Protective effects of endothelin-A receptor antagonist BQ123 against LPS-induced oxidative stress in lungs

Pharmacological Reports

Volumn 63, Issue 2, 2011, Pages 494-500

  Piechota, Aleksandra ^a   Polańczyk, Andrzej ^b   Goraca, Anna ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

BQ 123; Endotoxic shock; Lung edema; Oxidative stress

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDE; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; ENZYME BLOOD LEVEL; ENZYME METABOLISM; LIPID PEROXIDATION; LUNG EDEMA; LUNG HOMOGENATE; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT;

EID: 79955937046     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(11)70516-3     Document Type: Article

References (35)

1. Andreeva, AV, Vaiskunaite R, Kutuzov MA, Profirovic J, Skidgel RA, Voyno-Yasenetskaya T: Novel mechanisms of G protein-dependent regulation of endothelial nitricoxide synthase. Mol Pharmacol, 2006, 69, 975-982. (Pubitemid 43363872)
2. Berger MM, Rozendal CS, Schieber C, Dehler, M, Zügel S, Bardenheuer HJ, Bärtsch P, Mairbäurl H: The effect of endothelin-1 on alveolar fluid clearance and pulmonary edema formation in the rat. Anesth Analg, 2009, 108, 225-231.
3. Bhavsar T, Liu XJ, Patel H, Stephani R, Cantor JO: Preferential recruitment of neutrophils by endothelin-1 in acute lung inflammation induced by lipopolysaccharide or cigarette smoke. Int J Chron Obstruct Pulmon Dis, 2008, 3, 477-481.
4. Callera GE, Touyz RM, Teixera SA, Muscara MN, Carvalho MH, Fortes ZB, Nigro D et al.: ETA receptor blockade decreases vascular superoxide generation I DOCA-salt hypertension. Hypertension, 2003, 42, 811-817. (Pubitemid 37237330)
5. Chen Y, Hanaoka M, Droma Y, Chen P, Voelkel NF, Kubo K: Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats. Eur Respir J, 2010, 35, 904-912.
6. Cheng TH, Shih NL, Chen SY, Wang DL, Chen JJ: Reactive oxygen species modulate endothelin-1-induced c-fos gene expression in cardiomyocytes. Cardiovasc Res, 1999, 41, 654-662. (Pubitemid 29130629)
7. Comellas AP, Briva A: Role of endothelin-1 in acute lung injury. Transl Res, 2009, 153, 63-71.
8. Dulin NO, Niu J, Browning DD, Ye RD, Voyno-Yasenetskaya T: Cyclic AMP-independent activation of protein kinase A by vasoactive peptides. J Biol Chem, 2001, 276, 20827-20830.
9. Ehrenreich H, Anderson RW, Fox CH, Rieckmann P, Hoffman GS, Travis WD, Coligan JE et al.: Endothelins, peptides with potent vasoactive properties, are produced by human macrophages. J Exp Med, 1990, 172, 1741-1748.
10. Feldstein C, Romero C: Role of endothelins in hypertension. Am J Ther, 2007, 14, 147-153. (Pubitemid 46597652)
11. Fujii Y, Magder S, Cernacek P, Goldberg P, Guo Y, Hussain S: Endothelin receptor blockage attenuates lipopolysaccharide-induced pulmonary nitric oxide production. Am J Respir Crit Care Med, 2000, 161, 982-989. (Pubitemid 30171761)
12. Goraca A, Józefowicz-Okonkwo G: Protective effects of early treatment with lipoic acid in LPS-induced lung injury in rats. J Physiol Pharmacol, 2007, 58, 541-549. (Pubitemid 47523096)
13. Goraca A, Skibska B: Beneficial effect of alpha-lipoic acid on lipopolysaccharide-induced oxidative stress in bronchoalveolar lavage fluid. J Physiol Pharmacol, 2008, 59, 379-386. (Pubitemid 351955759)
14. Huribal M, Cunningham ME, D'Aiuto ML, Pleban WE, McMillen MA: Endothelin-1 and prostaglandin E2 levels increase in patients with lung injury. J Am Coll Surg, 1995, 180, 318-322.
15. Kassuya CA, Rogerio AP, Calixto JB: The role of ETA and ETB receptor antagonists in acute and allergic inflammation in mice. Peptides, 2008, 29, 1329-1337.
16. Kim HJ, Lee HS, Chong YH, Kang JL: p38 Mitogen-activated protein kinase up-regulates LPS-induced NF-κB activation in the development of lung injury and RAW264.7 macrophages. Toxicology, 2006, 225, 36-47. (Pubitemid 44026641)
17. Kiriş I, Narin C, Gülmen S, Yilmaz N, Sütçü R, Kapucuoǧlu N: Endothelin receptor antagonism by tezosentan attenuates lung injury induced by aortic ischemiareperfusion. Ann Vasc Surg, 2009, 23, 382-391.
18. Kosmidou I, Karmpaliotis D, Kirtane AJ, Barron HV, Gibson M: Vascular endothelial growth factor in pulmonary edema: an update. J Thromb Thrombolysis, 2008, 25, 259-264. (Pubitemid 351772727)
19. Landgraf RG, Jancar S: Endothelin A receptor antagonist modulates lymphocyte and eosinophil infiltration, hyperreactivity and mucus in murine asthma. Int Immunopharmacol, 2008, 8, 1748-1753.
20. Mehanna A, Vitorino DC, Panis C, Blanco EE, Pinge- Filho P, Martins-Pinge MC: Cardiovascular and pulmonary effects of NOS inhibition in endotoxemic conscious rats subjected to swimming training. Life Sci, 2007, 81, 1301-1308. (Pubitemid 47539510)
21. Opal SM: The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis. Int J Med Microbiol, 2007, 297, 365-377.
22. Opitz CF, Ewert R, Kirch W, Pittrow D: Inhibition of endothelin receptors in the treatment of pulmonary arterial hypertension: does selectivity matter? Eur Heart J, 2008, 29, 1936-1948.
23. Piechota A, Pilańczyk A, Goraca A: Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress. Pharmacol Rep, 2010, 62, 28-34.
24. Resink TJ, Scott-Burden T, Bühler FR: Activation of multiple signal transduction pathways by endothelin in cultured human vascular smooth muscle cells. Eur J Biochem, 1990, 189, 415-421. (Pubitemid 20146027)
25. Rubanyi GM, Polokoff MA: Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev, 1994, 46, 325-415.
26. 2 production by macrophages and neurotrophils with homovanilic acid and horse-radish peroxidase. J Immunol Methods, 1983, 63, 347-357.
27. Sampaio AL, Rae GA, Henriques MG: Effects of endothelin ETA receptor antagonism on granulocyte and lymphocyte accumulation in LPS-induced inflammation. J Leukoc Biol, 2004, 76, 210-216. (Pubitemid 38857189)
28. Shen W, Gan J, Xu S, Jiang G, Wu H: Penehyclidine hydrochloride attenuates LPS-induced acute lung injury involvement of NF-κB pathway. Pharmacol Res, 2009, 60, 296-302.
29. Skibska B, Józefowicz-Okonkwo G, Goraca A: Protective effects of early administration of alpha-lipoic acid against lipopolysaccharide-induced plasma lipid peroxidation. Pharmacol Rep, 2006, 58, 399-404. (Pubitemid 44111075)
30. Teixeira CF, Jancar S, Lima WT, D'Orléans-Juste P, Sirois P: Association of endothelin with lung hemorrhage induced by immune complexes in rats. Inflammation, 2004, 28, 253-261. (Pubitemid 41204376)
31. Trachsel S, Deby-Dupont G, Maurenbrecher E, Nys M, Lamy M, Hedenstierna G: Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury. Crit Care, 2008, 12, R131.
32. Valenca SS, Silva Bezerra F, Lopes AA, Romana-Souza B, Marinho Cavalcante MC, Lima AB, Gonçalves Koatz VL, Porto LC: Oxidative stress in mouse plasma and lungs induced by cigarette smoke and lipopolysaccharide. Environ Res, 2008, 108, 199-204.
33. Yagi K: A simple fluorometric assay for lipids peroxides in blood plasma. Biochem Med, 1986, 15, 212-216.
34. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y et al.: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature, 1988, 332, 411-415. (Pubitemid 18090241)
35. Yang J, Qu JM, Summah H, Zhang J, Zhu YG, Jiang HN: Protective effects of imipramine in murine endotoxin-induced acute lung injury. Eur J Pharmacol, 2010, 638, 128-133.