New Surfactant with SP-B and C Analogs Gives Survival Benefit after Inactivation in Preterm Lambs

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Seehase, Matthias ^a,e   Collins, Jennifer J P ^a   Kuypers, Elke ^a   Jellema, Reint K ^a   Ophelders, Daan R M G ^a   Ospina, Olga L ^c,d   Perez Gil, J ^c   Bianco, Federico ^b   Garzia, Raffaella ^b   Razzetti, Roberta ^b   Kramer, Boris W ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CHIESI FARMACEUTICI S P A   (Italy)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^e UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 PALMITOYL 2 OLEOYL SN GLYCERO 3 PHOSPHOGLYCEROL; ALBUMIN; BIOLOGICAL MARKER; CHF 5633; CYSTEINYLTRYPTOPHYLLEUCYLCYSTEINYLARGINYLALANYLLEUCYLISOLEUCYLLYSYLARGINYLISOLEUCYLGLUTAMINYLALANYLLEUCYLISOLEUCYLPROPYLLYSYLGLYCYLGLYCYLARGINYLLEUCYLLEUCYLPROPYLGLUTAMINYLLEUCYLVALYLCYSTEINYLARGINYLLEUCYLVALYLLEUCYLVALYLLEUCYLARGINYLCYSTEINYLSERINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; ISOLEUCYLPROPYLSERYLSERYLPROPYLVALYLHISTIDINYLLEUCYLLYSYLARGINYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLISOLEUCYLLEUCYLLEUCYLLEUCYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCYLLEUCYLLEUCYLGLYCYLLEUCINE; LUNG SURFACTANT; PHOSPHOLIPID; PORACTANT; SODIUM; SURFACTANT PROTEIN B DERIVATIVE; SURFACTANT PROTEIN C DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PH; ARTICLE; ARTIFICIAL VENTILATION; AUTOPSY; CONTROLLED STUDY; DISEASE MARKER; DRUG INACTIVATION; FEMALE; FETUS; GESTATIONAL AGE; HISTOPATHOLOGY; IN VIVO STUDY; LUNG LAVAGE; MALE; NONHUMAN; OXYGEN TENSION; OXYGENATION; PNEUMONIA; PREMATURITY; RESPIRATORY DISTRESS SYNDROME; SURFACE TENSION; SURVIVAL RATE;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ANIMALS; BIOLOGICAL AGENTS; FEMALE; LUNG; MALE; PHOSPHATIDYLGLYCEROLS; PHOSPHOLIPIDS; PREGNANCY; PREMATURE BIRTH; PULMONARY SURFACTANT-ASSOCIATED PROTEIN B; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; PULMONARY SURFACTANTS; SHEEP;

EID: 84867584677     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047631     Document Type: Article

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