Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits

Neonatology

Volumn 98, Issue 1, 2010, Pages 91-99

  Almlén, Andreas ^a   Walther, Frans J ^b,c   Waring, Alan J ^b,d   Robertson, Bengt ^a   Johansson, Jan ^e   Curstedt, Tore ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Pulmonary surfactant; Respiratory distress syndrome; Surfactant protein B; Surfactant protein C; Synthetic peptide; Synthetic surfactant

Indexed keywords

1 PALMITOYL 2 OLEOYLGLYCERO 3 PHOSPHOGLYCEROL; CYSTEINYLTRYPTOPHYLLEUCYLCYSTEINYLARGINYKALANYLLEUCYLISOLEUCYLLYSYLARGINYLISOLEUCYLGLUTAMINYLALANYLMETHIONYLISOLEUCYLPROLYLLYSYLGLYCYLGLYCYLARGINYLMETHIONYLLEUCYLPROLYLGLUTAMINYLLEUCYLVALYLCYSTEINYLARGINYLLEUCYLVALYLLEUCYLARGINYLCYSTEINYLSERINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; GLYCEROL DERIVATIVE; ISOLEUCYLPROLYLSERYLSERYLPROLYLVALYLHISTIDYLLEUCYLLYSYLARGINYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLISOLEUCYLLEUCYLLEUCYLLEUCYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCYLLEUCINE; ISOLEUCYLPROLYLSERYLSERYLPROLYLVALYLHISTIDYLLEUCYLLYSYLARGINYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLISOLEUCYLLEUCYLLEUCYLLEUCYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCYLLEUCYLMETHIONYLGLYCYLLEUCINE; LEUCYLLEUCYLLEUCYLLYSYLLEUCYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLYSYLLEUCYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLYSYLLEUCYLLEUCYLLEUCINE; LEUCYLLEUCYLLYSYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLYSYLLEUCYLLYSYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLYSYLLEUCYLLYSYLLEUCYLLEUCINE; OXYGEN; PORACTANT; PROTEIN DERIVATIVE; SURFACTANT; SURFACTANT PROTEIN B; SURFACTANT PROTEIN C; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL DEATH; CONTROLLED STUDY; DRUG EFFECT; DRUG MIXTURE; HISTOPATHOLOGY; LUNG ALVEOLUS CELL; LUNG VOLUME; NEWBORN; NONHUMAN; OXYGEN THERAPY; PREMATURITY; PRIORITY JOURNAL; RABBIT; RESPIRATORY DISTRESS SYNDROME; STRUCTURE ACTIVITY RELATION; TIDAL VOLUME; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; FEMALE; HUMAN; RESPIRATORY DISTRESS SYNDROME, NEWBORN;

ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; PEPTIDES; PREMATURE BIRTH; PULMONARY SURFACTANT-ASSOCIATED PROTEIN B; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; RABBITS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, NEWBORN; SURFACE-ACTIVE AGENTS; TIDAL VOLUME;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SUS;

EID: 75149140539     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000276980     Document Type: Article

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