Photoexcitation of tumor-targeted corroles induces singlet oxygen-mediated augmentation of cytotoxicity

Journal of Controlled Release

Volumn 163, Issue 3, 2012, Pages 368-373

  Hwang, Jae Youn ^a,c   Lubow, David J ^a   Chu, David ^a   Sims, Jessica ^a   Alonso Valenteen, Felix ^a   Gray, Harry B ^d   Gross, Zeev ^d,e   Farkas, Daniel L ^b,d   Medina Kauwe, Lali K ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of Southern California ^*  (United States)

^d CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^e TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

A sulfonated gallium(III) corrole; Drug delivery; Nanoparticles; Photoexcitation; Singlet oxygen; Tumor targeting

Indexed keywords

APOPTOTIC CELL DEATH; CELL DAMAGE; CELLULAR MECHANISMS; CORROLES; CYTOCHROME C; FLUORESCENCE OPTICAL IMAGING; IN-VIVO; LIGHT IRRADIATIONS; MITOCHONDRIAL DAMAGE; SIMULTANEOUS DETECTION; SINGLET OXYGEN; THERAPEUTIC APPLICATION; TUMOR TARGETING;

CELL DEATH; DRUG DELIVERY; FLUORESCENCE; IRRADIATION; NANOPARTICLES; OXYGEN; PHOTOEXCITATION; POLYPYRROLES;

TUMORS;

CYTOCHROME C; HERGA; NANOPARTICLE; SINGLET OXYGEN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DAMAGE; CYTOTOXICITY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; IN VIVO STUDY; LIGHT EXPOSURE; MITOCHONDRION; PHOTOEXCITATION; PRIORITY JOURNAL; PROTEIN SECRETION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; HUMANS; LIGHT; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NANOPARTICLES; NEOPLASMS; PORPHYRINS; SINGLET OXYGEN;

EID: 84867744682     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.09.015     Document Type: Article

References (28)

1. P. Rivera Gil, D. Huhn, L.L. del Mercato, D. Sasse, and W.J. Parak Nanopharmacy: inorganic nanoscale devices as vectors and active compounds Pharmacol. Res. 62 2010 115 125
2. L. Wang, M.B. O'Donoghue, and W. Tan Nanoparticles for multiplex diagnostics and imaging Nanomedicine (Lond.) 1 2006 413 426
3. T.J. Dougherty, C.J. Gomer, B.W. Henderson, G. Jori, D. Kessel, M. Korbelik, J. Moan, and Q. Peng Photodynamic therapy J. Natl. Cancer Inst. 90 1998 889 905 (Pubitemid 28304157)
4. L.D. Via, and S.M. Magno Photochemotherapy in the treatment of cancer Curr. Med. Chem. 8 2001 1405 1418 (Pubitemid 32894007)
5. H. Agadjanian, J. Ma, A. Rentsendorj, V. Valluripalli, J.Y. Hwang, A. Mahammed, D.L. Farkas, H.B. Gray, Z. Gross, and L.K. Medina-Kauwe Tumor detection and elimination by a targeted gallium corrole Proc. Natl. Acad. Sci. U.S.A. 106 2009 6105 6110
6. H. Agadjanian, J.J. Weaver, A. Mahammed, A. Rentsendorj, S. Bass, J. Kim, I.J. Dmochowski, R. Margalit, H.B. Gray, Z. Gross, and L.K. Medina-Kauwe Specific delivery of corroles to cells via noncovalent conjugates with viral proteins Pharm. Res. 23 2006 367 377 Epub 2006 Jan 2019 (Pubitemid 43237866)
7. R. Paolesse Syntheses of corroles K.M. Kadish, K.M. Smith, R. Guilard, The Porphyrin Handbook Vol. II 2000 Academic Press New York 201 232
8. J.L. Sessler, and S.J. Weghorn Expanded, Contracted, & Isomeric Porphyrins 1997 Pergamon Oxford
9. J.Y. Hwang, J. Lubow, D. Chu, J. Ma, H. Agadjanian, J. Sims, H.B. Gray, Z. Gross, D.L. Farkas, and L.K. Medina-Kauwe A mechanistic study of tumor-targeted corrole toxicity Mol. Pharm. 8 2011 2233 2243
10. L.K. Medina-Kauwe, N. Kasahara, and L. Kedes 3PO, a novel nonviral gene delivery system using engineered Ad5 penton proteins Gene Ther. 8 2001 795 803 (Pubitemid 32509794)
11. L.K. Medina-Kauwe, M. Maguire, N. Kasahara, and L. Kedes Nonviral gene delivery to human breast cancer cells by targeted Ad5 penton proteins Gene Ther. 8 2001 1753 1761 (Pubitemid 34100575)
12. J.Y. Hwang, S. Wachsmann-Hogiu, V.K. Ramanujan, J. Ljubimova, Z. Gross, H.B. Gray, L.K. Medina-Kauwe, and D.L. Farkas A multimode optical imaging system for preclinical applications in vivo: technology development, multiscale imaging, and chemotherapy assessment Mol. Imaging Biol. 14 2012 431 442
13. J.Y. Hwang, S. Wachsmann-Hogiu, V.K. Ramanujan, A.G. Nowatzyk, Y. Koronyo, L.K. Medina-Kauwe, Z. Gross, H.B. Gray, and D.L. Farkas Multimodal wide-field two-photon excitation imaging: characterization of the technique for in vivo applications Biomed. Opt. Express 2 2011 356 364
14. L.K. Medina-Kauwe Endocytosis of adenovirus and adenovirus capsid proteins Adv. Drug Deliv. Rev. 55 2003 1485 1496 (Pubitemid 37464574)
15. H. Agadjanian, D. Chu, J.Y. Hwang, S. Wachsmann-Hogiu, A. Rentsendorj, L. Song, V. Valluripalli, J. Lubow, J. Ma, B. Sharifi, D.L. Farkas, and L.K. Medina-Kauwe Chemotherapy targeting by DNA capture in viral protein particles Nanomedicine (Lond.) 7 2012 335 352
16. J.Y. Hwang, D.J. Lubow, J.D. Sims, H.B. Gray, A. Mahammed, Z. Gross, L.K. Medina-Kauwe, and D.L. Farkas Investigating photoexcitation-induced mitochondrial damage by chemotherapeutic corroles using multimode optical imaging J. Biomed. Opt. 17 2012 015003
17. R.C. Scaduto Jr., and L.W. Grotyohann Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives Biophys. J. 76 1999 469 477 (Pubitemid 29202474)
18. C. Fink, F. Morgan, and L.M. Loew Intracellular fluorescent probe concentrations by confocal microscopy Biophys. J. 75 1998 1648 1658 (Pubitemid 28455161)
19. A. Thompson, H.H. Seliger, and G.H. Posner Chemiluminescent probes for singlet oxygen in biological reactions Methods Enzymol. 133 1986 569 584
20. I. Luobeznova, M. Raizman, I. Goldberg, and Z. Gross Synthesis and full characterization of molybdenum and antimony corroles and utilization of the latter complexes as very efficient catalysts for highly selective aerobic oxygenation reactions Inorg. Chem. 45 2006 386 394
21. G. Palumbo Photodynamic therapy and cancer: a brief sightseeing tour Expert Opin. Drug Deliv. 4 2007 131 148
22. C.K. Lim, J. Shin, I.C. Kwon, S.Y. Jeong, and S. Kim Iodinated photosensitizing chitosan: self-assembly into tumor-homing nanoparticles with enhanced singlet oxygen generation Bioconjug. Chem. 2012 Apr 27 (Epub ahead of print).
23. D. Kowalska, X. Liu, U. Tripathy, A. Mahammed, Z. Gross, S. Hirayama, and R.P. Steer Ground- and excited-state dynamics of aluminum and gallium corroles Inorg. Chem. 48 2009 2670 2676
24. M. Ott, J.D. Robertson, V. Gogvadze, B. Zhivotovsky, and S. Orrenius Cytochrome c release from mitochondria proceeds by a two-step process Proc. Natl. Acad. Sci. U.S.A. 99 2002 1259 1263 (Pubitemid 34136480)
25. J.D. Robertson, S. Orrenius, and B. Zhivotovsky Review: nuclear events in apoptosis J. Struct. Biol. 129 2000 346 358 (Pubitemid 30481376)
26. X.-F. Zhanga, and Y. Rong Silicon tetrabenzotriaza corrole and silicon phthalocyanine: synthesis, photophysics and singlet oxygen generation J. Photochem. Photobiol., A. Chem. 222 2011 141 145
27. B. Ventura, A.D. Esposti, B. Koszarna, D.T. Gryko, and L. Flamigni Photophysical characterization of free-base corroles, promising chromophores for light energy conversion and singlet oxygen generation New J. Chem. 29 2005 1559 1566 (Pubitemid 41807643)
28. L. Shi, H.Y. Liu, L.P. Si, K.M. Peng, L.L. You, H. Wang, L. Zhang, L.N. Ji, C.K. Chang, and H.F. Jiang The heavy atom effect on photocleavage of DNA by mono-hydroxyl halogenated corroles Chin. Chem. Lett. 21 2010 373 375