Radioprotective effect of alcoholic extract of Mentha piperita (Linn.) on swiss albino mice exposed to whole body gamma irradiation: A preliminary study

International Journal of Pharma and Bio Sciences

Volumn 3, Issue 3, 2012, Pages

  Kaushik, Pallavi ^a   Mathur, Megha ^a   Rawat, Neha ^a   Dutt, Punar ^b  

^a IIS UNIVERSITY   (India)

^b Government College   (India)

Author keywords

Dose reduction factor; Mentha piperita; Morbidity; Radioprotective

Indexed keywords

GLUTATHIONE; LIPID; PEPPERMINT;

ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; CHEMICAL ANALYSIS; COBALT TELETHERAPY; CONTROLLED STUDY; DIARRHEA; DRUG ACTIVITY; DRUG DOSE REDUCTION; DRUG TOLERABILITY; FACE EDEMA; FEMALE; GAMMA RADIATION; HAIR DISEASE; IONIZING RADIATION; LD 50; LETHARGY; LIPID OXIDATION; MEDICINAL PLANT; MENTHA PIPERITA; MORTALITY; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; RADIATION EXPOSURE; RADIATION PROTECTION; RADIATION SICKNESS; SURVIVAL; WEIGHT REDUCTION; WHOLE BODY RADIATION;

EID: 84867706602     PISSN: None     EISSN: 09756299     Source Type: Journal    
DOI: None     Document Type: Article

References (70)

1. Sweeney TR, A Survey of compounds from the antiradiation Drug development Program of the U.S. Army Medical Research Development Command. Walter Reed Army Institute of Research, Washington, DC: 1-851, (1979).
2. Weiss JF and Landauer MR, Protection against ionizing radiation by antioxidant nutrients and Phytochemicals. Toxicology.189: 1-20, (2003).
3. Rastogi RP and Mehrotra BN, Ed. Compendium of Indian Medicinal Plants. Vol. 3. CDRI & PID: New Delhi. 420-422, (1991).
4. Krishnaswamy K and Raghuramulu N, Bioactive Phytochemicals with emphasis on dietary practices. Indian J. Med. Res. 108: 167-181, (1988).
5. Al-Sereiti MR, Abu-Amer KM, Sen P, Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potential. Indian. J. Exp. Biol. 37: 124-130, (1999).
6. Mimica-Dukic N, Bozin B, Sokovic M, Mihajlovic B and Matavulj M, Antimicrobial and antioxidant activities of three Mentha species essential oils. Planta. Med.69(5): 413-419, (2003).
7. Ortmann EK., Mayerhofer T, Getoff N and Kodym R, Effect of Antioxidant vitamins on radiation induced apoptosis in cells of a human lymphoblasic cell line. Radiat. Res. 161: 48-55, (2004).
8. Inoue T, Sugimoto Y, Masuda H, Kamei C, Anti-allergic effect of flavonoid glycosides obtained from Mentha piperita. L. Biol. Pharm. Bull.25(2): 256-259, (2002).
9. Samarth RM, Panwar M, Kumar M., and Kumar A, Protective effects of Mentha piperita Linn on benzo[a]pyrene-induced lung carcinogenicity and mutagenicity in Swiss albino mice. Mutagenesis, 21(1): 61-6, (2006).
10. Schuhmacher A, Reichling J and Schnitzler P, Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type -1 and type-2 in vitro. Phytomedicine. 10(6-7): 504-10, (2003).
11. Edris AE and Farrag ES, Antifungal activity of peppermint oil and sweet basil essential oils their major aroma constituents on some plant pathogenic fungi. Nahrung. 47(2): 117-121, (2003).
12. Kumar A, Samarth RM, Yasmeen S, Sharma A, Sugahara T, Terado T, Kimura H, Anticancer and radioprotective potentials of Mentha piperita. Biofactors. 22(1-4): 87-91, (2004).
13. Jain D, Pathak N, Khan S, Raghuram GV, Bhargava A, Samarth R, Mishra PK, Evaluation of cytotoxicity and anticarcinogenic potential of Mentha leaf extracts. Int J. Toxicol. 30(2): 225-236, (2011).
14. Sharafi SM, Rasooli I, Owlia P, Taghizadeh M and Astaneh SD, Protective effects of bioactive phytochemicals from Mentha piperita with multiple health potentials. Pharmacogn Mag.6(23): 147-153, (2010).
15. Samarth RM, Saini MR, Maharwal J, Dhaka A and Kumar A, Mentha piperita (Linn) leaf extract provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice. Indian J. Exp. Biol. 40(11):1245-1249, (2002).
16. Samarth RM, Goyal PK, Kumar A, Protection of swiss albino mice against whole-body gamma irradiation by Mentha piperita (Linn.). Phytother. Res. 18(7): 546-550, (2004).
17. Moron MS, Depierre JW and Mannervik B, Levels of GSH, GR and GST activities in rat lung and liver. Biochem. Biophys. Acta.582: 67-78, (1979).
18. Ohkhawa H, Ohishi N and Yogi K, Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal. Biochem. 95: 351-358, (1979).
19. rd Edn, Blackwell Scientific Publication, Oxford. (1985).
20. Uma Devi P, Ganasoundari A, Rao BSS and Srinivasan KK, In vivo radioprotection by Ocimum flavonoids: Survival of mice. Radiat. Res., 151: 74-78, (1999).
21. Samarth RM, Modulation of radiation induced alterations in Swiss albino mice by plant extract. A Ph. D. Thesis, University of Rajasthan Jaipur, India (2001).
22. Jagetia GC, Venkatesh P, Baliga MS, Fruit extract of Aeglemarmelos protects mice against radiation-induced lethality. Integr. Cancer Ther. 3(4): 323-332, (2004).
23. Jagetia GC and Baliga MS, Polyherbal extract of septilin protects mice against whole body lethal dose of gamma radiation. Phytother. Res. 18: 619-623, (2004a).
24. Warren L and Whipple GH, Roentgen ray intoxication. II. A study of sequence of clinical anatomical and histological changes following a unit dose of X-ray. J. Exp. Med. 35: 203, (1922).
25. Naruka K, Study of the radioprotective effect of WR-2721 on bone marrow and spleen of Swiss albino mice. A Ph. D. Thesis, University of Rajasthan, Jaipur. India, (1986).
26. Daga SS, Haematological response against the combined use of mercury and radiation in mice and its alteration by Liv. 52. A Ph. D. Thesis, University of Rajasthan, Jaipur, India, (1996).
27. Sullivan MF, Radiation diarrhoea modified by diverting the bile flow from the gastrointestinal tract. In "Radiation effects in physics, chemistry and biology". Albert, M. and Howard, A (Eds.), North Holland Co., Amsterdam: 450, (1963).
28. Gits J and Gerber GB, Electrolyte loss the main cause of death from gastrointestinal syndrome. Radiat. Res. 15: 18, (1973).
29. Duncan W and Leonard JC, The malabsorption syndrome following radiotherapy. Q.J. Med. 34(135): 319-329, (1965).
30. Berk RN and Seay DG, Cholerheicenteropathy as a cause of diarrhea and death in radiation enteritis and its prevention with cholestyranus. Radiobiology. 104: 153-156, (1972).
31. Fajardo LF, Berthrong M and Anderson RE, Small intestine In "Radiation pathology" Oxford University Press. 228, (2001).
32. Chi C, Ozawa T and Anzai K, In vivo nitric oxide production and iNOS expression in Xray irradiated mouse skin. Biol. Pharm. Bull. 29(2): 348-53, (2006).
33. Smith WW, Ackermann IB and Smith F, Body weight and forced feeding after whole-body x-irradiation. Am. J. Physiol. 168: 325-390, (1952).
34. Quastler H, The nature of intestinal radiation death. Radiat. Res. 4: 303-320, (1956).
35. Nakamura W, Kojima E, Minamizawa H, Kankura T, Kabayashi S and Eto H, In "Comparative cellular and species radiosensitivity in animals". Bond, V.P. and Sugahara, T. (Eds.) lgakuShoin, Tokyo, (1968).
36. Dublineau I, Lebrum F and Griffiths NM, Effects of gamma radiation on rat colonic water and electrolyte flux. Proc. Int. Cong. Radiat. Res. Germany: 261, (1995).
37. Griffiths NM, Dublineau I, Francois A and Ksas B, Radiation induced colonic injury: Decreased fluid absorption and effects of granisetronA 5HT3 receptor inhibitor. In "Adv. Rad. Biol. and Peace." (Suppl. II) Goel, S.C. (Ed.), Uttar Pradesh Zoological Society, Muzaffarnagar, India, (1999).
38. Kumar A and Uma Devi P, Chemical protection of mice against radiation induced sickness and mortality by- 2-MPG. Radiobiol. Radiother. 24: 231 (1983).
39. Bond VP, Fliedner TM and Archambeau JO, In "Mammalian Radiation lethality". A disturbance in Cellular kinetics. Academic press, N.Y. London, (1965).
40. Jagetia GC and Baliga MS, Influence of the leaf extract of Mentha arvensis Linn. (Mint) on the survival of mice exposed to different doses of γ-radiation. Strahlentherapie und Onkologie, 2: 91-98, (2002a).
41. Jagetia GC, Baliga SM, Malagi KJ and Kamath MS, The evaluation of the radioprotective effect of triphala (an ayurvedic rejuvenating drug) in the mice exposed to γ-radiation. Phytomedicine. 9: 99-108, (2002).
42. Jagetia GC and Baliga MS, Syzygiumcumini (Jamun) reduces the radiation-induced DNA damage in the cultured human peripheral blood lymphocytes: a preliminary study. Toxicol. Lett. 132(1): 19-25, (2002b).
43. Chrom, Studies on the effect of Roentgen -rays upon the intestinal epithelium and upon the reticuloendothelial cells of the liver and spleen. ActaRadiol. 16: 641, (1935).
44. Miller CP, Hammond CW and Tompkins M, The incidence of bacteremia in mice subjected to total body X-irradiation. Science. 111: 540, (1950).
45. Miller CP, Hammond CW and Tompkins M, The role of infection in radiation injury. J. Lab. Clin. Med. 88: 331, (1951).
46. Brook I and Elliott TB, Quinolone therapy in the prevention of mortality after irradiation. Radiat. Res. 128: 100, (1991).
47. Tate S, Peppermint oil: a treatment for postoperative nausea. J. Adv. Nurs. 26(3): 543-9, (1997).
48. Westfall RE, Use of anti-emetic herbs in pregnancy: women's choice and the question of safety and efficacy. complement. Ther. Nurs. Midwifery. 10(1): 30-36, (2004).
49. Heimes K, Hauk F and Verspohl EJ, Mode of action of peppermint oil and (-)- menthol with respect to 5-HT3 receptor subtypes: binding studies, cation uptake by receptor channels and contraction of isolated rat ileum. Phytother Res. 25(5): 702-708, (2011).
50. Beesley A, Hardcastle J, Hardcastle PT and Taylor CJ, Influence of peppermint oil on absorptive and secretory processes in rat small intestine. Gut. 39: 214-219, (1996).
51. Mckay DL and Blumberg JB, A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). Phytother Res.20(8): 619-633, (2006).
52. Iscan G, Kirimer N, Kuskcuogle H, Can Baser K and Demerci F, Antimicrobial Screening of Mentha piperita essential oils. J. Agric. Food Chem. 50(14): 3943-3946, (2002).
53. Keinan E, Alt A, Amir G, Bentur L, Bibi H and Shoseyov D, Natural ozone Scavanger, prevents asthama in sensitized rats. Bioorg. Med. Chem. 13(2): 557-562, (2005).
54. MahmoudSS, Williams M, Croteau, R, Cosuppression of limonene-3-hydroxylase in peppermint promotes accumulation of limonene in the essential oil. Phytochemistry. 65(5): 547-554, (2004).
55. Jagetia GC, Shirwaikar A, Rao SK and Bhilegaonkar PM, Evaluation of the radioprotective effect of Ageratum conyzoideslinn. extract in mice exposed to different doses of gamma radiation. J. Pharm. Pharmacol. 55(8): 1151-1158, (2003).
56. Uma Devi P, Chemical radiation protection by alpha mercaptopropionyl glycine. J. Nucl. Med. All. Sci. 72: 327-336, (1983).
57. Jagetia GC and Baliga MS, Treatment of mice with a herbal preparation (mentat) protects against radiation - induced mortality. Phytother. Res. 17(8): 876-881, (2003).
58. Samarth RM and Kumar A, Radioprotection of Swiss Albino mice by plant extract Mentha piperita (Linn). J. Radiat. Res. 44: 101-109, (2003).
59. Jagetia GC and Baliga MS, Polyherbal extract of septilin protects mice against whole body lethal dose of gamma radiation. Phytother. Res. 18: 619-623, (2004a).
60. Jagetia GC and Baliga MS, The evaluation of the radioprotective effect of chyavanaprasha (an AyurvedicRasayanaDrug) in mice exposed to lethal dose of γ-radiation: a preliminary study. Phytother. Res. 18: 14-18, (2004b).
61. Jagetia GC and Ganapathi NG, Inhibition of clastogenic effect of radiation by Liv. 52 in the bone marrow of mice. Mutat. Res. 224: 507-510, (1989).
62. Jagetia GC and Ganapathi NG, Treatment of mice with a herbal preparation (Liv. 52) reduces the frequency of radiation induced chromosome damage in bone marrow. Mutat. Res. 253: 123-126, (1991).
63. Kumar PV, Kuttan R and Kuttan G, Radioprotective effects of Rasayanas. Ind. J. Exp. Biol.34: 848-850, (1996).
64. Suresh K and Vasudevan DM, Augmentation of murine natural killer cell and antibody dependent cytotoxicity activities by Phyllanthus emblica a new immunomodulator. Ethanopharmacol. 44: 55-60, (1994).
65. Rege NN, Thatte UM and Dahanukar SA, Adaptogenic properties of six rasayanaherbs used in Ayurvedic medicine. Phytother. Res. 13: 275-291, (1999).
66. Uma Devi P, Kamath R and Rao BSS, Radioprotective effect of Phyllanthus niruri on mouse chromosome. Curr. Sci. 78: 1245-1247, (2000).
67. Sharma MK, Kumar M and Kumar A, Radiomodifying potential of Panax ginseng in liver of Swiss albino mice against gamma radiation. J. Ginseng. Res.28(2): 78-86, (2004).
68. Imai H, Osawa K, Yasuda H, Hamashima H, Arai T and Sasatu M, Inhibition by the essential oils of peppermint and spearmint on the growth of pathogenic bacteria. Microbios. 106(1): 31-39, (2001).
69. Aw TY, Cellular redox: A modulator of intestinal epithelial cell proliferation. News Physiol. Sci. 18: 201-204, (2003).
70. Townsend DM, Tew KD and Tapiero H, The importance of glutathione in human disease. Biomed. Pharmacother. 57: 145-155, (2003).