Real-time and spatial quantification using contrast-enhanced ultrasonography of spinal cord perfusion during experimental spinal cord injury

Spine

Volumn 37, Issue 22, 2012, Pages

  Soubeyrand, Marc ^a,b   Laemmel, Elisabeth ^a   Dubory, Arnaud ^a,b   Vicaut, Eric ^a   Court, Charles ^b   Duranteau, Jacques ^a,b  

^a Laboratoire d'Etude de la Microcirculation   (France)

^b BICÊTRE HOSPITAL   (France)

Author keywords

contrast agents; ischemia; regional blood fl ow; spinal cord injury; ultrasonography

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTRAST ENHANCEMENT; ECHOGRAPHY; EXPERIMENTAL STUDY; MALE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RAT; SPINAL CORD BLOOD FLOW; SPINAL CORD HEMORRHAGE; SPINAL CORD INJURY;

ANIMALS; DISEASE MODELS, ANIMAL; HEMORRHAGE; MALE; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; REPRODUCIBILITY OF RESULTS; SPINAL CORD; SPINAL CORD DISEASES; SPINAL CORD INJURIES; TIME FACTORS; ULTRASONOGRAPHY;

EID: 84867742742     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318269790f     Document Type: Article

References (28)

1. Sekhon LH, Fehlings MG. Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine (Phila Pa 1976) 2001; 26: S2-12. (Pubitemid 34019773)
2. Wyndaele M, Wyndaele JJ. Incidence, prevalence and epidemiology of spinal cord injury: What learns a worldwide literature survey? Spinal Cord 2006; 44: 523-9. (Pubitemid 44338756)
3. Cadotte DW, Fehlings MG. Spinal cord injury: A systematic review of current treatment options. Clin Orthop Relat Res 469: 732-41.
4. Mautes AE, Weinzierl MR, Donovan F, et al. Vascular events after spinal cord injury: Contribution to secondary pathogenesis. Phys Ther 2000; 80: 673-87. (Pubitemid 30441697)
5. Hamamoto Y, Ogata T, Morino T, et al. Real-time direct measurement of spinal cord blood flow at the site of compression: Relationship between blood flow recovery and motor deficiency in spinal cord injury. Spine 2007; 32: 1955-62. (Pubitemid 47300996)
6. McDonald JW, Sadowsky C. Spinal-cord injury. Lancet 2002; 359: 417-25. (Pubitemid 34158956)
7. Blight AR. Cellular morphology of chronic spinal cord injury in the cat: Analysis of myelinated axons by line-sampling. Neuroscience 1983; 10: 521-43. (Pubitemid 13019585)
8. Horn EM, Theodore N, Assina R, et al. The effects of intrathecal hypotension on tissue perfusion and pathophysiological outcome after acute spinal cord injury. Neurosurg Focus 2008; 25: E12.
9. Carlson GD, Gorden CD, Nakazawa S, et al. Sustained spinal cord compression: Part II: Effect of methylprednisolone on regional blood flow and recovery of somatosensory evoked potentials. J Bone Joint Surg Am 2003; 85-A: 95-101. (Pubitemid 36537979)
10. Postema M, Schmitz G. Bubble dynamics involved in ultrasonic imaging. Expert Rev Mol Diagn 2006; 6: 493-502. (Pubitemid 44174350)
11. Quaia E. Microbubble ultrasound contrast agents: An update. Eur Radiol 2007; 17: 1995-2008. (Pubitemid 47097457)
12. Wallace MC, Tator CH, Frazee P. Relationship between posttraumatic ischemia and hemorrhage in the injured rat spinal cord as shown by colloidal carbon angiography. Neurosurgery 1986; 18: 433-9. (Pubitemid 16073558)
13. Bullock R, Fujisawa H. The role of glutamate antagonists for the treatment of CNS injury. J Neurotrauma 1992; 9: S443-62.
14. Noble LJ, Wrathall Jr. Correlative analyses of lesion development and functional status after graded spinal cord contusive injuries in the rat. Exp Neurol 1989; 103: 34-40. (Pubitemid 19041045)
15. Bozzo A, Marcoux J, Radhakrishna M, et al. The role of magnetic resonance imaging in the management of acute spinal cord injury. J Neurotrauma; 28: 1401-11.
16. Guha A, Tator CH, Rochon J. Spinal cord blood flow and systemic blood pressure after experimental spinal cord injury in rats. Stroke 1989; 20: 372-7. (Pubitemid 19080095)
17. Griffiths IR, Trench JG, Crawford RA. Spinal cord blood flow and conduction during experimental cord compression in normotensive and hypotensive dogs. J Neurosurg 1979; 50: 353-60. (Pubitemid 9138073)
18. Ducker TB, Assenmacher DR. Microvascular response to experimental spinal cord trauma. Surg Forum 1969; 20: 428-30.
19. Heiss WD. The concept of the penumbra: Can it be translated to stroke management ? Int J Stroke 2010; 5: 290-5.
20. Mattson MP, Duan W, Pedersen WA, et al. Neurodegenerative disorders and ischemic brain diseases. Apoptosis 2001; 6: 69-81. (Pubitemid 32233956)
21. Ginsberg MD. The new language of cerebral ischemia. AJNR Am J Neuroradiol 1997; 18: 1435-45. (Pubitemid 30413958)
22. Broughton BR, Reutens DC, Sobey CG. Apoptotic mechanisms after cerebral ischemia. Stroke 2009; 40: E331-9.
23. Bassingthwaighte JB, Malone MA, Moffett TC, et al. Validity of microsphere depositions for regional myocardial flows. Am J Physiol 1987; 253: H184-93.
24. Drescher WR, Weigert KP, Bunger MH, et al. Spinal blood flow in 24-hour megadose glucocorticoid treatment in awake pigs. J Neurosurg 2003; 99: 286-90.
25. Westergren H, Farooque M, Olsson Y, et al. Spinal cord blood flow changes following systemic hypothermia and spinal cord compression injury: An experimental study in the rat using Laser-Doppler flowmetry. Spinal Cord 2001; 39: 74-84. (Pubitemid 32226161)
26. Ueda Y, Kawahara N, Tomita K, et al. Infl uence on spinal cord blood flow and function by interruption of bilateral segmental arteries at up to three levels: Experimental study in dogs. Spine (Phila Pa 1976) 2005; 30: 2239-43. (Pubitemid 41504891)
27. Golanov EV, Reis DJ. Contribution of oxygen-sensitive neurons of the rostral ventrolateral medulla to hypoxic cerebral vasodilatation in the rat. J Physiol 1996; 495: 201-16. (Pubitemid 26288465)
28. Anderson DK, Nicolosi GR, Means ED, et al. Effects of laminectomy on spinal cord blood flow. J Neurosurg 1978; 48: 232-8. (Pubitemid 8269970)