Maternal cigarette smoking increases F2-isoprostanes and reduces prostacyclin and nitric oxide in umbilical vessels

Prostaglandins and Other Lipid Mediators

Volumn 57, Issue 4, 1999, Pages 269-279

  Obwegeser, Reinhard ^a   Oguogho, Anthony ^b   Ulm, Martin ^a   Berghammer, Peter ^b   Sinzinger, Helmut ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Cigarette smoking; F2 isoprostanes; Nitric oxide; Prostacyclin; Umbilical cord

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; ARGININE; CITRULLINE; ISOPROSTANE DERIVATIVE; NITRIC OXIDE; PROSTACYCLIN;

ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; MATERNAL BEHAVIOR; NEWBORN; UMBILICAL ARTERY; UMBILICAL CORD; UMBILICAL VEIN; VASOCONSTRICTION; VASODILATATION;

EID: 0033067073     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(99)00011-8     Document Type: Article

References (23)

1. Johnston C. Cigarette smoking and the outcome of human pregnancies a status report on the consequences . Clin Toxicol. 18:1981;189-209.
2. Tuvemo T. Role of prostaglandins, prostacyclin and thromboxanes in the control of umbilical-placental circulation. Semin Perinatol. 4:1980;91-95.
3. Moncada S., Vane J.R. Unstable metabolites of arachidonic acid and their role in haemostasis and thrombosis. Br Med Bull. 34:1978;129-135.
4. Dadak Ch, Kefalides A., Sinzinger H., Weber G. Reduced umbilical artery prostacyclin formation in complicated pregnancies. Am J Obstet Gynecol. 144:1982;792-795.
5. Asmussen I. Fetal cardiovascular system as influenced by maternal smoking. Clin Cardiol. 2:1979;246-256.
6. Silberbauer K., Sinzinger H., Winter M. Prostacyclin production by vascular smooth-muscle cells. Lancet. i:1978;1356-1357.
7. Dadak Ch, Leitner Ch, Sinzinger H., Silberbauer H. Diminished prostacyclin formation in umbilical arteries of babies born to women who smoke. Lancet. i:1981;94.
8. Ahlsten G., Ewald U., Tuvemo T. Maternal smoking reduces prostacyclin formation in human umbilical arteries. Acta Obstet Gynecol Scand. 65:1986;645-649.
9. Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide physiology, pathophysiology and pharmacology . Pharmacol Rev. 43:1991;109-141.
10. Ulm M.R., Plöckinger B., Pirich Ch, Gryglewski R., Sinzinger H.F. Umbilical arteries of babies born to cigarette smokers generate less prostacyclin and contain less arginine and citrulline compared with those of babies born to control subjects. Am J Obstet Gynecol. 172:1995;1485-1487.
11. Church D.F., Pryor W.A. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect. 64:1985;111-126.
12. Aghajanian A.A., Oguogho A., Sinzinger H. Isoprostane, eine neue Substanzgruppe in der Angiologie - in der Zukunft von Bedeutung? VASA. 26:1997;65-69.
13. Morrow J.D., Roberts L.J. II. The isoprostanes - current knowledge and directions for future research. Biochem Pharmacol. 51:1996;1-9.
14. 2-isoprostanes) in smokers. N Engl J Med. 332:1995;1198-1203.
15. Palmer R.M.J., Ashton D.S., Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature. 333:1988;664-666.
16. Einarsson S., Josefsson B., Lagerkvist S. Determination of aminoacids with 9-fluorenylmethyl chloroformate and reversed-phase high-performance liquid chromatography. J Chromatogr. 282:1983;609-618.
17. Barden A., Beilin L.J., Ritchie J., Croft K.D., Walters B.N., Micheal C.A. Plasma and urinary 8-iso-prostane as an indicator of lipid peroxidation in pre-eclampsia and normal pregnancy. Clin Sci Colch. 91:1996;711-718.
18. Wennmalm A. Interaction of nicotine and prostaglandins in the cardiovascular system. Prostaglandins. 23:1982;139-144.
19. Remuzzi G., Marchesi D., Zoja C., et al. Reduced umbilical and placental prostacyclin in severe preeclampsia. Prostaglandins. 20:1980;105-110.
20. Stuart M.J., Sunderji S.G., Yambo T., et al. Decreased prostacyclin production a characteristic of chronic placental insufficiency syndromes . Lancet. i:1981;1126.
21. Mäkilä U.M., Jouppila P., Kirkinen P., Viinikka L. Relation between umbilical prostacyclin production and blood-flow in the fetus. Lancet. i:1983;728-729.
22. Mäkilä U.M., Viinikka L., Ylikorkala O. Evidence that prostacyclin deficiency is a specific feature in preeclampsia. Am J Obstet Gynecol. 148:1984;772-774.
23. Reilly M., Delanty N., Lawson J.A., Fitzgerald G.A. Modulation of oxidant stress in vivo in chronic cigarette smokers. Circulation. 94:1996;19-25.