The effects of particulate ambient air pollution on the murine umbilical cord and its vessels: A quantitative morphological and immunohistochemical study

Reproductive Toxicology

Volumn 34, Issue 4, 2012, Pages 598-606

  Veras, Mariana Matera ^a,b   Guimarães Silva, Rosane Maria ^a   Caldini, Elia Garcia ^a,b   Saldiva, Paulo H N ^a,b   Dolhnikoff, Marisa ^a,b   Mayhew, Terry M ^c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INAIRA Instituto Nacional de Avaliação Integrada de Risco Ambiental   (Brazil)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Collagen; Endothelin receptors; Immunohistochemistry; Isoprostane; Particulate air pollution; Stereology; Umbilical cord

Indexed keywords

COLLAGEN; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR; ISOPROSTANE DERIVATIVE;

AIR POLLUTION; ANIMAL CELL; ARTICLE; BIRTH WEIGHT; CELL STRUCTURE; CONNECTIVE TISSUE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FETUS WEIGHT; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LITTER SIZE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; QUANTITATIVE ANALYSIS; STEREOLOGY; UMBILICAL ARTERY; UMBILICAL CORD; UMBILICAL VEIN; VASOCONSTRICTION; YOLK SAC;

AIR POLLUTION; ANIMALS; COLLAGEN; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; PARTICULATE MATTER; PREGNANCY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; UMBILICAL CORD;

MURINAE; MUS;

EID: 84867747921     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2012.08.003     Document Type: Article

References (57)

1. Djemek J., Solanský I., Benes I., Lenícek J., Srám R.J. The impact of polycyclic aromatic hydrocarbons and fine particles on pregnancy outcome. Environmental Health Perspectives 2000, 108:1159-1164.
2. Šrám R.J., Binková B., Dejmek J., Bobak M. Ambient air pollution and pregnancy outcomes: a review of the literature. Environmental Health Perspectives 2005, 113:375-382.
3. Pereira L.A., Loomis D., Conceição G.M., Braga A.L., Arcas R.M., Kishi H.S., et al. Association between air pollution and intrauterine mortality in São Paulo, Brazil. Environmental Health Perspectives 1998, 106:325-329.
4. Veras M.M., Damaceno-Rodrigues N.R., Guimaräes Silva R.M., Scoriza J.N., Saldiva P.H.N., Caldini E.G., et al. Chronic exposure to fine particulate matter emitted by traffic affects reproductive and fetal outcomes in mice. Environmental Research 2009, 109:536-543.
5. Veras M.M., Damaceno-Rodrigues N.R., Caldini E.G., Ribeiro A.A.C.M., Mayhew T.M., Saldiva P.H.N., et al. Particulate urban air pollution affects the functional morphology of mouse placenta. Biology of Reproduction 2008, 79:578-584.
6. Nanaev A.K., Kohnen G., Milovanov A.P., Domogatsky S.P., Kaufmann P. Stromal differentiation and architecture of the human umbilical cord. Placenta 1997, 18:53-64.
7. Sobolewski K., Bankowski E., Chyczewski L., Jaworski S. Collagen and glycosaminoglycans of Wharton's jelly. Biology of the Neonate 1997, 71:11-21.
8. Wooding P., Burton G. Comparative placentation. Structures, functions and evolution 2008, Springer Verlag, Berlin/Heidelberg.
9. Sexton A.J., Turmaine M., Cai W.Q., Burnstock G. A study of the ultrastructure of developing human umbilical vessels. Journal of Anatomy 1996, 188:75-85.
10. Mu J., Adamson S.L. Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation. American Journal of Physiology-Heart and Circulatory Physiology 2006, 291:H1421-H1428.
11. Rennie M.Y., Whiteley K.J., Kulandavelu S., Adamson S.L., Sled J.G. 3D visualisation and quantification by microcomputed tomography of late gestational changes in the arterial and venous feto-placental vasculature of the mouse. Placenta 2007, 28:833-840.
12. Togni F.A., Araujo Júnior E., Vasques F.A., Moron A.F., Torloni M.R., Nardozza L.M. The cross-sectional area of umbilical cord components in normal pregnancy. International Journal of Gynaecology and Obstetrics 2007, 96:156-161.
13. Koech A., Ndungu B., Gichangi P. Structural changes in umbilical vessels in pregnancy induced hypertension. Placenta 2008, 29:210-214.
14. Pennati G. Biomechanical properties of the human umbilical cord. Biorheology 2001, 38:355-366.
15. Takechi K., Kuwabara Y., Mizuno M. Ultrastructural and immunohistochemical studies of Wharton's jelly umbilical cord cells. Placenta 1993, 14:235-245.
16. Di Naro E., Ghezzi F., Raio L., Franchi M., D'Addario V. Umbilical cord morphology and pregnancy outcome. European Journal of Obstetrics, Gynecology, and Reproductive Biology 2001, 96:150-157.
17. Weissman A., Jakobi P. Sonographic measurements of the umbilical cord in pregnancies complicated by gestational diabetes. Journal of Ultrasound in Medicine 1997, 16:691-694.
18. Inan S., Sanci M., Can D., Vatansever S., Oztekin O., Tinar S. Comparative morphological differences between umbilical cords from chronic hypertensive and preeclamptic pregnancies. Acta Medica Okayama 2002, 56:177-186.
19. Raio L., Ghezzi F., Di Naro E., Franchi M., Bolla D., Schneider H. Altered sonographic umbilical cord morphometry in early-onset preeclampsia. Obstetrics and Gynecology 2002, 100:311-316.
20. Pawlicka E., Bankowski E., Jaworski S. Elastin of the umbilical cord arteries and its alterations in EPH gestosis (preeclampsia). Biology of the Neonate 1999, 75:91-96.
21. Romanowicz L., Sobolewski K. Extracellular matrix components of the wall of umbilical cord vein and their alterations in pre-eclampsia. Journal of Perinatal Medicine 2000, 28:140-146.
22. Galewska Z., Bańkowski E., Romanowicz L., Jaworski S. Pre-eclampsia (EPH-gestosis)-induced decrease of MMP-s content in the umbilical cord artery. Clinica Chimica Acta 2003, 335:109-115.
23. Raio L., Ghezzi F., Di Naro E., Duwe D.G., Cromi A., Schneider H. Umbilical cord morphologic characteristics and umbilical artery Doppler parameters in intrauterine growth-restricted fetuses. Journal of Ultrasound in Medicine 2003, 22:1341-1347.
24. Burkhardt T., Matter C.M., Lohmann C., Cai H., Lüscher T.F., Zisch A.H., et al. Decreased umbilical artery compliance and IGF-I plasma levels in infants with intrauterine growth restriction - implications for fetal programming of hypertension. Placenta 2009, 30:136-141.
25. Yoshimatsu J., Goto K., Nasu K., Narahara H., Miyakawa I. Intrauterine growth restriction and the proliferation of smooth muscle cells in umbilical vessels. Australian & New Zealand Journal of Obstetrics & Gynaecology 2006, 46:212-216.
26. Privalova L.I., Malykh O.L., Matiukhina G.V., Gnezdilova S.V. The umbilical blood levels of lead and some other toxic metals as a biomarker of environment-induced exposure. Gigiena i Sanitariia 2007, 3:68-70.
27. Gundersen H.J.G., Jensen E.B. The efficiency of systematic sampling in stereology and its prediction. Journal of Microscopy 1987, 147:229-263.
28. Mayhew T.M. Taking tissue samples from the placenta: an illustration of principles and strategies. Placenta 2008, 29:1-14.
29. Milne G.L., Yin H., Morrow J.D. Human biochemistry of the isoprostane pathway. Journal of Biological Chemistry 2008, 283:15533-15537.
30. Hynynen M.M., Khalil R.A. The vascular endothelin system in hypertension-recent patents and discoveries. Recent Patents on Cardiovascular Drug Discovery 2006, 1:95-108.
31. Ghosh K.G., Ghosh S.N., Gupta A.B. Tensile properties of the human umbilical cord. Indian Journal of Medical Research 1984, 79:538-541.
32. Filiz A.A., Rahime B., Keskin H.L., Esra A.K. Positive correlation between the quantity of Wharton's jelly in the umbilical cord and birth weight. Taiwanese Journal of Obstetrics & Gynecology 2011, 50(1):33-36.
33. Blanco M.V., Vega H.R., Guerri-Guttenberg R.A., Giuliano R., Grana D.R., Azzato F., et al. Histopathology and histomorphometry of umbilical cord blood vessels. Findings in normal and high risk pregnancies. Artery Research 2011, 5(2):50-57.
34. Coan P.M., Ferguson-Smith A.C., Burton G.J. Developmental dynamics of the definitive mouse placenta assessed by stereology. Biology of Reproduction 2004, 70:1806-1813.
35. Link G., Clark K.E., Lang U. Umbilical blood flow during pregnancy: evidence for decreasing placental perfusion. American Journal of Obstetrics and Gynecology 2007, 196:489e1-489e7.
36. Mayhew T.M. Stereology and the placenta: where's the point? - a review. Placenta 2006, 20(Suppl. A):S17-S25.
37. Ong S.S., Baker P.N., Mayhew T.M., Dunn W.R. Remodeling of myometrial radial arteries in preeclampsia. American Journal of Obstetrics and Gynecology 2005, 192:572-579.
38. Kedzierski R.M., Yanagisawa M. Endothelin system: the double-edged sword in health and disease. Annual Review of Pharmacology and Toxicology 2001, 41:851-876.
39. Lipa J.E., Neligan P.C., Perreault T.M., Baribeau J., Levine R.H., et al. Vasoconstrictor effect of endothelin-1 in human skin: role of ETA and ETB receptors. American Journal of Physiology-Heart and Circulatory Physiology 1999, 276:H359-H367.
40. Batra V.K., McNeill J.R., Xu Y., Wilson T.W., Gopalkrishan V. ETB receptors on aortic smooth muscle cells of spontaneously hypertensive rats. American Journal of Physiology-Cell Physiology 1993, 264:C479-C484.
41. Peters A., Döring A., Wichmann H.E., Koenig W. Increased plasma viscosity during an air pollution episode: a link to mortality. Lancet 1997, 349:1582-1587.
42. Barker D.J., Osmond C., Kajantie E., Eriksson J.G. Growth and chronic disease: findings in the Helsinki Birth Cohort. Annals of Human Biology 2009, 36:445-458.
43. García-Huidobro D.N., García-Huidobro M.T., Huidobro-Toro J.P. Vasomotion in human umbilical and placental veins: role of gap junctions and intracellular calcium reservoirs in their synchronous propagation. Placenta 2007, 28:328-338.
44. Mildenberger E., Siegel G., Versmold H.T. Prostanoids contribute to the oxygen-dependent regulation of vascular tone of human umbilical vein. Journal of Perinatal Medicine 2004, 32:149-154.
45. Thomson E., Kumarathasan P., Vincent R. Pulmonary expression of preproET-1 and preproET-3 mRNAs is altered reciprocally in rats after inhalation of air pollutants. Experimental Biology and Medicine 2006, 231:979-984.
46. Cherng T.W., Campen M.J., Knuckles T.L., Gonzalez Bosc L., Kanagy N.L. Impairment of coronary endothelial cell ET(B) receptor function after short-term inhalation exposure to whole diesel emissions. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 2009, 297:R640-R647.
47. Bodelsson G., Laursen M., Stjernquist M. Oxygen promotes contraction by endothelin-1 in human umbilical artery. Human Reproduction 1996, 11:2767-2768.
48. Perera F.P., Jedrychowski W., Rauh V., Whyatt R.M. Molecular epidemiologic research on the effects of environmental pollutants on the fetus. Environmental Health Perspectives 1999, 107(Suppl. 3):451-460.
49. Topinka J., Milcova A., Libalova H., Novakova Z., Rossner P., Balascak I., et al. Biomarkers of exposure to tobacco smoke and environmental pollutants in mothers and their transplacental transfer to the foetus. Part I: bulky DNA adducts. Mutation Research 2009, 669:13-19.
50. Rossner P., Milcova A., Libalova H., Novakova Z., Topinka J., Balascak I., et al. Biomarkers of exposure to tobacco smoke and environmental pollutants in mothers and their transplacental transfer to the foetus. Part II: oxidative damage. Mutation Research 2009, 669:20-26.
51. Obwegeser R., Oguogho A., Ulm M., Berghammer P., Sinzinger H. Maternal cigarette smoking increases F2-isoprostanes and reduces prostacyclin and nitric oxide in umbilical vessels. Prostaglandins and Other Lipid Mediators 1999, 57:269-279.
52. Weinberger B., Nisar S., Anwar M., Ostfeld B., Hegyi T. Lipid peroxidation in cord blood and neonatal outcome. Pediatrics International 2006, 48:479-483.
53. Walsh S.W., Vaughan J.E., Wang Y., Roberts L.J. Placental isoprostane is significantly increased in preeclampsia. FASEB Journal 2000, 14:1289-1296.
54. Campen M.J., Lund A.K., Knuckles T.L., Conklin D.J., Bishop B., Young D., et al. Inhaled diesel emissions alter atherosclerotic plaque composition in ApoE(-/-) mice. Toxicology and Applied Pharmacology 2010, 242:310-317.
55. Bogoni G., Rizzi A., Calo G., Campobasso C., D'Orleans-Juste P., Regoli D. Characterization of endothelin receptors in the human umbilical artery and vein. British Journal of Pharmacology 1996, 119:1600-1604.
56. 2 consumption in sheep. American Journal of Physiology 1996, 274:H16-H23.
57. Brook R.D., Brook J.R., Urch B., Vincent R., Rajagopalan S., Silverman F. Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults. Circulation 2002, 105(13):1534-1536.