Global DNA methylation not increased in chronic hemodialysis patients: A case-Control study

Renal Failure

Volumn 34, Issue 10, 2012, Pages 1195-1199

  Hsu, Chiao Ying ^a,b   Sun, Chiao Yin ^a,b   Lee, Chin Chan ^a,b   Wu, I Wen ^a,b   Hsu, Heng Jung ^a,b   Wu, Mai Szu ^c,d  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

DNA methylation; Homocysteine; Indoxyl sulfate; p cresol sulfate; Uremia

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; CREATININE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; HOMOCYSTEINE; INDICAN; INDOXYL SULPHATE; MESSENGER RNA; P CRESOL SULFATE; PARATHYROID HORMONE; SULFATE; UNCLASSIFIED DRUG; URIC ACID;

ADULT; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA METHYLATION; FEMALE; HEMODIALYSIS PATIENT; HUMAN; LEUKOCYTE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UREA NITROGEN BLOOD LEVEL; UREMIA;

CASE-CONTROL STUDIES; DNA METHYLATION; DNA MODIFICATION METHYLASES; FEMALE; HUMANS; MALE; MIDDLE AGED; RENAL DIALYSIS; UREMIA;

EID: 84867737739     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2012.723280     Document Type: Article

References (21)

1. Hwang SJ, Tsai JC, Chen HC. Epidemiology, impact and preventive care of chronic kidney disease in Taiwan. Nephrology. 2010;15(Suppl 2):3-"9.
2. Yavuz A, Tetta C, Ersoy FF, et al. Uremic toxins: A new focus on an old subject. Semin Dial. 2005;18:203-"211. (Pubitemid 40847278)
3. Ayodele OE, Alebiosu CO. Burden of chronic kidney disease: An international perspective. Adv Chronic Kidney Dis. 2010; 17:215-"224.
4. Murr R. Interplay between different epigenetic modifications and mechanisms. Adv Genet. 2010;70:101-"141.
5. van Vliet J, Oates NA, Whitelaw E. Epigenetic mechanisms in the context of complex diseases. Cell Mol Life Sci. 2007; 64:1531-"1538. (Pubitemid 46954151)
6. Calvanese V, Lara E, Kahn A, FragaMF. The role of epigenetics in aging and age-related diseases. Aging Res Rev. 2009;8:268-"276.
7. Turek-Plewa J, Jagodzi-nski PP. The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell Mol Biol Lett. 2005;10:631-"647. (Pubitemid 43161688)
8. Fandy TE. Development of DNA methyltransferase inhibitors for the treatment of neoplastic diseases. Curr Med Chem. 2009;16:2075-"2085.
9. Pan Y, Sawalha AH. Epigenetic regulation and the pathogenesis of systemic lupus erythematosus. Transl Res. 2009;153:4-"10.
10. Ingrosso D, Cimmino A, Perna AF, et al. Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinemia in patients with uremia. Lancet. 2003;361:1693-"1699. (Pubitemid 36577442)
11. Ingrosso D, Perna AF. Epigenetics in hyperhomocysteinemic states. A special focus on uremia. Biochim Biophys Acta. 2009;1790:892-"899.
12. Castro R, Rivera I, Struys EA, et al. Increased homocysteine and S-Adenosylhomocysteine concentrations and DNA hypomethylation in vascular disease. Clin Chem. 2003;49:1292-"1296. (Pubitemid 36900615)
13. Nanayakkara PW, Kiefte-de Jong JC, Stehouwer CD, et al. Association between global leukocyte DNA methylation, renal function, carotid intima-media thickness and plasma homocysteine in patients with stage 2-"4 chronic kidney disease. Nephrol Dial Transplant. 2008;23:2586-"2592.
14. Stenvinkel P, Karimi M, Johansson S, et al. Impact of inflammation on epigenetic DNA methylation-A novel risk factor for cardiovascular disease? J Intern Med. 2007;261:488-"499. (Pubitemid 46587721)
15. Wu IW, Hsu KH, Lee CC, p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease. Nephrol Dial Transplant. 2011;26:938-"947.
16. Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Rosa-Leyva M, Vilardell-Tarrés M. Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4 T cells from patients with systemic lupus erythematosus. Immunology. 2008;124:339-"347. (Pubitemid 351793466)
17. Zhao M, Gao F, Wu X, Tang J, Lu Q. Abnormal DNA methylation in peripheral blood mononuclear cells from patients with vitiligo. Br J Dermatol. 2010;163:736-"742.
18. Hodge DR, Xiao W, Clausen PA, et al. Interleukin-6 regulation of the human DNA metyltransferase (HDNMT) gene in human erythroleukemia cells. J Biol Chem. 2001;276: 39508-"39511.
19. Montes de Oca A, Madueño JA, Martinez-Moreno JM, et al. High-phosphate-induced calcification is related to SM22α promoter methylation in vascular smooth muscle cells. J Bone Miner Res. 2010;25:1996-"2005.
20. Kaye M. The anemia associated with renal disease. J Lab Clin Med. 1958;52:83-"100.
21. Ting AH, Jair KW, Schuebel KE, Baylin SB. Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation. Cancer Res. 2006;66:729-"735. (Pubitemid 43165935)