Protective effects of curcumin and vitamin E on carbon tetrachloride-induced nephrotoxicity in rats

EXCLI Journal

Volumn 11, Issue , 2012, Pages 641-650

  Venkatanarayana, G ^a   Sudhakara, G ^a   Sivajyothi, P ^a   Indira, Pala ^a  

^a SRI KRISHNADEVARAYA UNIVERSITY   (India)

Author keywords

Carbon tetrachloride; Curcumin; Silymarin; Vitamin E

Indexed keywords

ALBUMIN; ALPHA TOCOPHEROL; CREATININE; CURCUMIN; GLUTATHIONE PEROXIDASE; SILYMARIN; SUPEROXIDE DISMUTASE; UREA;

ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; ENZYME ACTIVITY; HISTOPATHOLOGY; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY MASS; MALE; NEPHROTOXICITY; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; RAT; TREATMENT DURATION; UREA BLOOD LEVEL;

EID: 84867595750     PISSN: None     EISSN: 16112156     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Adewole SO, Salako AA, Doherty OW, Naicker T. Effect of melatonin on carbon tetrachloride-induced kidney injury in wistar rats. BMC Public Health 2007;10: 153-64.
2. Beers RF, Sizer IW. A spectrophotometric method for measuring the breakdown of ydrogen peroxide by catalase. J Biol Chem 1952;195:133-40.
3. Biswas SK, McClure D, Jimenez LA, Megson IL, Rahman I. Curcumin induces glutathione biosynthesis and inhibits NFkappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxidant Redox Signaling 2005;7:32-41.
4. Cohly HHP, Taylor A, Angel MF, Salahudeen AK. Effect of turmeric, tumerin and curcumin on H2O2-induced renal epithelial (LLC-PK1) cell injury. Free Radic Biol Med 1998;24:49-54.
5. Duncan DB. Multiple range and multiple F tests. Biometrics 1955;11:1-42.
6. Ellman G. Tissue sulphhydril. Arch Biochem Biophys 1959;82:70-7.
7. Farombi EO, Ekor M. Curcumin attenuates gentamicin induced renal oxidative damage in rats. Food Chem Toxicol 2006;44:1443-8.
8. Habig WH, Pabst MJ, Jakoby WB. Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974;246:7130-9.
9. Harris HR. On the rapid conversion of haematoxylin into haematein in staining reactions. J Appl Microsc 1900;3;777-80.
10. Hughes AK, Stricklett K, Padilla E, Kohan DE. Effect of reactive oxygen species on endothelin-1 production by human mesangial cells. Kidney Int 1996;49:181-9.
11. Humason GL. Animal tissue techniques. 3rd ed. San Francisco, CA: Freeman, 1972.
12. Ivor JB, Schneider MD. Learning from failure: congestive heart failure in the post genomic age. Review series introduction. J Clin Invest 2005;115:495-9.
13. Jena S, Chainy GB. Regulation of expression of antioxidant enzymes by vitamin E and curcumin in L-thyroxine-induced oxidative stress in rat renal cortex. Mol Biol Rep 2011;38:1047-54.
14. Joe B, Vijaykumar M, Lokesh BR. Biological properties of curcumin-cellular and molecular mechanisms of action. Crit Rev Food Sci Nutr 2004;44:97-111.
15. Khan MR, Ahmed D. Protective effects of Digera muricata (L.) Mart. on testis against oxidative stress of carbon tetrachloride in rat. Food Chem Toxicol 2009;47:1393-9.
16. Khan MR, Siddique F. Antioxidant effects of Citharexylum spinosum in CCl4 induced nephrotoxicity in rat. Exp Toxicol Pathol 2012;64:349-55.
17. Khan MR, Rizvi W, Khan GN, Khan RA, Shaheen S. Carbon tetrachloride induced nephrotoxicity in rat: protective role of Digera muricata. J Ethnopharmacol 2009; 122:91-9.
18. Knight JA, Cheung AK, Pieper RK, Servilla K. Increased urinary lipoperoxide levels in renal transplant patients. Ann Clin Lab Sci 1989;19:238-41.
19. Kumar G, Banu GS, Pandian MR. Evaluation of the antioxidant activity of Trianthema portulacastrum L. Ind J Pharmacol 2005;37:331-3.
20. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin Phenol Reagent. J Biol Chem 1951; 193:265-75.
21. Marklund SL, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-74.
22. McLean EK, McLean AE, Sutton PM. Instant cirrhosis. Improved method for producing liver cirrhosis of rats by stimulus administration of carbon tetrachloride and pontobarbitone. Br J Exp Pathol 1969;50: 502-6.
23. Moawad KM. Possible prophylactic effects of vitamin E or lycopene treatment on renal toxicity induced by CCL4 administration in albino rats. World J Zool 2007;2(2):19-28.
24. Ogeturk M, Kus I, Colakoglu N, Zararsiz I, Ilhan N, Sarsilmaz M. Caffeic acid henethyl ester protects kidneys against carbon tetrachloride toxicity in rats. J Ethnopharmacol 2005;28:97:273-80.
25. Okada K, Wangpoentrakul C, Tanaka T, Toyokuni S, Uchida K, Osawa T. Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice. J Nutr 2001;131:2090-5.
26. Ozsoy N, Can A, Yanardag R, Akev N. Antioxidant activity of Smilax excelsa L. leaf extracts. Food Chem 2008;110:571-83.
27. Pinto RE, Bartley W. The effect of age and sex on glutathione reductase and glutathione peroxidase activities and on aerobic GSH oxidation in rat liver homogenates. Biochem J 1969;112:109-15.
28. Rao CV, Rivenson A, Simi B, Reddy BS. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res 1995;55:259-66.
29. Rechnagel RO, Glende EA, Dolak JA, Waller RL. Mechanisms of carbon tetrachloride toxicity. J Pharmacol Exp Ther 1989;43: 139-54.
30. Reddy AC, Lokesh BR. Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron. Mol Cell Biochem 1994;137:1-8.
31. Reiter RJ, Tan D, Osuna C, Gitto E. Actions of melatonin in the reduction of oxidative stress. J Biomed Sci 2000;7:444-58.
32. Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DC, Hoekstra WG. Selenium: biochemical roles as a component of glutathione peroxidase. Science 1973;179: 588-90.
33. Roy CK, Kamath JV, Asad M. Hepatoprotective activity of Psidium guajava Linn. leaf extract. Indian J Exp Biol 2006;44:305-11.
34. Ruby AJ, Kuttan G, Babu KD, Rajasekharan KN, Kuttan R. Antitumour and antioxidant activity of natural curcuminoids. Cancer Lett 1995;94:79-83.
35. Shahani S. Evaluation of hepatoprotective efficacy of APCL-a polyherbal formulation in vivo in rats. Indian Drugs 1998;36:628-31.
36. Soon YY, Tan BKH. Evaluation of the hypoglycemic and anti-oxidant activities of Morinda officinalis in streptozotocininduced diabetic rats. Singapore Med J 2002;43:77-85.
37. Sreejayan N, Rao MN. Free radical scavenging activity of curcuminoids. Arzneimittelforschung 1996;46:169-71.
38. Sreejayan N, Rao MN. Nitric oxide scavenging by curcuminoids. J Pharm Pharmacol 1997;49:105-7.
39. Sreepriya M, Bali G. Effects of administration of embelin and curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/phenobarbital-induced hepato carcinogenesis in Wistar rats. Mol Cell Biochem 2006;284:49-55.
40. Sundaram R, Mitra SK. Antioxidant activity of ethyl acetate soluble fraction of Acacia arabica bark in rats. Indian J Pharmacol 2007;39:33-8.
41. Tirkey N, Kaur G, Vij G, Chopra K. Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys. BMC Pharmacol 2005;5:15.
42. Unnikrishnan MK, Rao MN. Curcumin inhibits nitrogen dioxide induced oxidation of hemoglobin. Mol Cell Biochem 1995;146: 35-7.