Community of protein complexes impacts disease association

European Journal of Human Genetics

Volumn 20, Issue 11, 2012, Pages 1162-1167

  Wang, Qianghu ^a   Liu, Weisha ^a   Ning, Shangwei ^a   Ye, Jingrun ^a   Huang, Teng ^a   Li, Yan ^a   Wang, Peng ^a   Shi, Hongbo ^a   Li, Xia ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

disease comorbidity; disease disease association; human disease network; protein complex

Indexed keywords

APOLIPOPROTEIN E3; EMERIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; MULTIPROTEIN COMPLEX; NOTCH RECEPTOR; PROTEIN MSH2; THROMBOCYTE ACTIVATING FACTOR; TRANSCRIPTION FACTOR HES 1;

ADRENAL CORTEX CARCINOMA; ADRENOLEUKODYSTROPHY; ALZHEIMER DISEASE; AORTA VALVE DISEASE; ARTICLE; BLOOM SYNDROME; CAFFEY DISEASE; COMORBIDITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DYSAUTONOMIA; GENE PRODUCT; HISTIOCYTOMA; HUMAN; HUNTINGTON CHOREA; INFORMATION PROCESSING; MALIGNANT NEOPLASTIC DISEASE; MUIR TORRE SYNDROME; OPTIC NERVE ATROPHY; PARATHYROID ADENOMA; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; REFSUM DISEASE; RHABDOID TUMOR; THROMBOPHILIA; TYROSINEMIA; VAN DER WOUDE SYNDROME; WALKER WARBURG SYNDROME; XERODERMA PIGMENTOSUM;

DISEASE; GENETIC ASSOCIATION STUDIES; GENOME, HUMAN; HUMANS; MULTIPROTEIN COMPLEXES;

EID: 84867742082     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2012.74     Document Type: Article

References (32)

1. Barabasi AL, Oltvai ZN: Network biology: understanding the cell's functional organization. Nat Rev Genet 2004; 5: 101-113.
2. Friedman A, Perrimon N: Genetic screening for signal transduction in the era of network biology. Cell 2007; 128: 225-231.
3. Barabasi AL, Gulbahce N, Loscalzo J: Network medicine: a network-based approach to human disease. Nat Rev Genet 2011; 12: 56-68.
4. Oti M, Brunner HG: The modular nature of genetic diseases. Clin Genet 2007; 71: 1-11.
5. Barabasi AL: Network medicine from obesity to the 'diseasome'. N Engl J Med 2007; 357: 404-407.
6. Loscalzo J, Kohane I, Barabasi AL: Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Mol Syst Biol 2007; 3: 124.
7. de Winter JP, van der Weel L, de Groot J et al: The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG. Hum Mol Genet 2000; 9: 2665-2674.
8. D'Andrea AD: The Fanconi anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers. Cell Cycle 2003; 2: 290-292.
9. Lamb J, Crawford ED, Peck D et al: The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006; 313: 1929-1935.
10. Lage K, Karlberg EO, Storling ZM et al: A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 2007; 25: 309-316.
11. Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabasi AL: The human disease network. Proc Natl Acad Sci USA 2007; 104: 8685-8690.
12. Lee DS, Park J, Kay KA, Christakis NA, Oltvai ZN, Barabasi AL: The implications of human metabolic network topology for disease comorbidity. Proc Natl Acad Sci USA 2008; 105: 9880-9885.
13. Hamosh A, Scott AF, Amberger JS, Bocchini CA, McKusick VA: Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res 2005; 33: D514-D517.
14. Park J, Lee DS, Christakis NA, Barabasi AL: The impact of cellular networks on disease comorbidity. Mol Syst Biol 2009; 5: 262.
15. Ruepp A, Waegele B, Lechner M et al: CORUM: the comprehensive resource of mammalian protein complexes. Nucleic Acids Res 2009; 38: D497-D501.
16. Mewes HW, Dietmann S, Frishman D et al: MIPS: analysis and annotation of genome information in 2007. Nucleic Acids Res 2008; 36: D196-D201.
17. Lauderdale DS, Furner SE, Miles TP, Goldberg J: Epidemiologic uses of Medicare data. Epidemiol Rev 1993; 15: 319-327.
18. Mitchell JB, Bubolz T, Paul JE et al: Using Medicare claims for outcomes research. Med Care 1994; 32: JS38-JS51.
19. Hidalgo CA, Blumm N, Barabasi AL, Christakis NA: A dynamic network approach for the study of human phenotypes. PLoS Comput Biol 2009; 5: e1000353.
20. Thissen D, Steinberg L, Kuang D: Quick and easy implementation of the Benjamini-Hochberg procedure for controlling the false positive rate in multiple comparisons. J Educ Behav Stat 2002; 27: 77-83.
21. Li Y, Agarwal P: A pathway-based view of human diseases and disease relationships. PLoS One 2009; 4: e4346.
22. Szilagyi A, Grimm V, Arakaki AK, Skolnick J: Prediction of physical protein-protein interactions. Phys Biol 2005; 2: S1-16.
23. Cai L, Xue H, Lu H, Zhao Y, Zhu X, Bu D, Ling L, Chen R: Analysis of correlations between protein complex and protein-protein interaction and mRNA expression. Chinese Sci Bull 2003; 48: 2226-2230.
24. Yunku Yeu J, Youngmi Y, Sanghyun P: Protein complex discovery from protein interaction network with high false-positive rate. Lect Notes Comput Sci 2011; 6623: 177-182.
25. American Cancer Society 2011: Cancer Facts and Figures 2011, 2011.
26. Wallace JD, Levy LL: Blood pressure after stroke. JAMA 1981; 246: 2177-2180.
27. Hachinski V: Hypertension in acute ischemic strokes. Arch Neurol 1985; 42: 1002.
28. Thomas MC, MacIsaac RJ, Tsalamandris C, Power D, Jerums G: Unrecognized anemia in patients with diabetes: a cross-sectional survey. Diabetes Care 2003; 26: 1164-1169.
29. Mulligan HD, Beck SA, Tisdale MJ: Lipid metabolism in cancer cachexia. Br J Cancer 1992; 66: 57-61.
30. Shaw RJ: Glucose metabolism and cancer. Curr Opin Cell Biol 2006; 18: 598-608.
31. Cottier H, Hess MW, Walti ER: Immunodeficiency and cancer: mechanisms involved. Schweiz Med Wochenschr 1986; 116: 1119-1126.
32. Hadden JW: Immunodeficiency and cancer: prospects for correction. Int Immuno-pharmacol 2003; 3: 1061-1071.