The incompatibility mechanism based on the interaction of multiple-components for Flos Genkwa and Radix et Rhizoma Glycyrrhizae

Yaoxue Xuebao

Volumn 47, Issue 8, 2012, Pages 1043-1048

  Chen, Yan Yan ^a   Qian, Da Wei ^a   Shang, Er Xin ^a   Qian, Ye Fei ^a   Liu, Pei ^a   Su, Shu Lan ^a   Guo, Jian Ming ^a   Tang, Yu Ping ^a   Duan, Jin Ao ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Drug interaction; Flos Genkwa; Incompatibility; Radix et Rhizoma Glycyrrhizae; Toxicity

Indexed keywords

DITERPENE; HERBACEOUS AGENT; UNCLASSIFIED DRUG; VINEGAR; YUANHUACINE; YUANHUAJINE;

ARTICLE; DISSOLUTION; FLOS GENKWA; GLYCYRRHIZA; HERB; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN;

ACETIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DAPHNE; DITERPENES; DRUG INCOMPATIBILITY; FLOWERS; GLYCYRRHIZA URALENSIS; PLANT ROOTS; PLANTS, MEDICINAL; RHIZOME; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; TERPENES;

EID: 84867617690     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Su SL, Duan JA, Li WL, et al. Exploration the toxicity/increase virulence mechanisms of "eighteen incompatible medications" based on chemical substances [J]. Chin J Exp Tradit Med Form, 2010, 16: 123-129.
2. Wang C, Wang YG, Liang QD, et al. Analysis of chemical composition in the combination of monkshood and pinellia by UPLC/Q-TOFMS with multivariate statistical analysis [J]. Acta Pharm Sin, 2010, 45: 1301-1306.
3. Huang BB, Li GF, Ren F, et al. Effect of Glycyrrhiza inflata and Daphne genkwa on permeabilities of rhodamine 123, a P-glycoprote in substrate across rat jejunum membranes in vitro [J]. China J Chin Mater Med, 2008, 33: 2521-2526.
4. Xiao CR, Wang YG, Dai FG, et al. The effect of aconitum coadministration with lilac Daphne on cytochrome P450 in rat liver [J]. Chin J Exp Tradit Med Form, 2006, 12: 48-50.
5. Wang WQ, Luo Y. Impact of combining liquorice with kansui root, spurge, seaweed or lilac Daphne flower bud on the functions of heart, liver and kidney in rat [J]. Chin J Clin Reh, 2004, 8: 3682-3683. (Pubitemid 39030247)
6. Shi MJ, Wang WF, Li F, et al. HPLC comparative analysis of different compatibility ways of Chinese Medicine Radix Glycyrhizae and Flos Genkwa [J]. Chin Arch Tradit Chin Med, 2011, 29: 2784-2786.
7. Hu BH, Shao H, He ZW, et al. Study on the constituent of the yuanhua's flower buds - isolation and structure of yuanhuapine [J]. Acta Chim Sin, 1986, 44: 843-845.
8. Zhang SX, Li XN, Zhang FH, et al. Preparation of yuanhuacine and relative daphne diterpene esters from Daphne genkwa and structure - activity relationship of potent inhibitory activity against DNA topoisomerase I [J]. Bioorg Med Chem, 2006, 14: 3888-3895.
9. Zhang QY, Ye M. Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice) [J]. J Chromatogr A, 2009, 1216: 1954-1969.
10. Zhan ZJ, Fan CQ, Ding J, et al. Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa [J]. Bioorg Med Chem, 2005, 13: 645-655. (Pubitemid 40093606)
11. Ma HY, Li X, Li N, et al. Comparative analysis on surface activity of glycyrrhiza Radix and its active ingredients [J]. Mod Pharm Clin, 2011, 26: 227-229.
12. Ma ZC, Zhou SS, Liang QD, et al. UPLC-TOF/MS based chemical profiling approach to evaluate toxicity-attneuated chemical composition in combination of ginseng and Radix Aconiti Praeparata [J]. Acta Pharm Sin, 2011, 46: 1488-1492.
13. Su SL, Duan JA, Zhu HX, et al. Analysis of morphic traits between physical and chemical properties and chemical constituents based on different combinations of Shaofu Zhuyu decoction [J]. China J Chin Mater Med, 2011, 36: 1280-1285.