A synthetic surfactant based on a poly-Leu SP-C analog and phospholipids: Effects on tidal volumes and lung gas volumes in ventilated immature newborn rabbits

Journal of Applied Physiology

Volumn 95, Issue 5, 2003, Pages 2055-2063

  Johansson, Jan ^a,c   Some, Margareta ^b   Linderholm, Britt Marie ^b   Almlén, Andreas ^a,b   Curstedt, Tore ^b   Robertson, Bengt ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Leucine; Membrane peptide; Peptide synthesis; Respiratory distress syndrome; Secondary structure; Surfactant protein C

Indexed keywords

1 PALMITOYL 2 OLEOYL 3 GLYCEROPHOSPHORYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; GLYCEROPHOSPHORYLCHOLINE DERIVATIVE; LEUCINE; LUNG SURFACTANT EXTRACT; MEMBRANE PROTEIN; PHOSPHOLIPID; POLYAMINOACID; POLYLEUCINE; POLYLEUCINE SURFACTANT PROTEIN C DERIVATIVE; SP C33; SURFACTANT; SURFACTANT PROTEIN C; SYNTHETIC SURFACTANT; UNCLASSIFIED DRUG;

AERATION; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; HISTOPATHOLOGY; LIPID COMPOSITION; LUNG GAS VOLUME; LUNG VOLUME; NEWBORN; NEWBORN PERIOD; NONHUMAN; PEPTIDE SYNTHESIS; POSITIVE END EXPIRATORY PRESSURE; PREMATURITY; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RABBIT; RESPIRATORY DISTRESS SYNDROME; RESPIRATORY EPITHELIUM; SURFACE PROPERTY; TIDAL VOLUME;

EID: 0142217949     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00153.2003     Document Type: Article

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