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Volumn 94, Issue 10, 2012, Pages 849-855

Hypothesis: The female excess in cranial neural tube defects reflects an epigenetic drag of the inactivating x chromosome on the molecular mechanisms of neural fold elevation

Author keywords

Anencephaly; Epigenetic; Exencephaly; Female; Neural tube defect; X chromosome

Indexed keywords

FOLIC ACID; SEX HORMONE;

EID: 84867683395     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.23036     Document Type: Article
Times cited : (41)

References (72)
  • 1
    • 0029347164 scopus 로고
    • High-frequency developmental abnormalities in p53-deficient mice
    • Armstrong JF, Kaufman MH, Harrison DJ, et al.1995.High-frequency developmental abnormalities in p53-deficient mice.Curr Biol 5:931-936.
    • (1995) Curr Biol , vol.5 , pp. 931-936
    • Armstrong, J.F.1    Kaufman, M.H.2    Harrison, D.J.3
  • 2
    • 60849118096 scopus 로고    scopus 로고
    • A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development
    • Ashe A, Morgan DK, Whitelaw NC, et al.2008.A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development.Genome Biol 9:R182.
    • (2008) Genome Biol , vol.9
    • Ashe, A.1    Morgan, D.K.2    Whitelaw, N.C.3
  • 4
    • 11844262661 scopus 로고    scopus 로고
    • Phylogenetic shadowing and computational identification of human microRNA genes
    • Berezikov E, Guryev V, van de Belt J, et al.2005.Phylogenetic shadowing and computational identification of human microRNA genes.Cell 120:21-24.
    • (2005) Cell , vol.120 , pp. 21-24
    • Berezikov, E.1    Guryev, V.2    van de Belt, J.3
  • 5
    • 42649100978 scopus 로고    scopus 로고
    • SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation
    • Blewitt ME, Gendrel AV, Pang Z, et al.2008.SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.Nat Genet 40:663-669.
    • (2008) Nat Genet , vol.40 , pp. 663-669
    • Blewitt, M.E.1    Gendrel, A.V.2    Pang, Z.3
  • 6
    • 19644376762 scopus 로고    scopus 로고
    • An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse
    • Blewitt ME, Vickaryous NK, Hemley SJ, et al.2005.An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse.Proc Natl Acad Sci U S A 102:7629-7634.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7629-7634
    • Blewitt, M.E.1    Vickaryous, N.K.2    Hemley, S.J.3
  • 7
    • 65349184462 scopus 로고    scopus 로고
    • Folic acid, methylation and neural tube closure in humans
    • Blom HJ.2009.Folic acid, methylation and neural tube closure in humans.Birth Defects Res A Clin Mol Teratol 85:295-302.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 295-302
    • Blom, H.J.1
  • 8
    • 33747588534 scopus 로고    scopus 로고
    • Neural tube defects and folate: case far from closed
    • Blom HJ, Shaw GM, den Heijer M, et al.2006.Neural tube defects and folate: case far from closed.Nat Rev Neurosci 7:724-731.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 724-731
    • Blom, H.J.1    Shaw, G.M.2    den Heijer, M.3
  • 9
    • 0022591755 scopus 로고
    • Risk factors in the prevalence of anencephalus and spina bifida in new zealand
    • Borman GB, Smith AH, Howard JK, et al.1986.Risk factors in the prevalence of anencephalus and spina bifida in new zealand.Teratology 33:221-230.
    • (1986) Teratology , vol.33 , pp. 221-230
    • Borman, G.B.1    Smith, A.H.2    Howard, J.K.3
  • 10
    • 0034190659 scopus 로고    scopus 로고
    • 5,10-methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review
    • Botto LD, Yang Q.2000.5, 10-methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review.Am J Epidemiol 151:862-877.
    • (2000) Am J Epidemiol , vol.151 , pp. 862-877
    • Botto, L.D.1    Yang, Q.2
  • 11
    • 30544451740 scopus 로고    scopus 로고
    • Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt
    • Boyanapalli M, Lahoud OB, Messiaen L, et al.2006.Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt.Biochem Biophys Res Commun 340:1200-1208.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 1200-1208
    • Boyanapalli, M.1    Lahoud, O.B.2    Messiaen, L.3
  • 12
    • 0028283289 scopus 로고
    • Female predisposition to cranial neural tube defects is not because of a difference between the sexes in the rate of embryonic growth or development during neurulation
    • Brook FA, Estibeiro JP, Copp AJ, et al.1994.Female predisposition to cranial neural tube defects is not because of a difference between the sexes in the rate of embryonic growth or development during neurulation.J Med Genet 31:383-387.
    • (1994) J Med Genet , vol.31 , pp. 383-387
    • Brook, F.A.1    Estibeiro, J.P.2    Copp, A.J.3
  • 13
    • 57449087242 scopus 로고    scopus 로고
    • The prevalence and predictors of anencephaly and spina bifida in Texas
    • Canfield MA, Marengo L, Ramadhani TA, et al.2009.The prevalence and predictors of anencephaly and spina bifida in Texas.Paediatr Perinat Epidemiol 23:41-50.
    • (2009) Paediatr Perinat Epidemiol , vol.23 , pp. 41-50
    • Canfield, M.A.1    Marengo, L.2    Ramadhani, T.A.3
  • 14
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • Carrel L, Willard HF.2005.X-inactivation profile reveals extensive variability in X-linked gene expression in females.Nature 434:400-404.
    • (2005) Nature , vol.434 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 15
    • 0016269754 scopus 로고
    • Clues to the aetiology of neural tube malformations
    • Carter CO.1974.Clues to the aetiology of neural tube malformations.Dev Med Child Neurol 16:3-15.
    • (1974) Dev Med Child Neurol , vol.16 , pp. 3-15
    • Carter, C.O.1
  • 16
    • 0032695776 scopus 로고    scopus 로고
    • Crooked tail (Cd) models human folate-responsive neural tube defects
    • Carter M, Ulrich S, Oofuji Y, et al.1999.Crooked tail (Cd) models human folate-responsive neural tube defects.Hum Molec Genet 8:2199-2204.
    • (1999) Hum Molec Genet , vol.8 , pp. 2199-2204
    • Carter, M.1    Ulrich, S.2    Oofuji, Y.3
  • 17
    • 24644493191 scopus 로고    scopus 로고
    • Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6
    • Carter M, Chen X, Slowinska B, et al. 2005. Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6. Proc Natl Acad Sci USA 102:12843-12848.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12843-12848
    • Carter, M.1    Chen, X.2    Slowinska, B.3
  • 18
    • 77954755253 scopus 로고    scopus 로고
    • Global DNA hypomethylation is associated with NTD-affected pregnancy: a case-control study
    • Chen X, Guo J, Lei Y, et al.2010.Global DNA hypomethylation is associated with NTD-affected pregnancy: a case-control study.Birth Defects Res A Clin Mol Teratol 88:575-581.
    • (2010) Birth Defects Res A Clin Mol Teratol , vol.88 , pp. 575-581
    • Chen, X.1    Guo, J.2    Lei, Y.3
  • 19
    • 38849200354 scopus 로고    scopus 로고
    • Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes
    • Chen X, Watkins R, Delot E, et al.2008.Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes.Dev Neurobiol 68:265-273.
    • (2008) Dev Neurobiol , vol.68 , pp. 265-273
    • Chen, X.1    Watkins, R.2    Delot, E.3
  • 20
    • 18444395565 scopus 로고    scopus 로고
    • Simplex PCR assay for sex determination in mice
    • Clapcote SJ, Roder JC.2005.Simplex PCR assay for sex determination in mice.Biotechniques 38:702, 704, 706.
    • (2005) Biotechniques , vol.38 , Issue.702 , pp. 704-706
    • Clapcote, S.J.1    Roder, J.C.2
  • 21
    • 0025000359 scopus 로고
    • Methionine and neural tube closure in cultured rat embryos: Morphological and biochemical analyses
    • Coelho CND, Klein NW.1990.Methionine and neural tube closure in cultured rat embryos: Morphological and biochemical analyses.Teratology 42:437-451.
    • (1990) Teratology , vol.42 , pp. 437-451
    • Coelho, C.N.D.1    Klein, N.W.2
  • 22
    • 0024553655 scopus 로고
    • Does lumbosacral spina bifida arise by failure of neural folding or by defective canalisation?
    • Copp AJ, Brook FA.1989.Does lumbosacral spina bifida arise by failure of neural folding or by defective canalisation?J Med Genet 26:160-166.
    • (1989) J Med Genet , vol.26 , pp. 160-166
    • Copp, A.J.1    Brook, F.A.2
  • 23
    • 70349318211 scopus 로고    scopus 로고
    • The impact of retrotransposons on human genome evolution
    • Cordaux R, Batzer MA.2009.The impact of retrotransposons on human genome evolution.Nat Rev Genet 10:691-703.
    • (2009) Nat Rev Genet , vol.10 , pp. 691-703
    • Cordaux, R.1    Batzer, M.A.2
  • 24
    • 55449125896 scopus 로고    scopus 로고
    • Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects
    • Deak KL, Siegel DG, George TM, et al.2008.Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects.Birth Defects Res A Clin Mol Teratol 82:662-669.
    • (2008) Birth Defects Res A Clin Mol Teratol , vol.82 , pp. 662-669
    • Deak, K.L.1    Siegel, D.G.2    George, T.M.3
  • 25
    • 2942555396 scopus 로고    scopus 로고
    • Retrotransposon-derived elements in the mammalian genome: A potential source of disease
    • Druker R, Whitelaw E.2004.Retrotransposon-derived elements in the mammalian genome: A potential source of disease.J Inherit Metab Dis 27:319-330.
    • (2004) J Inherit Metab Dis , vol.27 , pp. 319-330
    • Druker, R.1    Whitelaw, E.2
  • 26
    • 0018579776 scopus 로고
    • Neural tube defects in curly-tail mice. I. Incidence, expression and similarity to the human condition
    • Embury S, Seller MJ, Adinolfi M, et al.1979.Neural tube defects in curly-tail mice. I. Incidence, expression and similarity to the human conditionProc Roy Soc Lond Ser B: Biol Sci 206:85-94.
    • (1979) Proc Roy Soc Lond Ser B: Biol Sci , vol.206 , pp. 85-94
    • Embury, S.1    Seller, M.J.2    Adinolfi, M.3
  • 27
    • 0025341313 scopus 로고
    • Expression of a new mutation (Axd) causing axial defects in mice correlates with maternal phenotype and age
    • Essien FB, Haviland MB, Naidoff AE, et al.1990.Expression of a new mutation (Axd) causing axial defects in mice correlates with maternal phenotype and age.Teratology 42:183-194.
    • (1990) Teratology , vol.42 , pp. 183-194
    • Essien, F.B.1    Haviland, M.B.2    Naidoff, A.E.3
  • 28
    • 0017740334 scopus 로고
    • Defects of the central nervous system in Finland: I. Variations in time and space, sex distribution, and parental age
    • Granroth G, Hakama M, Saxen L, et al.1977.Defects of the central nervous system in Finland: I. Variations in time and space, sex distribution, and parental age.Br J Prev Soc Med 31:164-170.
    • (1977) Br J Prev Soc Med , vol.31 , pp. 164-170
    • Granroth, G.1    Hakama, M.2    Saxen, L.3
  • 29
    • 0023010799 scopus 로고
    • Neural tube defects, sex ratios, and X inactivation [letter]
    • Hall JG.1986.Neural tube defects, sex ratios, and X inactivation [letter].Lancet 2:1334-1335.
    • (1986) Lancet , vol.2 , pp. 1334-1335
    • Hall, J.G.1
  • 30
    • 65349175626 scopus 로고    scopus 로고
    • Insights into prevention of human neural tube defects by folic acid arising from consideration of mouse mutants
    • Harris MJ.2009.Insights into prevention of human neural tube defects by folic acid arising from consideration of mouse mutants.Birth Defects Res A Clin Mol Teratol 85:331-339.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 331-339
    • Harris, M.J.1
  • 31
    • 33947172588 scopus 로고    scopus 로고
    • Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects
    • Harris MJ, Juriloff DM.2007.Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects.Birth Defects Res A Clin Mol Teratol 79:187-210.
    • (2007) Birth Defects Res A Clin Mol Teratol , vol.79 , pp. 187-210
    • Harris, M.J.1    Juriloff, D.M.2
  • 32
    • 77955649698 scopus 로고    scopus 로고
    • An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure
    • Harris MJ, Juriloff DM.2010.An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure.Birth Defects Res A Clin Mol Teratol 88:653-669.
    • (2010) Birth Defects Res A Clin Mol Teratol , vol.88 , pp. 653-669
    • Harris, M.J.1    Juriloff, D.M.2
  • 33
    • 0026513601 scopus 로고
    • MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin
    • Hartwig JH, Thelen M, Rosen A, et al.1992.MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin.Nature 356:618-622.
    • (1992) Nature , vol.356 , pp. 618-622
    • Hartwig, J.H.1    Thelen, M.2    Rosen, A.3
  • 34
    • 84863996715 scopus 로고    scopus 로고
    • Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus
    • Epub ahead of print].
    • Hasenpusch-Theil K, Magnani D, Amaniti EM, Han L, Armstrong D, Theil T.2012.Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus.Cereb Cortex [Epub ahead of print].
    • (2012) Cereb Cortex
    • Hasenpusch-Theil, K.1    Magnani, D.2    Amaniti, E.M.3    Han, L.4    Armstrong, D.5    Theil, T.6
  • 35
    • 0034626791 scopus 로고    scopus 로고
    • Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
    • Holmberg J, Clarke DL, Frisen J, et al.2000.Regulation of repulsion versus adhesion by different splice forms of an Eph receptor.Nature 408:203-206.
    • (2000) Nature , vol.408 , pp. 203-206
    • Holmberg, J.1    Clarke, D.L.2    Frisen, J.3
  • 36
    • 33645238760 scopus 로고    scopus 로고
    • Overlapping roles for homeodomain-interacting protein kinases Hipk1 and Hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals
    • Isono K, Nemoto K, Li Y, et al.2006.Overlapping roles for homeodomain-interacting protein kinases Hipk1 and Hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.Mol Cell Biol 26:2758-2771.
    • (2006) Mol Cell Biol , vol.26 , pp. 2758-2771
    • Isono, K.1    Nemoto, K.2    Li, Y.3
  • 37
    • 0034640007 scopus 로고    scopus 로고
    • Mouse models for neural tube closure defects
    • Juriloff DM, Harris MJ.2000.Mouse models for neural tube closure defects.Hum Mol Genet 9:993-1000.
    • (2000) Hum Mol Genet , vol.9 , pp. 993-1000
    • Juriloff, D.M.1    Harris, M.J.2
  • 38
    • 0028580680 scopus 로고
    • International study of sex ratio and twinning of neural tube defects
    • Kallen B, Cocchi G, Knudsen LB, et al.1994.International study of sex ratio and twinning of neural tube defects.Teratology 50:322-331.
    • (1994) Teratology , vol.50 , pp. 322-331
    • Kallen, B.1    Cocchi, G.2    Knudsen, L.B.3
  • 39
    • 0004348138 scopus 로고
    • Female preponderance for hereditary exencephaly in mice also exists in fetuses
    • Teratology 37: p.
    • Kalter H.1988.Female preponderance for hereditary exencephaly in mice also exists in fetuses. Teratology 37:469 p.
    • (1988) , pp. 469
    • Kalter, H.1
  • 40
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • Klose RJ, Bird AP.2006.Genomic DNA methylation: the mark and its mediators.Trends Biochem Sci 31:89-97.
    • (2006) Trends Biochem Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 41
    • 0033178548 scopus 로고    scopus 로고
    • Neurofibromin deficiency in mice causes exencephaly and is a modifier for splotch neural tube defects
    • Lakkis MM, Golden JA, O'Shea KS, et al.1999.Neurofibromin deficiency in mice causes exencephaly and is a modifier for splotch neural tube defects.Dev Biol 212:80-92.
    • (1999) Dev Biol , vol.212 , pp. 80-92
    • Lakkis, M.M.1    Golden, J.A.2    O'Shea, K.S.3
  • 42
    • 0034763128 scopus 로고    scopus 로고
    • Sex differences in the prevalence of human birth defects: a population-based study
    • Lary JM, Paulozzi LJ.2001.Sex differences in the prevalence of human birth defects: a population-based study.Teratology 64:237-251.
    • (2001) Teratology , vol.64 , pp. 237-251
    • Lary, J.M.1    Paulozzi, L.J.2
  • 43
    • 33646270883 scopus 로고    scopus 로고
    • Extremely high prevalence of neural tube defects in a 4-county area in Shanxi province, China
    • Li Z, Ren A, Zhang L, et al.2006.Extremely high prevalence of neural tube defects in a 4-county area in Shanxi province, China.Birth Defects Res A Clin Mol Teratol 76:237-240.
    • (2006) Birth Defects Res A Clin Mol Teratol , vol.76 , pp. 237-240
    • Li, Z.1    Ren, A.2    Zhang, L.3
  • 44
    • 20144383990 scopus 로고    scopus 로고
    • Sex and congenital malformations: an international perspective
    • Lisi A, Botto LD, Rittler M, et al.2005.Sex and congenital malformations: an international perspective.Am J Med Genet A 134A:49-57.
    • (2005) Am J Med Genet A , vol.134 A , pp. 49-57
    • Lisi, A.1    Botto, L.D.2    Rittler, M.3
  • 45
    • 0024539888 scopus 로고
    • Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly
    • Macdonald KB, Juriloff DM, Harris MJ.1989.Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly.Teratology 39:195-213.
    • (1989) Teratology , vol.39 , pp. 195-213
    • Macdonald, K.B.1    Juriloff, D.M.2    Harris, M.J.3
  • 46
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
    • MRC Vitamin Study Research Group... MRC Vitamin Study Research Group.: -
    • MRC Vitamin Study Research Group.1991.Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group.Lancet 338:131-137.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 47
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, et al.1999.DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.Cell 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3
  • 48
    • 0020201023 scopus 로고
    • Timing of X-chromosome inactivation in postimplantation mouse embryos
    • Rastan S.1982.Timing of X-chromosome inactivation in postimplantation mouse embryos.J Embryol Exp Morphol 71:11-24.
    • (1982) J Embryol Exp Morphol , vol.71 , pp. 11-24
    • Rastan, S.1
  • 49
    • 0012170297 scopus 로고
    • Congenital malformations of the central nervous system. I. A survey of 930 cases
    • Record RG, McKeown T.1949.Congenital malformations of the central nervous system. I. A survey of 930 cases.Brit J Soc Med 4:183-219.
    • (1949) Brit J Soc Med , vol.4 , pp. 183-219
    • Record, R.G.1    McKeown, T.2
  • 50
    • 1042278070 scopus 로고    scopus 로고
    • Sex ratio and associated risk factors for 50 congenital anomaly types: Clues for causal heterogeneity
    • Rittler M, Lopez-Camelo J, Castilla EE, et al.2004.Sex ratio and associated risk factors for 50 congenital anomaly types: Clues for causal heterogeneity.Birth Defects Res A Clin Mol Teratol 70:13-19.
    • (2004) Birth Defects Res A Clin Mol Teratol , vol.70 , pp. 13-19
    • Rittler, M.1    Lopez-Camelo, J.2    Castilla, E.E.3
  • 51
    • 15244363491 scopus 로고    scopus 로고
    • The DNA sequence of the human X chromosome
    • Ross MT, Grafham DV, Coffey AJ, et al.2005.The DNA sequence of the human X chromosome.Nature 434:325-337.
    • (2005) Nature , vol.434 , pp. 325-337
    • Ross, M.T.1    Grafham, D.V.2    Coffey, A.J.3
  • 52
    • 0029007405 scopus 로고
    • A subset of p53-deficient embryos exhibit exencephaly
    • Sah VP, Attardi LD, Mulligan GJ, et al.1995.A subset of p53-deficient embryos exhibit exencephaly.Nat Genet 10:175-180.
    • (1995) Nat Genet , vol.10 , pp. 175-180
    • Sah, V.P.1    Attardi, L.D.2    Mulligan, G.J.3
  • 53
    • 0023109677 scopus 로고
    • Neural tube defects and sex ratios
    • Seller MJ.1987.Neural tube defects and sex ratios.Am J Med Genet 26:699-707.
    • (1987) Am J Med Genet , vol.26 , pp. 699-707
    • Seller, M.J.1
  • 54
    • 0023073284 scopus 로고
    • Sex difference in mouse embryonic development at neurulation
    • Seller MJ, Perkins-Cole KJ.1987.Sex difference in mouse embryonic development at neurulation.J Reprod Fertil 79:159-161.
    • (1987) J Reprod Fertil , vol.79 , pp. 159-161
    • Seller, M.J.1    Perkins-Cole, K.J.2
  • 55
    • 0346992342 scopus 로고    scopus 로고
    • Differential risks to males and females for congenital malformations among 2.5 million California births, 1989-1997
    • Shaw GM, Carmichael SL, Kaidarova Z, et al.2003.Differential risks to males and females for congenital malformations among 2.5 million California births, 1989-1997.Birth Defects Res A Clin Mol Teratol 67:953-958.
    • (2003) Birth Defects Res A Clin Mol Teratol , vol.67 , pp. 953-958
    • Shaw, G.M.1    Carmichael, S.L.2    Kaidarova, Z.3
  • 56
    • 77952080578 scopus 로고    scopus 로고
    • A new perspective on neural tube defects: Folic acid and microRNA misexpression
    • Shookhoff JM, Gallicano GI.2010.A new perspective on neural tube defects: Folic acid and microRNA misexpression.Genesis 48:282-294.
    • (2010) Genesis , vol.48 , pp. 282-294
    • Shookhoff, J.M.1    Gallicano, G.I.2
  • 57
    • 0037967242 scopus 로고    scopus 로고
    • The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes
    • Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, et al.2003.The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.Nature 423:825-837.
    • (2003) Nature , vol.423 , pp. 825-837
    • Skaletsky, H.1    Kuroda-Kawaguchi, T.2    Minx, P.J.3
  • 58
    • 0028883213 scopus 로고
    • MARCKS deficiency in mice leads to abnormal brain development and perinatal death
    • Stumpo DJ, Bock CB, Tuttle JS, et al.1995.MARCKS deficiency in mice leads to abnormal brain development and perinatal death.Proc Natl Acad Sci USA 92:944-948.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 944-948
    • Stumpo, D.J.1    Bock, C.B.2    Tuttle, J.S.3
  • 59
    • 0027405405 scopus 로고
    • X-chromosome inactivation occurs at different times in different tissues of the post-implantation mouse embryo
    • Tan SS, Williams EA, Tam PP., et al.1993.X-chromosome inactivation occurs at different times in different tissues of the post-implantation mouse embryo.Nat Genet 3:170-174.
    • (1993) Nat Genet , vol.3 , pp. 170-174
    • Tan, S.S.1    Williams, E.A.2    Tam, P.P.3
  • 62
    • 77649201183 scopus 로고    scopus 로고
    • Gender-dependent differences in the incidence of ochratoxin A-induced neural tube defects in the Pdn/Pdn mouse
    • Ueta E, Kodama M, Sumino Y, et al.2010.Gender-dependent differences in the incidence of ochratoxin A-induced neural tube defects in the Pdn/Pdn mouse.Congenit Anom (Kyoto) 50:29-39.
    • (2010) Congenit Anom (Kyoto) , vol.50 , pp. 29-39
    • Ueta, E.1    Kodama, M.2    Sumino, Y.3
  • 63
    • 0035041246 scopus 로고    scopus 로고
    • Curly tail: a 50-year history of the mouse spina bifida model
    • van Straaten HW, Copp AJ.2001.Curly tail: a 50-year history of the mouse spina bifida model.Anat Embryol (Berl) 203:225-237.
    • (2001) Anat Embryol (Berl) , vol.203 , pp. 225-237
    • van Straaten, H.W.1    Copp, A.J.2
  • 64
    • 0027398807 scopus 로고
    • New Zealand White mice: an experimental model of exencephaly
    • Vogelweid CM, Vogt DW, Besch-Williford CL, et al.1993.New Zealand White mice: an experimental model of exencephaly.Lab Anim Sci 43:58-60.
    • (1993) Lab Anim Sci , vol.43 , pp. 58-60
    • Vogelweid, C.M.1    Vogt, D.W.2    Besch-Williford, C.L.3
  • 65
    • 0018242811 scopus 로고
    • Inheritance and morphology of exencephaly, a neonatal lethal recessive with partial penetrance, in the house mouse
    • Wallace ME, Knights PJ, Anderson JR, et al.1978.Inheritance and morphology of exencephaly, a neonatal lethal recessive with partial penetrance, in the house mouse.Genet Res 32:135-149.
    • (1978) Genet Res , vol.32 , pp. 135-149
    • Wallace, M.E.1    Knights, P.J.2    Anderson, J.R.3
  • 66
    • 77951949256 scopus 로고    scopus 로고
    • Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects
    • Wang L, Wang F, Guan J, et al.2010.Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects.Am J Clin Nutr 91:1359-1367.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1359-1367
    • Wang, L.1    Wang, F.2    Guan, J.3
  • 67
    • 77956595381 scopus 로고    scopus 로고
    • Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromnosome complement as well
    • Wijchers PJ, Yandim C, Panousopoulou E, et al.2010.Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromnosome complement as well.Dev Cell 19:477-484.
    • (2010) Dev Cell , vol.19 , pp. 477-484
    • Wijchers, P.J.1    Yandim, C.2    Panousopoulou, E.3
  • 68
    • 65649140113 scopus 로고    scopus 로고
    • Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. preventive services task force
    • U.S. Preventive Services Task Force...: -
    • Wolff T, Witkop CT, Miller T, Syed SB, U.S. Preventive Services Task Force.2009.Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. preventive services task force.Ann Intern Med 150:632-639.
    • (2009) Ann Intern Med , vol.150 , pp. 632-639
    • Wolff, T.1    Witkop, C.T.2    Miller, T.3    Syed, S.B.4
  • 69
    • 79960484375 scopus 로고    scopus 로고
    • Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation
    • Wutz A.2011.Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation.Nat Rev Genet 12:542-553.
    • (2011) Nat Rev Genet , vol.12 , pp. 542-553
    • Wutz, A.1
  • 70
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder JA, Walsh CP, Bestor TH, et al.1997.Cytosine methylation and the ecology of intragenomic parasites.Trends Genet 13:335-340.
    • (1997) Trends Genet , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 71
    • 44749094641 scopus 로고    scopus 로고
    • Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure
    • Yu Z, Bhandari A, Mannik J, et al.2008.Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure.Dev Biol 319:56-67.
    • (2008) Dev Biol , vol.319 , pp. 56-67
    • Yu, Z.1    Bhandari, A.2    Mannik, J.3
  • 72
    • 0346752110 scopus 로고    scopus 로고
    • Millions of years of evolution preserved: a comprehensive catalog of the processed pseudogenes in the human genome
    • Zhang Z, Harrison PM, Liu Y, et al.2003.Millions of years of evolution preserved: a comprehensive catalog of the processed pseudogenes in the human genome.Genome Res 13:2541-2558.
    • (2003) Genome Res , vol.13 , pp. 2541-2558
    • Zhang, Z.1    Harrison, P.M.2    Liu, Y.3


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