A mechanistic study of tumor-targeted corrole toxicity

Molecular Pharmaceutics

Volumn 8, Issue 6, 2011, Pages 2233-2243

  Hwang, Jae Youn ^a   Lubow, Jay ^a   Chu, David ^a   Ma, Jun ^a   Agadjanian, Hasmik ^a   Sims, Jessica ^a   Gray, Harry B ^b   Gross, Zeev ^c   Farkas, Daniel L ^a,b,d   Medina Kauwe, Lali K ^a,e  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^d University of Southern California ^*  (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

corrole; cytoskeleton; gallium; heregulin; HerGa; mechanism; mitochondria; superoxide; targeting; tumor

Indexed keywords

MACROCYCLIC COMPOUND; PACLITAXEL; PROTEIN HERGA; SUPEROXIDE; TIRON; UNCLASSIFIED DRUG;

ARTICLE; CELL PH; CONTROLLED STUDY; CYTOSKELETON; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG UPTAKE; ENDOSOME; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL;

CELL DEATH; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOTOXINS; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; NEOPLASMS; PACLITAXEL; PORPHYRINS;

EID: 82955229584     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200094w     Document Type: Article

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