Surfactant protein A recruits neutrophils into the lungs of ventilated preterm lambs

American Journal of Respiratory and Critical Care Medicine

Volumn 163, Issue 1, 2001, Pages 158-165

  Kramer, Boris W ^a   Jobe, Alan H ^a   Bachurski, Cindy J ^a   Ikegami, Machiko ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CELL ADHESION MOLECULE; CYTOKINE; HERMES ANTIGEN; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; RECOMBINANT PROTEIN; SURFACTANT PROTEIN A; SURFACTANT PROTEIN C; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; GESTATIONAL AGE; INFLAMMATION; LUNG ALVEOLUS SURFACE TENSION; LUNG FUNCTION; LUNG LAVAGE; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEUTROPHIL CHEMOTAXIS; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PREMATURITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

EID: 0035152927     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.163.1.2005084     Document Type: Article

References (38)

1. Oxygen radicals, cytokines, adhesion molecules and lung injury in neonates
2. Immunomodulatory functions of surfactant
3. Surfactant metabolism in surfactant protein A-deficient mice
4. Tolerance of SP-A deficient mice to hyperoxia or exercise
5. Altered surfactant function and structure in SP-A gene targeted mice
6. Surfactant protein A-deficient mice are susceptible to group B streptococcal infection
7. Surfactant protein-A (SP-A) binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A deficient mice
8. Surfactant protein A downregulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes
9. Surfactant protein A enhances the binding and deacylation of E. coli LPS by alveolar macrophages
10. Effects of endotoxin on surfactant protein A and D stimulation of NO production by alveolar macrophages
11. Pulmonary surfactant protein A modulates the cellular response to smooth and rough lipopolysaccharides by interaction with CD14
12. Nitric oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein A
13. Surfactant protein A stimulation of inflammatory cytokine and immunoglobulin production
14. Surfactant protein A protects growing cells and reduces TNF-alpha activity from LPS stimulated macrophages
15. Lung injury and surfactant metabolism after hyperventilation of premature lambs
16. Effects of different styles of ventilation on cytokine expression in the preterm lamb lung
17. Amniotic fluid cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1β, and interleukin-8) and the risk for the development of bronchopulmonary dysplasia
18. Surfactant protein-A, phosphatidylcholine, and surfactant inhibitors in epithelial lining fluid - Correlation with surface activity, severity of respiratory distress syndrome, and outcome in small premature infants
19. Surfactant proteins A and D in premature baboons with chronic lung injury: Evidence for an inhibition of secretion
20. Neonatal immunity: How well has it grown up?
21. Effects of a surfactant-associated protein and calcium ions on the structure and surface activity of lung surfactant lipids
22. Lung function in premature lambs and rabbits treated with a recombinant SP-C surfactant
23. Dosing and delivery of a recombinant surfactant in lung-injury adult sheep
24. Treatment of ARDS with rSP-C surfactant
25. Positive end expiratory pressure preserves surfactant function in preterm lambs
26. Tidal volume effects on surfactant treatment responses with the initiation of ventilation in preterm lambs
27. Antenatal endotoxin and glucocorticoid effects on the lungs of preterm lambs
28. Amnion chorion and lung tissue cytokine response to intra amniotic endotoxin in fetal sheep
29. Neutrophil CD11b expression as a diagnostic marker for early onset neonatal infection
30. Surfactant protein A regulates cytokine production in the monocytic cell line THP-1
31. Surfactant associated protein-A inhibits human lymphocyte proliferation and IL-2 production
32. Injurious ventilatory strategies increase cytokines and c-fos m RNA expression in an isolated rat lung mode
33. Neutrophil function in newborn infants
34. Decreased adherence, chemotaxis and phagocytic activities of neutrophils from preterm neonates
35. Binding of pulmonary proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages
36. Pulmonary surfactant protein-A stimulates chemotaxis of alveolar macrophage
37. Decreased surfactant protein-A in patients with bacterial pneumonia
38. Inflammatory bronchopulmonary response of preterm infants with microbial colonisation of the airways at birth