.org/10.1093/cvr/28.11. 1672 (Pubitemid 24344141)
15. Liu H., Lee S. S. (2008): Nuclear factor-κB inhibition improves myocardial contractility in rats with cirrhotic cardiomyopathy. Liver. Int. 28, 640-648 http://dx.doi.org/10.1111/j.1478-3231.2008.01692.x (Pubitemid 351541095)
16. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. (1951): Protein measurement with the Folin phenol reagent. Bioch. Chem. 193, 76-85
17. Molenaar P., O'Reilly G., Sharkey A., Kuc R. E., Harding D. P., Plumpton C., Gresham G. A., Davenport A. P. (1993): Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium. Circ. Res. 72, 526-538 http://dx.doi.org/10.1161/01. RES.72.3.526 (Pubitemid 23052151)
18. Motawi T. K., Darwish H. A., Abd El Tawab A. M. (2011): Effects of caffeic acid phenethyl ester on endotoxin-induced cardiac stress in rats: A possible mechanism of protection. J. Biochem. Mol. Toxicol. 25, 84-94 http://dx.doi.org/10.1002/jbt.20362
19. Ozdemir R., Parlakpinar H., Polat A., Colak C., Ermis N., Acet A. (2006): Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury. Toxicology 219, 142-149 http://dx.doi.org/10.1016/j.tox.2005.11.022 (Pubitemid 43120714)
20. Piechota A., Goraca A. (2011): Protective effects of endothelin-A receptor antagonist BQ123 against LPS-induced oxidative stress in lungs. Pharmacol. Rep. 63, 494-500
21. Ritter C., Andrades M., Frota M. L. Jr., Bonatto F., Pinho R. A., Polydoro M., Klamt F., Pinheiro C. T., Menna-Barreto S. S., Moreira J. C., Dal-Pizzol F. (2003): Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation. Intensive. Care. Med. 29, 1782-1789 http://dx.doi.org/10.1007/s00134-003-1789-9 (Pubitemid 37373825)
22. Ruch W., Cooper P. H., Baggiolinii M. (1983): Assay of H2O2 production by macrophages and neurotrophils with homovanilic acid and horse-radish peroxidase. J. Immunol. Methods 63, 347-357 http://dx.doi.org/10.1016/S0022-1759 (83) 80008-8 (Pubitemid 13018061)
23. Sastry B. K. (2006): Pharmacologic treatment for pulmonary arterial hypertension. Curr. Opin. Cardiol. 21, 561-568 (Pubitemid 44624540)
24. 2+ channel function in the absence of apoptosis in ventricular myocytes. Circ. Res. 100, 1036-1044 http://dx.doi.org/10.1161/01. RES.0000263010.19273.48 (Pubitemid 46598928)
25. Wang H. H, Hsieh H. L., Yang C. M. (2010): Nitric oxide production by endothelin-1 enhances astrocytic migration via the tyrosine nitration of matrix metalloproteinase-9. J. Cell. Physiol. (in press)
26. Wölkart G., Stessel H., Saad Z., Kirchengast M., Brunner F. (2006): Cardioprotective effects of atrasentan, an endothelin-A receptor antagonist, but not of nitric oxide in diabetic mice with myocyte-specific overexpression of endothelial nitric oxide synthase. Br. J. Pharmacol. 148, 671-681 http://dx.doi.org/10.1038/sj.bjp. 0706772 (Pubitemid 43993057)
27. Wort S. J., Ito M., Chou P. C., McMaster S. K., Badiger R., Jazrawi E., De Souza P., Evans T. W., Mitchell J. A., Pinhu L., Ito K., Adcock I. M. (2009): Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites. J. Biol. Chem. 284, 24297-24305 http://dx.doi.org/10. 1074/jbc. M109.032524
28. Xia H. J., Dai D. Z., Dai Y. (2006): Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in l-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats. Life Sci. 79, 1812-1819 http://dx.doi.org/10.1016/j.lfs.2006.06.007 (Pubitemid 44441451)
29. Xu H., Lin L., Yuan W. J. (2003): Antiarrhythmic effect ofendothelin-A receptor antagonist on acute ischemic arrhythmia in isolated rat heart. Acta. Pharmacol. Sin. 24, 37-44 (Pubitemid 36090774)
30. Yagi K. (1986): A simple fluorometric assay for lipids peroxides in blood plasma. Biochem. Med. 15, 212-216 http://dx.doi.org/10.1016/0006-2944 (76) 90049-1
31. Yamamoto S., Matsumoto N., Kanazawa M., Fujita M., Takaoka M., Gariepy C. E., Yanagisawa M., Matsumura Y. (2005): Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and nor epinephrine overflow in rat hearts. Circulation 111, 302-309 http://dx.doi.org/10.1161/01. CIR.0000153351.86708.F7 (Pubitemid 40165336)