Antioxidant activity of ethyl acetate soluble fraction of Acacia arabica bark in rats

Indian Journal of Pharmacology

Volumn 39, Issue 1, 2007, Pages 33-38

  Sundaram, R ^a   Mitra, S K ^a  

^a Himalaya Health Care   (India)

Author keywords

Antioxidant; Free radical scavenger; Hepatoprotective; Mimosaceae; Plant extract

Indexed keywords

ACACIA ARABICA EXTRACT; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ACACIA; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BARK; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DOSE INCREASE; DRUG EFFECT; DRUG EFFICACY; DRUG ISOLATION; DRUG SCREENING; ENZYME BLOOD LEVEL; FRACTIONATION; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; RAT; SOLVENT EXTRACTION; THIN LAYER CHROMATOGRAPHY;

EID: 33847725920     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: 10.4103/0253-7613.30761     Document Type: Article

References (26)

1. Maxwell SJ. Prospects for the use of antioxidant therapies. Drugs 1995;49:345-61.
2. Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95.
3. Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998;78:547-81.
4. nd ed. Clarendon Press: Oxford; 1989.
5. Halliwell B. Drug antioxidant effects. A basis for drug selection? Drugs 1991;42:569-605.
6. Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 2000;71:23-43.
7. The Wealth of India. In: Acacia nilotica. Publication and information directory. CSIR: New Delhi; 1985. p. 37-41.
8. Malan E. Derivatives of (+)-catechin-5-gallate from the bark of Acacia nilotica. Phytochem 1991;30:2737-9.
9. Lee H, Won NH, Kim KH, Lee H, Jun W, Lee KW. Antioxidant effects of aqueous extract of Terminalia chebula in vivo and in vitro. Biol Pharm Bull 2005;28:1639-44.
10. Mitra SK, Venkataranganna MV, Sundaram R, Gopumadhavan S. Effect of HD-03, a herbal formulation, an antioxidant defense system in rats. Phytother Res 1998;12:114-7.
11. 3 in vitro by tissues and tissue constituents. J Pharm Exp Ther 1961;134:311-8.
12. Venkataranganna MV, Mitra SK, Vidya TJ. Preliminary investigation on the hepatoprotective activity of Liv.52 Protec (Poultry feed supplement). Indian Vet Med J 2001;25:157-60.
13. Wang PY, Kaneko T, Tsukada H, Nakano M, Nakajima T, Sato A. Time courses of hepatic injuries induced by chloroform and by carbon tetrachloride: Comparison of biochemical and histopathological changes. Arch Toxicol 1997;71:638-45.
14. Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxaloacetate and glutamic pyruvic transaminases. Am J Clin Pathol 1957;28:56-63.
15. Ohkawa H, Ohishi N, Yogi K. Assay of lipid peroxides in animal tissue by thiobarbituric reaction. Anal Biochem 1979;95:351-8.
16. Kono Y. Generation of superoxide radical during auto oxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 1978;186:189-95.
17. Beers RF Jr, Sizer IW. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 1952;195:133-40.
18. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959;80:70-7.
19. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-69.
20. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement by folin phenol reagent. J Biol Chem 1951;193:265-72.
21. Mehendale HM. Tissue repair: An important determinant of final outcome of toxicant-induced injury. Toxicol Pathol 2005;33:41-51.
22. Reynolds ES. Comparison of early injury to liver endoplasmic reticulum by halomethanes, hexachloroethane, benzene, toluene, bromobenzene, ethionine, thioacetamide and dimethyl nitrosamine. Biochem Pharmacol 1972;21:2255-61.
23. Kähkönen MP, Hopia AI, Vuorela HJ, Rauha J, Pihlaja K, Kujala TS, et al. Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem 1999;47:3954-62.
24. Soobrattee MA, Neergheen VS, Luximon-Ramma A, Aruoma OI, Bahorun T. Phenolics as potential antioxidant therapeutic agents: Mechanism and actions. Mutat Res 2005;579:200-13.
25. Rice-Evans CA, Miller NJ, Paganga G. Antioxidant properties of phenolic compounds. Trends Plant Sci 1997;2:152-9.
26. Mikstacka R, Gnojkowski J, Baer-Dubowska W. Effect of natural phenols on the catalytic activity of cytochrome P450 2E1. Acta Biochim Pol 2002;49:917-25.