Feedforward and feedback regulation of the MAPK and PI3K oscillatory circuit in breast cancer

Cellular Signalling

Volumn 25, Issue 1, 2013, Pages 26-32

  Hu, Huizhong ^a,b,c   Goltsov, Alexey ^a,b,c   Bown, James L ^a,b,c   Sims, Andrew H ^a,b,c   Langdon, Simon P ^a,b,c   Harrison, David J ^a,b,c   Faratian, Dana ^a,b,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF ABERTAY DUNDEE   (United Kingdom)

^c UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Breast cancer; HER2; MAPK; Oscillation; PI3K; Systems biology

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; CANCER CELL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME REGULATION; FEEDBACK SYSTEM; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; ONCOGENE; OSCILLATION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MCF-7 CELLS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 84867598386     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.09.014     Document Type: Article

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