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Volumn 60, Issue 4, 2012, Pages 323-334

Clofibrate PPARα activation reduces oxidative stress and improves ultrastructure and ventricular hemodynamics in no-flow myocardial ischemia

Author keywords

angiotensin (1 7); angiotensin II; nitric oxide; superoxide dismutase

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN[1-7]; CATALASE; CLOFIBRATE; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; REACTIVE OXYGEN METABOLITE; TETRAHYDROBIOPTERIN;

EID: 84867740420     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e31826216ed     Document Type: Article
Times cited : (47)

References (59)
  • 1
    • 0036773047 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart
    • Finck BN, Kelly DP. Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart. J Mol Cell Cardiol. 2002;34: 1249-1257.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1249-1257
    • Finck, B.N.1    Kelly, D.P.2
  • 2
    • 1242329357 scopus 로고    scopus 로고
    • Oxidative stressinduced ischemic heart disease: Protection by antioxidants
    • Bandyopadhyay D, Chattopadhyay A, Ghosh G, et al. Oxidative stressinduced ischemic heart disease: protection by antioxidants. Curr Med Chem. 2004;11:369-387.
    • (2004) Curr Med Chem , vol.11 , pp. 369-387
    • Bandyopadhyay, D.1    Chattopadhyay, A.2    Ghosh, G.3
  • 3
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev. 2007;87:315-424.
    • (2007) Physiol Rev , vol.87 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 4
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol Rev. 2002;82:47-52.
    • (2002) Physiol Rev , vol.82 , pp. 47-52
    • Droge, W.1
  • 5
    • 0033046052 scopus 로고    scopus 로고
    • Signal transduction by reactive oxygen species in non phagocytic cells
    • Finkel T. Signal transduction by reactive oxygen species in non phagocytic cells. J Leukoc Biol. 1999;65:337-340.
    • (1999) J Leukoc Biol , vol.65 , pp. 337-340
    • Finkel, T.1
  • 6
    • 0036089571 scopus 로고    scopus 로고
    • Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of the heart failure
    • Sorescu D, Griendling KK. Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of the heart failure. Congest Heart Fail. 2002;8:132-140.
    • (2002) Congest Heart Fail , vol.8 , pp. 132-140
    • Sorescu, D.1    Griendling, K.K.2
  • 7
    • 0030754792 scopus 로고    scopus 로고
    • Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction
    • Hill MF, Signal PK. Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction. Circulation. 1997;96:2414-2420.
    • (1997) Circulation , vol.96 , pp. 2414-2420
    • Hill, M.F.1    Signal, P.K.2
  • 8
    • 8444232777 scopus 로고    scopus 로고
    • Oxidative stress in the infarcted heart: Role of de novo angiotensin II production
    • Lu L, Quinn MT, Sun Y. Oxidative stress in the infarcted heart: role of de novo angiotensin II production. Biochem Biophys Res Commun. 2004; 325:943-951.
    • (2004) Biochem Biophys Res Commun , vol.325 , pp. 943-951
    • Lu, L.1    Quinn, M.T.2    Sun, Y.3
  • 9
    • 0028839103 scopus 로고
    • Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarction
    • Nio Y, Matsubara H, Murasawa S, et al. Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarction. J Clin Invest. 1995;95:46-54.
    • (1995) J Clin Invest , vol.95 , pp. 46-54
    • Nio, Y.1    Matsubara, H.2    Murasawa, S.3
  • 11
    • 0034467428 scopus 로고    scopus 로고
    • PPAR signaling in the control of cardiac energy metabolism
    • Barger PM, Kelly DP. PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med. 2000;10:238-245.
    • (2000) Trends Cardiovasc Med , vol.10 , pp. 238-245
    • Barger, P.M.1    Kelly, D.P.2
  • 12
    • 73649131915 scopus 로고    scopus 로고
    • PPARa stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner
    • Ibarra-Lara L, Cervantes-Pérez LG, Pérez-Severiano F, et al. PPARa stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner. Eur J Pharmacol. 2010;627: 185-193.
    • (2010) Eur J Pharmacol , vol.627 , pp. 185-193
    • Ibarra-Lara, L.1    Cervantes-Pérez, L.G.2    Pérez-Severiano, F.3
  • 13
    • 0030030304 scopus 로고    scopus 로고
    • Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats
    • Hill MF, Singal PK. Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats. Am J Pathol. 1996;148:291-300.
    • (1996) Am J Pathol , vol.148 , pp. 291-300
    • Hill, M.F.1    Singal, P.K.2
  • 14
    • 84867745046 scopus 로고    scopus 로고
    • The isolated perfused heart according to Langendorff
    • Biomesstechnik-Verlag
    • Doring H, Dehnert H. The isolated perfused heart according to Langendorff. Friburgo de Brisgovi, Biomesstechnik-Verlag. 1998;45:1-70.
    • (1998) Friburgo de Brisgovi , vol.45 , pp. 1-70
    • Doring, H.1    Dehnert, H.2
  • 15
    • 0025087596 scopus 로고
    • Sensitive and rapid quantitation of oxygen reactive species in rat synaptosomes
    • LeBel CP, Bondy CP. Sensitive and rapid quantitation of oxygen reactive species in rat synaptosomes. Neurochem Int. 1990;17:435-440.
    • (1990) Neurochem Int , vol.17 , pp. 435-440
    • Lebel, C.P.1    Bondy, C.P.2
  • 16
    • 0024402834 scopus 로고
    • An assay for superoxide dismutase activity in mammalian tissue homogenates
    • Spitz DR, Oberley LW. An assay for superoxide dismutase activity in mammalian tissue homogenates. Anal Biochem. 1989;179:8-18.
    • (1989) Anal Biochem , vol.179 , pp. 8-18
    • Spitz, D.R.1    Oberley, L.W.2
  • 17
  • 18
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121-126.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 19
    • 0031981718 scopus 로고    scopus 로고
    • The role of nitric oxide in angiotensin II-induced renal vasoconstriction in renovascular hypertension
    • Sánchez-Mendoza A, Hong E, Escalante B. The role of nitric oxide in angiotensin II-induced renal vasoconstriction in renovascular hypertension. J Hypertens. 1998;16:697-703.
    • (1998) J Hypertens , vol.16 , pp. 697-703
    • Sánchez-Mendoza, A.1    Hong, E.2    Escalante, B.3
  • 20
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • Lowry OH, Rosebrough WJ, Farr AL, et al. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, W.J.2    Farr, A.L.3
  • 21
    • 0037178634 scopus 로고    scopus 로고
    • Nitric oxide and nitric oxide synthases in fetal cerebral cortex of rats following transient uteroplacental ischemia
    • González-Barrios JA, Escalante B, Valdés J, et al. Nitric oxide and nitric oxide synthases in fetal cerebral cortex of rats following transient uteroplacental ischemia. Brain Res. 2002;945:114-122.
    • (2002) Brain Res , vol.945 , pp. 114-122
    • González-Barrios, J.A.1    Escalante, B.2    Valdés, J.3
  • 22
    • 0026764084 scopus 로고
    • Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase
    • Janssens SP, Shimouchi T, Quertermous T, et al. Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase. J Biol Chem. 1992;267:14519-14522.
    • (1992) J Biol Chem , vol.267 , pp. 14519-14522
    • Janssens, S.P.1    Shimouchi, T.2    Quertermous, T.3
  • 23
    • 24144432114 scopus 로고    scopus 로고
    • Total antioxidant capacity assay of human serum using copper(II)-neocuproine as chromogenic oxidant: The CUPRAC method
    • Apak R, Guclu K, Ozyurek M. Total antioxidant capacity assay of human serum using copper(II)-neocuproine as chromogenic oxidant: the CUPRAC method. Free Radic Res. 2005;39:949-961.
    • (2005) Free Radic Res , vol.39 , pp. 949-961
    • Apak, R.1    Guclu, K.2    Ozyurek, M.3
  • 24
    • 84875581978 scopus 로고    scopus 로고
    • The ferric reducing power (FRP). An assay for the serum antioxidant capacity assessment
    • Bahr VP, Basulto LY. The ferric reducing power (FRP). An assay for the serum antioxidant capacity assessment. Correo Científico Médico de Holguín. 2004;8:1-8.
    • (2004) Correo Científico Médico de Holguín , vol.8 , pp. 1-8
    • Bahr, V.P.1    Basulto, L.Y.2
  • 25
    • 0033804978 scopus 로고    scopus 로고
    • Detection of neuropeptides using on-capillary copper complexation and capillary electrophoresis with electrochemical detection
    • Gawron AJ, Lunte SM. Detection of neuropeptides using on-capillary copper complexation and capillary electrophoresis with electrochemical detection. Electrophoresis. 2000;21:3205-3211.
    • (2000) Electrophoresis , vol.21 , pp. 3205-3211
    • Gawron, A.J.1    Lunte, S.M.2
  • 26
    • 77954860411 scopus 로고    scopus 로고
    • Histological and stereological studies on Leydig cells in the testes of Gallus domesticus from prehatching to sexual maturity
    • González-Morán MG, Soria-Castro E. Histological and stereological studies on Leydig cells in the testes of Gallus domesticus from prehatching to sexual maturity. Anim Reprod Sci. 2010;120:129-135.
    • (2010) Anim Reprod Sci , vol.120 , pp. 129-135
    • González-Morán, M.G.1    Soria-Castro, E.2
  • 27
    • 77952484425 scopus 로고    scopus 로고
    • Changes in the tubular compartment of testis of Gallus domesticus during development
    • González-Morán MG, Soria-Castro E. Changes in the tubular compartment of testis of Gallus domesticus during development. Br Poult Sci. 2010;51:296-307.
    • (2010) Br Poult Sci , vol.51 , pp. 296-307
    • González-Morán, M.G.1    Soria-Castro, E.2
  • 28
    • 0027715238 scopus 로고
    • Myocardial damage during ischemia and reperfusion
    • Ferrari R, Ceconi C, Curello S, et al. Myocardial damage during ischemia and reperfusion. Eur Heart J. 1993;14(suppl G):25-30.
    • (1993) Eur Heart J , vol.14 , Issue.SUPPL. G , pp. 25-30
    • Ferrari, R.1    Ceconi, C.2    Curello, S.3
  • 29
    • 0000098037 scopus 로고
    • Direct measurement of free radical generation following reperfusion of ischemic myocardium
    • Zweier JL, Flaherty JT, Weisfeldt ML. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc Natl Acad Sci USA. 1987;84:1404-1407.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1404-1407
    • Zweier, J.L.1    Flaherty, J.T.2    Weisfeldt, M.L.3
  • 30
    • 0024308421 scopus 로고
    • Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury
    • Goldhaber JI, Ji S, Lamp ST, et al. Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury. J Clin Invest. 1989;83:1800-1809.
    • (1989) J Clin Invest , vol.83 , pp. 1800-1809
    • Goldhaber, J.I.1    Ji, S.2    Lamp, S.T.3
  • 31
    • 0032508696 scopus 로고    scopus 로고
    • Fatty acids activate transcription of the muscle carnitine palmitoyltransferase i gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha
    • Brandt JM, Djouadi F, Kelly DP. Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha. J Biol Chem. 1998;273: 23786-23792.
    • (1998) J Biol Chem , vol.273 , pp. 23786-23792
    • Brandt, J.M.1    Djouadi, F.2    Kelly, D.P.3
  • 32
    • 0036314839 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptors (PPAR-g and PPAR-a) reduce myocardial infarct size
    • Wayman NS, Hattori Y, McDonald MC, et al. Ligands of peroxisome proliferator-activated receptors (PPAR-g and PPAR-a) reduce myocardial infarct size. FASEB J. 2002;16:1027-1040.
    • (2002) FASEB J , vol.16 , pp. 1027-1040
    • Wayman, N.S.1    Hattori, Y.2    McDonald, M.C.3
  • 33
    • 33748983516 scopus 로고    scopus 로고
    • The direct antioxidative and antiinflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta
    • Toba H, Miki S, Shimizu T, et al. The direct antioxidative and antiinflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta. Eur J Pharmacol. 2006;549:124-132.
    • (2006) Eur J Pharmacol , vol.549 , pp. 124-132
    • Toba, H.1    Miki, S.2    Shimizu, T.3
  • 34
    • 27544480918 scopus 로고    scopus 로고
    • NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)a-mediated cardiovascular effects
    • Newaz M, Blanton A, Fidelis P, et al. NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)a-mediated cardiovascular effects. Mutat Res. 2005;579:163-171.
    • (2005) Mutat Res , vol.579 , pp. 163-171
    • Newaz, M.1    Blanton, A.2    Fidelis, P.3
  • 35
    • 0035180319 scopus 로고    scopus 로고
    • The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+2superoxide dismutase and decrease p22phox message expressions in primary endothelial cells
    • Inoue I, Goto S, Matsunaga T, et al. The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+2superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. Metabolism. 2001;50:3-11.
    • (2001) Metabolism , vol.50 , pp. 3-11
    • Inoue, I.1    Goto, S.2    Matsunaga, T.3
  • 36
    • 0037007055 scopus 로고    scopus 로고
    • Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats
    • Loot AE, Rocks AJ, Henning RH, et al. Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats. Circulation. 2002;105:1548-1550.
    • (2002) Circulation , vol.105 , pp. 1548-1550
    • Loot, A.E.1    Rocks, A.J.2    Henning, R.H.3
  • 37
    • 63249097505 scopus 로고    scopus 로고
    • Effects of angiotensin-(1-7) on oxidative stress and functional changes of isolated rat hearts induced by ischemia-reperfusion
    • Liao XX, Guo RX, Ma H, et al. Effects of angiotensin-(1-7) on oxidative stress and functional changes of isolated rat hearts induced by ischemia-reperfusion. Nan Fang Yi Ke Da Xue Bao. 2008;28:1345-1348.
    • (2008) Nan Fang Yi Ke da Xue Bao , vol.28 , pp. 1345-1348
    • Liao, X.X.1    Guo, R.X.2    Ma, H.3
  • 38
    • 36248993506 scopus 로고    scopus 로고
    • Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats
    • Benter IF, Yousif MH, Dhaunsi GS, et al. Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats. Am J Nephrol. 2008;28:25-33.
    • (2008) Am J Nephrol , vol.28 , pp. 25-33
    • Benter, I.F.1    Yousif, M.H.2    Dhaunsi, G.S.3
  • 39
    • 0035665449 scopus 로고    scopus 로고
    • Angiotensin receptors: Signaling, vascular pathophysiology, and interactions with ceramide
    • Berry C, Touyz R, Dominiczak AF, et al. Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide. Am J Physiol Heart Circ Physiol. 2001;281:H2337-H2365.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Berry, C.1    Touyz, R.2    Dominiczak, A.F.3
  • 40
    • 0038518483 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice
    • Adachi Y, Yoshihiko S, Kishimoto I, et al. Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice. Circulation. 2003;107:2406-2408.
    • (2003) Circulation , vol.107 , pp. 2406-2408
    • Adachi, Y.1    Yoshihiko, S.2    Kishimoto, I.3
  • 41
    • 33751344579 scopus 로고    scopus 로고
    • AT2 receptor mediates the cardioprotective effects of AT1 receptor antagonist in post-myocardial infarction remodeling
    • Oishi Y, Ozono R, Yoshizumi M, et al. AT2 receptor mediates the cardioprotective effects of AT1 receptor antagonist in post-myocardial infarction remodeling. Life Sci. 2006;80:82-88.
    • (2006) Life Sci , vol.80 , pp. 82-88
    • Oishi, Y.1    Ozono, R.2    Yoshizumi, M.3
  • 42
    • 0032482975 scopus 로고    scopus 로고
    • Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
    • Vásquez-Vivar J, Kalynaraman B, Martasek P. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA. 1998;95:9220-9225.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9220-9225
    • Vásquez-Vivar, J.1    Kalynaraman, B.2    Martasek, P.3
  • 43
    • 35448929005 scopus 로고    scopus 로고
    • Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4
    • Dumitrescu C, Biondi R, Xia Y, et al. Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4. Proc Natl Acad Sci USA. 2007;104: 15081-15086.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15081-15086
    • Dumitrescu, C.1    Biondi, R.2    Xia, Y.3
  • 44
    • 0030779819 scopus 로고    scopus 로고
    • Decreased nitric-oxide synthase activity causes impaired endothelium dependent relaxation in the postischemic heart
    • Giraldez R, Panda A, Xia Y, et al. Decreased nitric-oxide synthase activity causes impaired endothelium dependent relaxation in the postischemic heart. J Biol Chem. 1997;272:21420-21426.
    • (1997) J Biol Chem , vol.272 , pp. 21420-21426
    • Giraldez, R.1    Panda, A.2    Xia, Y.3
  • 45
    • 11144355198 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor a agonist increase nitric oxide synthase expression in vascular endothelial cells
    • Goya K, Sumitani S, Xu X, et al. Peroxisome proliferator-activated receptor a agonist increase nitric oxide synthase expression in vascular endothelial cells. Arterioscler Thromb Vasc Biol. 2004;24:658-663.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 658-663
    • Goya, K.1    Sumitani, S.2    Xu, X.3
  • 46
    • 0029031437 scopus 로고
    • Nitric oxide regulates coronary blood flow at various coronary arterial pressures in intact porcine hearts
    • Offstad P, Naess PA, Aksnes G. Nitric oxide regulates coronary blood flow at various coronary arterial pressures in intact porcine hearts. Acta Physiol Scand. 1995;154:93-102.
    • (1995) Acta Physiol Scand , vol.154 , pp. 93-102
    • Offstad, P.1    Naess, P.A.2    Aksnes, G.3
  • 47
    • 0027250717 scopus 로고
    • Modulation of coronary autoregulatory responses by nitric oxide. Evidence for flow-dependent resistance adjustments in conscious dogs
    • Smith TP, Canty JM. Modulation of coronary autoregulatory responses by nitric oxide. Evidence for flow-dependent resistance adjustments in conscious dogs. Cir Res. 1993;73:232-240.
    • (1993) Cir Res , vol.73 , pp. 232-240
    • Smith, T.P.1    Canty, J.M.2
  • 48
    • 33645734144 scopus 로고    scopus 로고
    • Protection against myocardial ischaemia/reperfusion injury by PPAR-alpha activation is related to production of nitric oxide and endothelin-1
    • Bulhak AA, Sjoquist PO, Xu CB, et al. Protection against myocardial ischaemia/reperfusion injury by PPAR-alpha activation is related to production of nitric oxide and endothelin-1. Basic Res Cardiol. 2006;101: 244-252.
    • (2006) Basic Res Cardiol , vol.101 , pp. 244-252
    • Bulhak, A.A.1    Sjoquist, P.O.2    Xu, C.B.3
  • 49
    • 33745567557 scopus 로고    scopus 로고
    • Effects of bezafibrate on the expression of endothelial nitric oxide synthase gene and its mechanisms in cultured bovine endothelial cells
    • Wang Y, Wang Y, Yang Q, et al. Effects of bezafibrate on the expression of endothelial nitric oxide synthase gene and its mechanisms in cultured bovine endothelial cells. Atherosclerosis. 2006;187: 265-273.
    • (2006) Atherosclerosis , vol.187 , pp. 265-273
    • Wang, Y.1    Wang, Y.2    Yang, Q.3
  • 50
    • 34547882896 scopus 로고    scopus 로고
    • Efectos del óxido nítrico sobre la función cardiaca
    • Tamargo J, Caballero R, Gómez R, et al. Efectos del óxido nítrico sobre la función cardiaca. Rev Esp Cardiol. 2006;6(suppl A):3A-20A.
    • (2006) Rev Esp Cardiol , vol.6 , Issue.SUPPL. A
    • Tamargo, J.1    Caballero, R.2    Gómez, R.3
  • 51
    • 0036081380 scopus 로고    scopus 로고
    • Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II
    • Wang HD, Johns DG, Xu S, et al. Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II. Am J Physiol. 2002;282:H1697-H1702.
    • (2002) Am J Physiol , vol.282
    • Wang, H.D.1    Johns, D.G.2    Xu, S.3
  • 52
    • 0029037495 scopus 로고
    • The chemistry of peroxinitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor WA, Squadrito GL. The chemistry of peroxinitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol. 1995;268(5 Pt 1): L699-L722.
    • (1995) Am J Physiol , vol.268 , Issue.5 PART 1
    • Pryor, W.A.1    Squadrito, G.L.2
  • 53
    • 0343024079 scopus 로고
    • The role of catalase as a defense mechanism against reperfusion injury
    • Abstract
    • Iwata T, Konno N, Yanagishita T, et al. The role of catalase as a defense mechanism against reperfusion injury. J Mol Cell Cardiol. 1993;25(suppl 1):S104. Abstract.
    • (1993) J Mol Cell Cardiol , vol.25 , Issue.SUPPL. 1
    • Iwata, T.1    Konno, N.2    Yanagishita, T.3
  • 54
    • 0033799773 scopus 로고    scopus 로고
    • PPARa: A key to the mechanism of hepatoprotection by clofibrate
    • Mehendale H. PPARa: a key to the mechanism of hepatoprotection by clofibrate. Toxicol Sci. 2000;57:187-190.
    • (2000) Toxicol Sci , vol.57 , pp. 187-190
    • Mehendale, H.1
  • 55
    • 5144224821 scopus 로고    scopus 로고
    • PPARa ligands activat antioxidant enzymes and suppress hepatic fibrosis in rats
    • Toyama T, Nakamura H, Harano Y, et al. PPARa ligands activat antioxidant enzymes and suppress hepatic fibrosis in rats. Biochem Biophys Res Commun. 2004;324:697-704.
    • (2004) Biochem Biophys Res Commun , vol.324 , pp. 697-704
    • Toyama, T.1    Nakamura, H.2    Harano, Y.3
  • 56
    • 0031009490 scopus 로고    scopus 로고
    • Peroxynitrite, the product of nitric oxide and superoxide, causes myocardial injury in the isolated perfused rat heart
    • López BL, Liu GL, Christopher TA, et al. Peroxynitrite, the product of nitric oxide and superoxide, causes myocardial injury in the isolated perfused rat heart. Coron Artery Dis. 1997;8:149-153.
    • (1997) Coron Artery Dis , vol.8 , pp. 149-153
    • López, B.L.1    Liu, G.L.2    Christopher, T.A.3
  • 57
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
    • Radi R, Beckman JS, Bush KM, et al. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys. 1991;288:481-487.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3
  • 58
    • 0034683031 scopus 로고    scopus 로고
    • Status of myocardial antioxidants in ischemia-reperfusion injury
    • Dhalla N, Elmoselhi A, Hata T, et al. Status of myocardial antioxidants in ischemia-reperfusion injury. Cardiovasc Res. 2000;47: 446-456.
    • (2000) Cardiovasc Res , vol.47 , pp. 446-456
    • Dhalla, N.1    Elmoselhi, A.2    Hata, T.3
  • 59
    • 60449118491 scopus 로고    scopus 로고
    • Pathophysiology of ischemia-reperfusion injury: New therapeutic options for acute myocardial infarction
    • Ruiz Meana M, García-Dorado D. Pathophysiology of ischemia-reperfusion injury: new therapeutic options for acute myocardial infarction. Rev Esp Cardiol. 2009;62:199-209.
    • (2009) Rev Esp Cardiol , vol.62 , pp. 199-209
    • Ruiz Meana, M.1    García-Dorado, D.2


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